Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Luigi, Bouchard"'
Autor:
Marie-France Hivert, Luigi Bouchard, Noel T Mueller, Myriam Doyon, Patrice Perron, Curtis Tilves, Bruno Bohn, Yingan Chen, Renée Guérin, Éric Massé
Publikováno v:
BMJ Open Gastroenterology, Vol 11, Iss 1 (2024)
Objective Gut microbes and microbe-dependent metabolites (eg, tryptophan-kynurenine-serotonin pathway metabolites) have been linked to systemic inflammation, but the microbiota-metabolite-inflammation axis remains uncharacterised in children. Here we
Externí odkaz:
https://doaj.org/article/f2c9131c412c4e64bb9dc849d5633a5e
Autor:
Maria Carolina Borges, Gemma L. Clayton, Rachel M. Freathy, Janine F. Felix, Alba Fernández-Sanlés, Ana Gonçalves Soares, Fanny Kilpi, Qian Yang, Rosemary R. C. McEachan, Rebecca C. Richmond, Xueping Liu, Line Skotte, Amaia Irizar, Andrew T. Hattersley, Barbara Bodinier, Denise M. Scholtens, Ellen A. Nohr, Tom A. Bond, M. Geoffrey Hayes, Jane West, Jessica Tyrrell, John Wright, Luigi Bouchard, Mario Murcia, Mariona Bustamante, Marc Chadeau-Hyam, Marjo-Riitta Jarvelin, Martine Vrijheid, Patrice Perron, Per Magnus, Romy Gaillard, Vincent W. V. Jaddoe, William L. Lowe, Bjarke Feenstra, Marie-France Hivert, Thorkild I. A. Sørensen, Siri E. Håberg, Sylvain Serbert, Maria Magnus, Deborah A. Lawlor
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Higher maternal pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and perinatal outcomes. However, whether these associations are causal remains unclear. Methods We explored the relation of maternal pre-/ear
Externí odkaz:
https://doaj.org/article/0a4789dc4d5f4384bda3a38300dc1bb0
Autor:
Latha Kadalayil, Md. Zahangir Alam, Cory Haley White, Akram Ghantous, Esther Walton, Olena Gruzieva, Simon Kebede Merid, Ashish Kumar, Ritu P. Roy, Olivia Solomon, Karen Huen, Brenda Eskenazi, Peter Rzehak, Veit Grote, Jean-Paul Langhendries, Elvira Verduci, Natalia Ferre, Darek Gruszfeld, Lu Gao, Weihua Guan, Xuehuo Zeng, Enrique F. Schisterman, John F. Dou, Kelly M. Bakulski, Jason I. Feinberg, Munawar Hussain Soomro, Giancarlo Pesce, Nour Baiz, Elena Isaevska, Michelle Plusquin, Marina Vafeiadi, Theano Roumeliotaki, Sabine A. S. Langie, Arnout Standaert, Catherine Allard, Patrice Perron, Luigi Bouchard, Evelien R. van Meel, Janine F. Felix, Vincent W. V. Jaddoe, Paul D. Yousefi, Cecilia H. Ramlau-Hansen, Caroline L. Relton, Elmar W. Tobi, Anne P. Starling, Ivana V. Yang, Maria Llambrich, Gillian Santorelli, Johanna Lepeule, Lucas A. Salas, Mariona Bustamante, Susan L. Ewart, Hongmei Zhang, Wilfried Karmaus, Stefan Röder, Ana Claudia Zenclussen, Jianping Jin, Wenche Nystad, Christian M. Page, Maria Magnus, Dereje D. Jima, Cathrine Hoyo, Rachel L. Maguire, Tuomas Kvist, Darina Czamara, Katri Räikkönen, Tong Gong, Vilhelmina Ullemar, Sheryl L. Rifas-Shiman, Emily Oken, Catarina Almqvist, Robert Karlsson, Jari Lahti, Susan K. Murphy, Siri E. Håberg, Stephanie London, Gunda Herberth, Hasan Arshad, Jordi Sunyer, Regina Grazuleviciene, Dana Dabelea, Régine P. M. Steegers-Theunissen, Ellen A. Nohr, Thorkild I. A. Sørensen, Liesbeth Duijts, Marie-France Hivert, Vera Nelen, Maja Popovic, Manolis Kogevinas, Tim S. Nawrot, Zdenko Herceg, Isabella Annesi-Maesano, M. Daniele Fallin, Edwina Yeung, Carrie V. Breton, Berthold Koletzko, Nina Holland, Joseph L. Wiemels, Erik Melén, Gemma C. Sharp, Matt J. Silver, Faisal I. Rezwan, John W. Holloway
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-23 (2023)
Abstract Background Seasonal variations in environmental exposures at birth or during gestation are associated with numerous adult traits and health outcomes later in life. Whether DNA methylation (DNAm) plays a role in the molecular mechanisms under
Externí odkaz:
https://doaj.org/article/d655547609c94f51b01a2521002c970a
Autor:
Cécilia Légaré, Véronique Desgagné, Kathrine Thibeault, Frédérique White, Andrée-Anne Clément, Cédrik Poirier, Zhong-Cheng Luo, Michelle S. Scott, Pierre-Étienne Jacques, Patrice Perron, Renée Guérin, Marie-France Hivert, Luigi Bouchard
Publikováno v:
Biomedicines, Vol 12, Iss 6, p 1285 (2024)
Maternal blood glucose regulation adaptation to pregnancy aims to support fetal growth but may also lead to the development of gestational diabetes mellitus, the most common pregnancy complication. MiRNAs are small RNA molecules secreted and stable i
Externí odkaz:
https://doaj.org/article/bae7fa08ebb749ce8117b867cffec14a
Autor:
Amélie Taschereau, Kathrine Thibeault, Catherine Allard, Diana Juvinao-Quintero, Patrice Perron, Sharon M. Lutz, Luigi Bouchard, Marie-France Hivert
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-11 (2023)
Abstract Background In utero exposure to maternal hyperglycemia has been associated with an increased risk for the development of chronic diseases in later life. These predispositions may be programmed by fetal DNA methylation (DNAm) changes that per
Externí odkaz:
https://doaj.org/article/5df9f8d6d96c4fcaa68d8dd26b3c6c69
Autor:
Andrée-Anne Clément, Daphnée Lamarche, Marie-Hélène Masse, Cécilia Légaré, Lee-Hwa Tai, Laurence Fleury Deland, Marie-Claude Battista, Luigi Bouchard, Frédérick D’Aragon
Publikováno v:
Epigenetics, Vol 17, Iss 11, Pp 1546-1561 (2022)
Neurologically deceased organ donors (NDDs) generally display an immune response involving an intense production of pro-inflammatory cytokines referred to as the cytokine storm. The sudden surge of inflammatory mediators in circulation promotes tissu
Externí odkaz:
https://doaj.org/article/48b612bb75bf41168c5992ee951c0137
Autor:
Nora Fernandez-Jimenez, Ruby Fore, Ariadna Cilleros-Portet, Johanna Lepeule, Patrice Perron, Tuomas Kvist, Fu-Ying Tian, Corina Lesseur, Alexandra M. Binder, Manuel Lozano, Jordi Martorell-Marugán, Yuk J. Loke, Kelly M. Bakulski, Yihui Zhu, Anne Forhan, Sara Sammallahti, Todd M. Everson, Jia Chen, Karin B. Michels, Thalia Belmonte, Pedro Carmona-Sáez, Jane Halliday, M. Daniele Fallin, Janine M. LaSalle, Jorg Tost, Darina Czamara, Mariana F. Fernández, Antonio Gómez-Martín, Jeffrey M. Craig, Beatriz Gonzalez-Alzaga, Rebecca J. Schmidt, John F. Dou, Evelyne Muggli, Marina Lacasaña, Martine Vrijheid, Carmen J. Marsit, Margaret R. Karagas, Katri Räikkönen, Luigi Bouchard, Barbara Heude, Loreto Santa-Marina, Mariona Bustamante, Marie-France Hivert, Jose Ramon Bilbao
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
A meta-analysis of pre-pregnancy maternal body mass index (ppBMI) and placental DNA methylation from 2631 mother-child pairs identifies 27 CpG sites associated with ppBMI, providing insight into how maternal obesity could be associated with metabolic
Externí odkaz:
https://doaj.org/article/25f6e68216ef415aa23b5efa7f8762a9
Autor:
Nidhi Ghildayal, Ruby Fore, Sharon M. Lutz, Andres Cardenas, Patrice Perron, Luigi Bouchard, Marie-France Hivert
Publikováno v:
Epigenetics, Vol 17, Iss 7, Pp 808-818 (2022)
Women entering pregnancy with elevated body mass index (BMI) face greater risk of adverse outcomes during pregnancy, delivery, and for their offspring later in life, potentially via epigenetics. If epigenetic programming occurs early during in utero
Externí odkaz:
https://doaj.org/article/6a54202481bd4010b24aaee1b2570f5f
Autor:
Wejdan M. Alenezi, Caitlin T. Fierheller, Corinne Serruya, Timothée Revil, Kathleen K. Oros, Deepak N. Subramanian, Jeffrey Bruce, Dan Spiegelman, Trevor Pugh, Ian G. Campbell, Anne-Marie Mes-Masson, Diane Provencher, William D. Foulkes, Zaki El Haffaf, Guy Rouleau, Luigi Bouchard, Celia M. T. Greenwood, Jiannis Ragoussis, Patricia N. Tonin
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Not all familial ovarian cancer (OC) cases are explained by pathogenic germline variants in known risk genes. A candidate gene approach involving DNA repair pathway genes was applied to identify rare recurring pathogenic variants in familial OC cases
Externí odkaz:
https://doaj.org/article/05d239ab593d4e42b75d51380a913fb1
Autor:
Cécilia Légaré, Andrée-Anne Clément, Véronique Desgagné, Kathrine Thibeault, Frédérique White, Simon-Pierre Guay, Benoit J. Arsenault, Michelle S. Scott, Pierre-Étienne Jacques, Patrice Perron, Renée Guérin, Marie-France Hivert, Luigi Bouchard
Publikováno v:
Reproductive Biology and Endocrinology, Vol 20, Iss 1, Pp 1-13 (2022)
Abstract Background During pregnancy, maternal metabolism undergoes substantial changes to support the developing fetus. Such changes are finely regulated by different mechanisms carried out by effectors such as microRNAs (miRNAs). These small non-co
Externí odkaz:
https://doaj.org/article/fcbd58a1d66b40708e2736977b1c3050