Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Luhua Shen"'
Autor:
Philip D Greenberg, Christopher A Klebanoff, Kim Nguyen, Gary Shapiro, Joshua Francis, Cheryl Black, Anthony Thomas, Meghan D Storlie, Allison P Drain, Nicholas Rouillard, Nathaniel Swanson, Santosh Narayan, Tyler Warner, Nicole Danek, Ken Gareau, James Parsons, Jinsheng Liang, Luhua Shen, Tanya Tetrault, Vince Nguyen, Iqraa Priyata, Sarah Vidyasagar, Xingyue He, Patrick J Browne, Rebecca C Lamothe, Gregory J Cost, Thomas M Schmitt, Smita S Chandran, Ankit Gupta, Damien Hallet, Loic Vincent
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/7bb2d3e90f9f44b38eb43af51b8a6f42
Autor:
Philip D Greenberg, Christopher A Klebanoff, Kim Nguyen, Gary Shapiro, Joshua Francis, Cheryl Black, Anthony Thomas, Meghan D Storlie, Allison P Drain, Nicholas Rouillard, Nathaniel Swanson, Santosh Narayan, Tyler Warner, Nicole Danek, Ken Gareau, James Parsons, Jinsheng Liang, Luhua Shen, Tanya Tetrault, Vince Nguyen, Iqraa Priyata, Sarah Vidyasagar, Xingyue He, Patrick J Browne, Rebecca C Lamothe, Gregory J Cost, Thomas M Schmitt, Smita S Chandran, Ankit Gupta, Damien Hallet, Loic Vincent
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/cf7222b351e14e179116c6bbe6cf91f4
Autor:
Elizabeth Carideo Cunniff, Yosuke Sato, Doanh Mai, Vicky A. Appleman, Shinji Iwasaki, Vihren Kolev, Atsushi Matsuda, Judy Shi, Michiyo Mochizuki, Masato Yoshikawa, Jian Huang, Luhua Shen, Satyajeet Haridas, Vaishali Shinde, Chris Gemski, Emily R. Roberts, Omid Ghasemi, Hojjat Bazzazi, Saurabh Menon, Tary Traore, Pu Shi, Tennille D. Thelen, Joseph Conlon, Adnan O. Abu-Yousif, Christopher Arendt, Michael H. Shaw, Masanori Okaniwa
Publikováno v:
Cancer Research Communications. 2:489-502
Oncology therapies targeting the immune system have improved patient outcomes across a wide range of tumor types, but resistance due to an inadequate T-cell response in a suppressive tumor microenvironment (TME) remains a significant problem. New the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f15976fac4916e2a443db60d3b3b36d
https://doi.org/10.1158/2767-9764.crc-21-0161
https://doi.org/10.1158/2767-9764.crc-21-0161
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary methods and results: The supplementary methods describe: 1) the chemical synthesis and characterization of TAK-676, inclusive of TAK-676 chemical structure, purification chromatogram and NMR characterization; 2) details regarding STING
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931bb15e27a36d43a39bd54192992a77
https://doi.org/10.1158/2767-9764.22544573
https://doi.org/10.1158/2767-9764.22544573
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Oncology therapies targeting the immune system have improved patient outcomes across a wide range of tumor types, but resistance due to an inadequate T-cell response in a suppressive tumor microenvironment (TME) remains a significant problem. New the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba8980eb34badc6a19f61bbce026e67
https://doi.org/10.1158/2767-9764.c.6550691
https://doi.org/10.1158/2767-9764.c.6550691
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary tables: Supplementary Table 1 describes where cells were obtained from and details of authentication and mycoplasma testing dates. Supplementary Table 2 shows TAK-676 potency in cynomolgus monkey, human, mouse, and rat STING via time-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bc816185704d6e9271927a182bdb34f
https://doi.org/10.1158/2767-9764.22544570
https://doi.org/10.1158/2767-9764.22544570
Autor:
Masanori Okaniwa, Michael H. Shaw, Christopher Arendt, Adnan O. Abu-Yousif, Joseph Conlon, Tennille D. Thelen, Pu Shi, Tary Traore, Saurabh Menon, Hojjat Bazzazi, Omid Ghasemi, Emily R. Roberts, Chris Gemski, Vaishali Shinde, Satyajeet Haridas, Luhua Shen, Jian Huang, Masato Yoshikawa, Michiyo Mochizuki, Judy Shi, Atsushi Matsuda, Vihren Kolev, Shinji Iwasaki, Vicky A. Appleman, Doanh Mai, Yosuke Sato, Elizabeth Carideo Cunniff
Supplementary figures: Supplementary Figure 1 shows cell viability of human monocyte-derived dendric cells and mouse bone marrow dendritic cells. Supplementary Figure 2 shows mean plasma and tumor concentration-time curves of TAK-676 in BALB/C mice (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f557c397f065d58fee34ecc2828d809
https://doi.org/10.1158/2767-9764.22544576
https://doi.org/10.1158/2767-9764.22544576
Autor:
Alexandra E. Gould, Courtney Cullis, Lee Hong Myung, David Lok, Rachel E. Gershman, Scott R. Rowland, Miho Mizutani, Dave Janowick, Gipson Krista E, Vihren Kolev, Robert J. Griffin, Joe Conlon, Steve Stroud, Akito Hata, Jeffrey Ciavarri, Dylan Bradley England, Cardin David P, Sandeep Pusalkar, Paul D. Greenspan, Adnan O Abu-Yousif, Jenna Malley, Doanh Mai, Michael Shaw, Ji Zhang, Robert J. Skene, Hu Zhigen, Matthew A. Jones, Atsushi Matsuda, Shih-Chung Huang, Nina Molchanova, Xu Tianlin, Jian Huang, He Xu, Stepan Vyskocil, Nanda Gulavita, Francois Soucy, Gang Li, Yongbo Hu, Liting Ma, Steven P. Langston, Zhan Shi, Christelle C. Renou, Luhua Shen, Sean Harrison, Elise Nunes, Kenneth M. Gigstad, Yosuke Sato, Hirotake Mizutani
Publikováno v:
Journal of Medicinal Chemistry. 64:6902-6923
Stimulator of Interferon Genes (STING) plays an important role in innate immunity by inducing type I interferon production upon infection with intracellular pathogens. STING activation can promote increased T-cell activation and inflammation in the t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f642868da1ca20f638998dc8a616442f
https://doi.org/10.1021/acs.jmedchem.1c00374
https://doi.org/10.1021/acs.jmedchem.1c00374
Autor:
Brian Krieger, Richard Nicoletti, Qing Liu, Julie Tao, Ruoji Wang, Jie Lin, Zakir Siddiquee, Luhua Shen, Bin Feng, Solly Weiler, Elizabeth K. Mazsa, M. Isabel Chiu, Zhigang Weng, Lorena Lerner, Lucia Huang, Jeno Gyuris, William Winston, Antonio Vigano
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle. 7:467-482
Background Cancer associated cachexia affects the majority of cancer patients during the course of the disease and thought to be directly responsible for about a quarter of all cancer deaths. Current evidence suggests that a pro-inflammatory state ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9e2e6e331c64e55a9910d78219976f9
https://doi.org/10.1002/jcsm.12077
https://doi.org/10.1002/jcsm.12077
Autor:
Ronald J Beyers, Luhua Shen, Patrick A. Helm, Frederick H. Epstein, Vincent Jacques, Christopher M. Kramer, Yaqin Xu, Brent A. French, Peter Caravan, R. Jack Roy
Publikováno v:
Radiology. 247:788-796
To prospectively evaluate a gadolinium-based collagen-targeting contrast agent, EP-3533, for in vivo magnetic resonance (MR) imaging of myocardial fibrosis in a mouse model of healed myocardial infarction (MI).All procedures were performed in accorda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11d7582092b3230784c1d4eb34339577
https://doi.org/10.1148/radiol.2473070975
https://doi.org/10.1148/radiol.2473070975