Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Luigi, Martino"'
Autor:
Sebastian Kupka, Diego De Miguel, Peter Draber, Luigi Martino, Silvia Surinova, Katrin Rittinger, Henning Walczak
Publikováno v:
Cell Reports, Vol 16, Iss 9, Pp 2271-2280 (2016)
Recruitment of the deubiquitinase CYLD to signaling complexes is mediated by its interaction with HOIP, the catalytically active component of the linear ubiquitin chain assembly complex (LUBAC). Here, we identify SPATA2 as a constitutive direct bindi
Externí odkaz:
https://doaj.org/article/11f4219692dd413a9e712d8ef47b70b6
Autor:
Peter Draber, Sebastian Kupka, Matthias Reichert, Helena Draberova, Elodie Lafont, Diego de Miguel, Lisanne Spilgies, Silvia Surinova, Lucia Taraborrelli, Torsten Hartwig, Eva Rieser, Luigi Martino, Katrin Rittinger, Henning Walczak
Publikováno v:
Cell Reports, Vol 13, Iss 10, Pp 2258-2272 (2015)
Ubiquitination and deubiquitination are crucial for assembly and disassembly of signaling complexes. LUBAC-generated linear (M1) ubiquitin is important for signaling via various immune receptors. We show here that the deubiquitinases CYLD and A20, bu
Externí odkaz:
https://doaj.org/article/6c17437bc05345f6a259e00153b83b21
Autor:
Marzio Di Feo, Luigi Martino
Publikováno v:
Governing Complexity in Times of Turbulence ISBN: 9781800889651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90fb91fdb0aa1db7aa91cac2763f94a6
https://doi.org/10.4337/9781800889651.00014
https://doi.org/10.4337/9781800889651.00014
Autor:
Luigi Martino, Louise Holland, Evangelos Christodoulou, Simone Kunzelmann, Diego Esposito, Katrin Rittinger
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164662 (2016)
NOD-like receptors represent an important class of germline-encoded pattern recognition receptors that play key roles in the regulation of inflammatory signalling pathways. They function as danger sensors and initiate inflammatory responses and the p
Externí odkaz:
https://doaj.org/article/39dc3b049721453aaab3493311c0252e
The chapter examines the situation of critical infrastructures in Italy in the first 20 years of the new Millennium. Following the pattern of the Routledge companion, the authors identify the conditions that have characterised the government's approa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::5525bfc4b767d69c7353ad39a378ea52
http://hdl.handle.net/11585/800407
http://hdl.handle.net/11585/800407
Autor:
Sandra Kümper, H. Christian Eberl, Katrin Rittinger, Chun-wa Chung, Daniel Thomas, Henrik Johansson, David House, Yi-Chun Isabella Tsai, Luigi Martino, Marcel Muelbaier, Ken G. M. Fantom
Publikováno v:
Journal of the American Chemical Society
Modification of proteins with polyubiquitin chains is a key regulatory mechanism to control cellular behavior and alterations in the ubiquitin system are linked to many diseases. Linear (M1-linked) polyubiquitin chains play pivotal roles in several c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbdf43ab52fb7e1eafe602e5244457c4
https://doi.org/10.1021/jacs.8b13193
https://doi.org/10.1021/jacs.8b13193
Autor:
Luigi Martino, Federica Merenda
Publikováno v:
Technology and International Relations ISBN: 9781788976077
Particularly in the most recent decades, Artificial Intelligence (AI) is revolutionizing our societies in a wide range of different fields: AI devices are currently employed to assist judges, physicians, and soldiers, among others, with complex intel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2869b38878ef3c9e0b517dcad45bd3c5
https://doi.org/10.4337/9781788976077.00012
https://doi.org/10.4337/9781788976077.00012
Autor:
Luigi Martino
This book presents a detailed and innovative analysis of the governance, policies and ecosystem that define the Italian cybersecurity posture. It explores the complex interplay between technology and policy in shaping national security strategies in