Deferasirox (ICL670A) effectively inhibits oesophageal cancer growth in vitro and in vivo

Autor: Ford, SJ, Obeidy, P, Lovejoy, DB, Bedford, M, Nichols, L, Chadwick, C, Tucker, O, Lui, GYL, Kalinowski, DS, Jansson, PJ, Iqbal, TH, Alderson, D, Richardson, DR, Tselepis, C

Raised intracellular iron has been identified as a potential aetiological factor in the development of several epithelial malignancies, including those of the gastrointestinal tract. The mechanism behind this increase is thought to include disorders

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::af6470c2920516d900a147b17ea5d537
https://europepmc.org/articles/PMC3596639/

Abrogation of RAB27A expression transiently affects melanoma cell proliferation.

Autor: Guo D; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Beaumont KA; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Sharp DM; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Lui GYL; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Weninger W; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Department of Dermatology, Medical University of Vienna, Vienna, Austria.; Discipline of Dermatology, The University of Sydney, Camperdown, NSW, Australia., Haass NK; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Discipline of Dermatology, The University of Sydney, Camperdown, NSW, Australia.; The University of Queensland Diamantina Institute, The University of Queensland, Brisbane, Qld, Australia., Tikoo S; Faculty of Medicine and Health, Immune Imaging Program, Centenary Institute, The University of Sydney, Camperdown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.

Publikováno v: Pigment cell & melanoma research [Pigment Cell Melanoma Res] 2020 Nov; Vol. 33 (6), pp. 889-894. Date of Electronic Publication: 2020 Jun 26.

RAB27A promotes melanoma cell invasion and metastasis via regulation of pro-invasive exosomes.

Autor: Guo D; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Lui GYL; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Lai SL; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia., Wilmott JS; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia., Tikoo S; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Jackett LA; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia.; Royal Prince Alfred Hospital, Camperdown, NSW, Australia., Quek C; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia., Brown DL; The Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Sharp DM; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Kwan RYQ; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Chacon D; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology, Sydney, NSW, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia., Wong JH; Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia.; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pok Fu Lam, Hong Kong., Beck D; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology, Sydney, NSW, Australia.; Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, NSW, Australia., van Geldermalsen M; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Holst J; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia., Thompson JF; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia.; Royal Prince Alfred Hospital, Camperdown, NSW, Australia., Mann GJ; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia.; Centre for Cancer Research, Westmead Institute for Medical Research, The University of Sydney, Westmead, NSW, Australia., Scolyer RA; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.; Melanoma Institute Australia, The University of Sydney, North Sydney, NSW, Australia.; Royal Prince Alfred Hospital, Camperdown, NSW, Australia., Stow JL; The Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Weninger W; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Discipline of Dermatology, The University of Sydney, Camperdown, NSW, Australia.; Department of Dermatology, Royal Prince Alfred Hospital, Camperdown, NSW, Australia., Haass NK; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Discipline of Dermatology, The University of Sydney, Camperdown, NSW, Australia.; The University of Queensland, The University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, QLD, Australia., Beaumont KA; The Centenary Institute, The University of Sydney, Newtown, NSW, Australia.; Sydney Medical School, The University of Sydney, Camperdown, NSW, Australia.

Publikováno v: International journal of cancer [Int J Cancer] 2019 Jun 15; Vol. 144 (12), pp. 3070-3085. Date of Electronic Publication: 2019 Jan 03.

CDK12: an emerging therapeutic target for cancer.

Autor: Lui GYL; Fred Hutchinson Cancer Research Center, Human Biology Division, Seattle, Washington, USA glui@fredhutch.org., Grandori C; SEngine Precision Medicine, Seattle, Washington, USA., Kemp CJ; Fred Hutchinson Cancer Research Center, Human Biology Division, Seattle, Washington, USA.

Publikováno v: Journal of clinical pathology [J Clin Pathol] 2018 Nov; Vol. 71 (11), pp. 957-962. Date of Electronic Publication: 2018 Aug 13.