Zobrazeno 1 - 10
of 865
pro vyhledávání: '"Luigi, Mariani"'
Autor:
Tomás A. Martins, Deniz Kaymak, Nazanin Tatari, Fiona Gerster, Sabrina Hogan, Marie-Françoise Ritz, Valerio Sabatino, Ronja Wieboldt, Ewelina M. Bartoszek, Marta McDaid, Alexandra Gerber, Alicia Buck, Aisha Beshirova, Anja Heider, Tala Shekarian, Hayget Mohamed, Manina M. Etter, Philip Schmassmann, Ines Abel, Jean-Louis Boulay, Yasuyuki Saito, Luigi Mariani, Raphael Guzman, Berend Snijder, Tobias Weiss, Heinz Läubli, Gregor Hutter
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract A significant challenge for chimeric antigen receptor (CAR) T cell therapy against glioblastoma (GBM) is its immunosuppressive microenvironment, which is densely populated by protumoral glioma-associated microglia and macrophages (GAMs). Mye
Externí odkaz:
https://doaj.org/article/54d8c2ce535347fc8b97105d49f0cbda
Autor:
Jürgen Hench, Claus Hultschig, Jon Brugger, Luigi Mariani, Raphael Guzman, Jehuda Soleman, Severina Leu, Miles Benton, Irenäus Maria Stec, Ivana Bratic Hench, Per Hoffmann, Patrick Harter, Katharina J Weber, Anne Albers, Christian Thomas, Martin Hasselblatt, Ulrich Schüller, Lisa Restelli, David Capper, Ekkehard Hewer, Joachim Diebold, Danijela Kolenc, Ulf C. Schneider, Elisabeth Rushing, Rosa della Monica, Lorenzo Chiariotti, Martin Sill, Daniel Schrimpf, Andreas von Deimling, Felix Sahm, Christian Kölsche, Markus Tolnay, Stephan Frank
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract DNA methylation analysis based on supervised machine learning algorithms with static reference data, allowing diagnostic tumour typing with unprecedented precision, has quickly become a new standard of care. Whereas genome-wide diagnostic me
Externí odkaz:
https://doaj.org/article/0728b5481b5942bf8a38046de711832e
Autor:
Sara Pusceddu, Francesca Corti, Natalie Prinzi, Federico Nichetti, Silva Ljevar, Adele Busico, Tommaso Cascella, Rita Leporati, Simone Oldani, Chiara Carlotta Pircher, Jorgelina Coppa, Veronica Resi, Massimo Milione, Marco Maccauro, Rosalba Miceli, Elena Tamborini, Federica Perrone, Carlo Spreafico, Monica Niger, Federica Morano, Filippo Pietrantonio, Ettore Seregni, Luigi Mariani, Vincenzo Mazzaferro, Giorgia Di Liberti, Giovanni Fucà, Filippo de Braud, Claudio Vernieri
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-5 (2023)
Abstract In retrospective studies, metformin use has been associated with better clinical outcomes in diabetic patients with advanced, well-differentiated neuroendocrine tumors (WDNETs). However, prospective evidence of metformin safety and activity
Externí odkaz:
https://doaj.org/article/1fcb7b069e624b61b3c438f1291779ca
Autor:
Markus Huber, Markus M. Luedi, Gerrit A. Schubert, Christian Musahl, Angelo Tortora, Janine Frey, Jürgen Beck, Luigi Mariani, Emanuel Christ, Lukas Andereggen
Publikováno v:
Frontiers in Surgery, Vol 11 (2024)
BackgroundIn clinical practice, the size of adenomas is crucial for guiding prolactinoma patients towards the most suitable initial treatment. Consequently, establishing guidelines for serum prolactin level thresholds to assess prolactinoma size is e
Externí odkaz:
https://doaj.org/article/3648aa1c9c0f40789fe478969d85717b
Autor:
Stefano Cavalieri, Eleonora Bruno, Mara Serena Serafini, Deborah Lenoci, Silvana Canevari, Laura Lopez-Perez, Liss Hernandez, Luigi Mariani, Rosalba Miceli, Cecilia Gavazzi, Patrizia Pasanisi, Elena Rosso, Francesca Cordero, Paolo Bossi, Wojciech Golusinski, Andreas Dietz, Primož Strojan, Thorsten Fuereder, Loris De Cecco, Lisa Licitra
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundThere is a strong need for preventive approaches to reduce the incidence of recurrence, second cancers, and late toxicities in head and neck squamous cell carcinoma (HNSCC) survivors. We conducted a randomized controlled trial (RCT) to asse
Externí odkaz:
https://doaj.org/article/6ddb8c97126d47debcf457fefba9d6d1
Autor:
Emma Zattarin, Luigi Mariani, Alice Menichetti, Rita Leporati, Leonardo Provenzano, Francesca Ligorio, Giovanni Fucà, Riccardo Lobefaro, Luca Lalli, Andrea Vingiani, Federico Nichetti, Gaia Griguolo, Marianna Sirico, Ottavia Bernocchi, Antonio Marra, Chiara Corti, Paola Zagami, Elisa Agostinetto, Flavia Jacobs, Pierluigi Di Mauro, Daniele Presti, Caterina Sposetti, Carlo Alberto Giorgi, Valentina Guarneri, Rebecca Pedersini, Agnese Losurdo, Daniele Generali, Giuseppe Curigliano, Giancarlo Pruneri, Filippo de Braud, Maria Vittoria Dieci, Claudio Vernieri
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 15 (2023)
Background: Cyclin-Dependent Kinase 4/6 inhibitors (CDK4/6i) combined with Endocrine Therapy (ET) are the standard treatment for patients with Hormone Receptor-positive/HER2-negative advanced breast cancer (HR+/HER2− aBC). Objectives: While CDK4/6i
Externí odkaz:
https://doaj.org/article/997ec44c91b244349cd2462f6a583683
Autor:
Emma Zattarin, Daniele Presti, Luigi Mariani, Caterina Sposetti, Rita Leporati, Alice Menichetti, Chiara Corti, Chiara Benvenuti, Giovanni Fucà, Riccardo Lobefaro, Francesca Ligorio, Leonardo Provenzano, Andrea Vingiani, Marta Del Vecchio, Gaia Griguolo, Marianna Sirico, Ottavia Bernocchi, Antonio Marra, Paola Zagami, Elisa Agostinetto, Flavia Jacobs, Pierluigi Di Mauro, Andrea Esposito, Carlo Alberto Giorgi, Luca Lalli, Laura Boldrini, Pier Paolo Berton Giacchetti, Ambra Carnevale Schianca, Valentina Guarneri, Rebecca Pedersini, Agnese Losurdo, Alberto Zambelli, Daniele Generali, Carmen Criscitiello, Giuseppe Curigliano, Giancarlo Pruneri, Filippo de Braud, Maria Vittoria Dieci, Claudio Vernieri
Publikováno v:
npj Breast Cancer, Vol 9, Iss 1, Pp 1-5 (2023)
Abstract Whether Human Epidermal growth factor Receptor 2 (HER2)-low status has prognostic significance in HR + /HER2- advanced Breast Cancer (aBC) patients treated with first-line Endocrine Therapy plus CDK 4/6 inhibitors remains unclear. In 428 pat
Externí odkaz:
https://doaj.org/article/1b8f8d9603654e7590deb24e3d8b863d
Autor:
Matthias von Rotz, Richard Kuehl, Ana Durovic, Sandra Zingg, Anett Apitz, Fanny Wegner, Helena M. B. Seth-Smith, Tim Roloff, Karoline Leuzinger, Hans H. Hirsch, Sabine Kuster, Manuel Battegay, Luigi Mariani, Stefan Schaeren, Stefano Bassetti, Florian Banderet-Uglioni, Adrian Egli, Sarah Tschudin-Sutter
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 12, Iss 1, Pp 1-10 (2023)
Abstract Background We sought to decipher transmission pathways in healthcare-associated infections with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) within our hospital by epidemiological work-up and complementary whole genome sequen
Externí odkaz:
https://doaj.org/article/d737146bcd2049c29729ee311e7df612
Autor:
Amir El Rahal, Jürgen Beck, Peter Ahlborn, Corrado Bernasconi, Serge Marbacher, Stefan Wanderer, Jan-Karl Burkhardt, Roy Thomas Daniel, Andrea Ferrari, Oliver Hausmann, Maria Kamenova, Karl Kothbauer, Katharina Lutz, Luigi Mariani, Alex Alfieri, Daniel Schöni, Philippe Schucht, Andreas Raabe, Luca Regli, Dominique Kuhlen, Martin Seule, Jehuda Soleman, Daniele Starnoni, Julien Zaldivar, Christian Zweifel, Karl Schaller, Christian Fung
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
BackgroundChronic subdural hematoma (cSDH) is a disease affecting mainly elderly individuals. The reported incidence ranges from 2.0/100,000 to 58 per 100,000 person-years when only considering patients who are over 70 years old, with an overall inci
Externí odkaz:
https://doaj.org/article/604b28e7b3424bd8a9ab6e32f2880b75