Zobrazeno 1 - 10
of 413
pro vyhledávání: '"Luigi Aloe"'
Autor:
George N. Chaldakov, Luigi Aloe, Stanislav G. Yanev, Marco Fiore, Anton B. Tonchev, Manlio Vinciguerra, Nikolai T. Evtimov, Peter Ghenev, Krikor Dikranian
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 961 (2024)
Many routes may lead to the transition from a healthy to a diseased phenotype. However, there are not so many routes to travel in the opposite direction; that is, therapy for different diseases. The following pressing question thus remains: what are
Externí odkaz:
https://doaj.org/article/e528d37e1f31482dafc8ff3f416bb83d
Autor:
Vito Antonio Baldassarro, Maura Cescatti, Maria Luisa Rocco, Luigi Aloe, Luca Lorenzini, Luciana Giardino, Laura Calzà
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionNerve growth factor (NGF) is a pleiotropic molecule acting on different cell types in physiological and pathological conditions. However, the effect of NGF on the survival, differentiation and maturation of oligodendrocyte precursor cells
Externí odkaz:
https://doaj.org/article/71a10ef3f8424586b7c8629e8f6b1636
Autor:
Marzia Moretti, Riccardo Caraffi, Luca Lorenzini, Ilaria Ottonelli, Michele Sannia, Giuseppe Alastra, Vito Antonio Baldassarro, Alessandro Giuliani, Jason Thomas Duskey, Maura Cescatti, Barbara Ruozi, Luigi Aloe, Maria Angela Vandelli, Luciana Giardino, Giovanni Tosi, Laura Calzà
Publikováno v:
Cells, Vol 12, Iss 9, p 1331 (2023)
Spinal cord injury (SCI) is characterized by a cascade of events that lead to sensory and motor disabilities. To date, this condition is irreversible, and no cure exists. To improve myelin repair and limit secondary degeneration, we developed a multi
Externí odkaz:
https://doaj.org/article/59aa99aac00f4692af8891a3ebe9739f
Publikováno v:
International Journal of Ophthalmology, Vol 14, Iss 2, Pp 209-216 (2021)
AIM: To develop an experimental model of endogenous nerve growth factor (NGF) deprivation by retrobulbar administration of purified neutralizing anti-NGF antibodies in young Sprague-Dawley rats and provide further information on NGF expression in the
Externí odkaz:
https://doaj.org/article/62dbf955e2ff4cf08268decd214084d7
Autor:
Giuseppe Alastra, Luigi Aloe, Vito Antonio Baldassarro, Laura Calzà, Maura Cescatti, Jason Thomas Duskey, Maria Letizia Focarete, Daria Giacomini, Luciana Giardino, Valentina Giraldi, Luca Lorenzini, Marzia Moretti, Irene Parmeggiani, Michele Sannia, Giovanni Tosi
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Nerve growth factor (NGF) was the first-discovered member of the neurotrophin family, a class of bioactive molecules which exerts powerful biological effects on the CNS and other peripheral tissues, not only during development, but also during adulth
Externí odkaz:
https://doaj.org/article/ec0d8d2337764f8db0f1c1dc814f5398
Autor:
Luigi Aloe, Maria Luisa Rocco
Publikováno v:
Annali dell'Istituto Superiore di Sanità, Vol 51, Iss 1, Pp 5-10 (2015)
It has been shown that topical nerve growth factor (NGF) administration induces healing action on human cutaneous, corneal and pressure ulcers, glaucoma, maculopathy and retinitis pigmentosa suggesting a therapeutic potential of NGF in human ophthalm
Externí odkaz:
https://doaj.org/article/36abb2d9332240c29872d20c92f74dc7
Autor:
Luigi Aloe, George N. Chaldakov
Publikováno v:
Balkan Medical Journal, Vol 30, Iss 1, Pp 4-7 (2013)
At the end of the 19th century, it was envisaged by Santiago Ramon y Cajal, but not, proven, that life at the neuronal level requires trophic support. The proof was obtained in the early 1950's by work initiated by Rita Levi-Montalcini (RLM) discover
Externí odkaz:
https://doaj.org/article/1607dabca36141af84dd5ae2c60ec7a7
Autor:
George N. Chaldakov, Neşe Tunçel, Jerzy Beltowski, Marco Fiore, Gorana Ranćić, Anton Tonchev, Plamen Panayotov, Nikolai Evtimov, Alexander Hinev, Deyan Anakievski, Peter Ghenev, Luigi Aloe
Publikováno v:
Balkan Medical Journal, Vol 29, Iss 1, Pp 2-9 (2012)
White adipose tissue (WAT) is a dynamic multicellular assembly composed of adipocytes and stromovascular cells, including fibroblasts, endothelial and immune cells, nerve fibers, and stem cells. In humans, WAT is a responsive and secretory (endocrine
Externí odkaz:
https://doaj.org/article/4dbcea98b4a84827af6a137ded84a883
Publikováno v:
Annali dell'Istituto Superiore di Sanità, Vol 47, Iss 3, Pp 284-289 (2011)
The aim of this study was to investigate the effect of nerve growth factor (NGF) administration on retinal ganglion cells (RGCs) in experimentally induced glaucoma (GL) and diabetic retinopathy (DR). GL was induced in adult rats by injection of hyper
Externí odkaz:
https://doaj.org/article/053982bed6064ab9b13bf59b4fefad51
Publikováno v:
Annali dell'Istituto Superiore di Sanità, Vol 45, Iss 4, Pp 439-442 (2009)
Age-related macular degeneration (ARMD) is a severe disease affecting visual function in the elderly. Currently available surgical and medical options do not guarantee a significant impact on the outcome of the disease. We describe the effects of ner
Externí odkaz:
https://doaj.org/article/4ed97f1073ad45db9aaba7389e5f505a