Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Luhan T Zhou"'
Autor:
Ewa K Bomba-Warczak, Karen M Velez, Luhan T Zhou, Christelle Guillermier, Seby Edassery, Matthew L Steinhauser, Jeffrey N Savas, Francesca E Duncan
Publikováno v:
eLife, Vol 13 (2024)
The mechanisms contributing to age-related deterioration of the female reproductive system are complex, however aberrant protein homeostasis is a major contributor. We elucidated exceptionally stable proteins, structures, and macromolecules that pers
Externí odkaz:
https://doaj.org/article/6aa92de16b3c4bd9af87d1fb9f1b6b64
Autor:
Atsuko Kusuhara, Elnur Babayev, Luhan T. Zhou, Vijay P. Singh, Jennifer L. Gerton, Francesca E. Duncan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Egg quality dictates fertility outcomes, and although there is a well-documented decline with advanced reproductive age, how it changes during puberty is less understood. Such knowledge is critical, since advances in Assisted Reproductive Technologie
Externí odkaz:
https://doaj.org/article/43799be5c875431cbc20a55f88ad5b9f
Autor:
Shweta S. Dipali, Christina R. Ferreira, Luhan T. Zhou, Michele T. Pritchard, Francesca E. Duncan
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-13 (2019)
Abstract Background Reproductive aging is a robust phenotype that occurs in all females and is characterized by a significant reduction in gamete quantity and quality, which can have negative consequences on both endocrine function and fertility. Age
Externí odkaz:
https://doaj.org/article/6c0b3e78de6343e282fbf6a877455f20
Autor:
Derek G. Epiney, Charlotte Salameh, Deirdre Cassidy, Luhan T. Zhou, Joshua Kruithof, Rolan Milutinović, Tomas S. Andreani, Aaron E. Schirmer, Elyse Bolterstein
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1868 (2021)
As organisms age, their resistance to stress decreases while their risk of disease increases. This can be shown in patients with Werner syndrome (WS), which is a genetic disease characterized by accelerated aging along with increased risk of cancer a
Externí odkaz:
https://doaj.org/article/c4e31a2da715405a889d2d808fc3ccdb
Autor:
Madison Q. Gowett, Sarah S. Perry, Raveena Aggarwal, Luhan T. Zhou, Mary Ellen Pavone, Francesca E. Duncan, W. Susan Cheng
Publikováno v:
Journal of Assisted Reproduction and Genetics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d5befee8b7d1a5bce8198d92b5f578a
https://doi.org/10.1007/s10815-023-02801-3
https://doi.org/10.1007/s10815-023-02801-3
Autor:
Cecilia E. Villanueva, Wendena S. Parkes, Michele T. Pritchard, Francesca E. Duncan, Farners Amargant, Luhan T. Zhou
Publikováno v:
Genes
Volume 12
Issue 8
Genes, Vol 12, Iss 1186, p 1186 (2021)
Volume 12
Issue 8
Genes, Vol 12, Iss 1186, p 1186 (2021)
The extracellular matrix (ECM) is a major component of the ovarian stroma. Collagen and hyaluronan (HA) are critical ovarian stromal ECM molecules that undergo age-dependent changes in the mouse and human. How these matrix components are regulated an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9c464fe60bcc7c5a8834b589e5d96e
http://europepmc.org/articles/PMC8392036
http://europepmc.org/articles/PMC8392036
Autor:
Raveena Aggarwal, Madison Q. Gowett, Sarah S. Perry, Mary Ellen Pavone, Susan Cheng, Luhan T. Zhou, Francesca E. Duncan
Publikováno v:
Fertility and Sterility. 116:e406-e407
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f3744736a1ffd1f2e460a5389b5ba27
https://doi.org/10.1016/j.fertnstert.2021.07.1086
https://doi.org/10.1016/j.fertnstert.2021.07.1086
Autor:
Francesca E. Duncan, Luhan T. Zhou, Adam R. Hall, Wendena S. Parkes, Qing Tu, Farners Amargant, Michele T. Pritchard, Sharrón L. Manuel, Gajendra S. Shekhawat, Mary Ellen Pavone, Felipe Rivas, Jennifer E. Rowley, Cecilia E. Villanueva, Jian Jun Wei, Jessica E. Hornick
Publikováno v:
Aging Cell
Fibrosis is a hallmark of aging tissues which often leads to altered architecture and function. The ovary is the first organ to show overt signs of aging, including increased fibrosis in the ovarian stroma. How this fibrosis affects ovarian biomechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6ceb1833ffa4d5280435e8a06b04d6
https://doi.org/10.1111/acel.13259
https://doi.org/10.1111/acel.13259
Autor:
Benjamin C. Owen, Hunter B. Rogers, Emily Zaniker, Saman Shafaie, Teresa K. Woodruff, Francesca E. Duncan, Atsuko Kusuhara, Luhan T. Zhou
Publikováno v:
Chemosphere
We recently engineered the first female reproductive tract on a chip (EVATAR), to enable sex-based ex vivo research. To increase the scalability and accessibility of EVATAR, we turned to 3D printing (3DP) technologies, selecting two biocompatible 3DP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77556eb8e57aa058b6456f1120afffc
https://pubmed.ncbi.nlm.nih.gov/33515896
https://pubmed.ncbi.nlm.nih.gov/33515896
Autor:
Francesca E. Duncan, Michele T. Pritchard, Jamie N. Mara, Rebecca Ayiku, Megan J. Larmore, Brian Johnson, Luhan T. Zhou, Farners Amargant
Publikováno v:
Aging (Albany NY)
Aging is associated with reduced tissue remodeling efficiency and increased fibrosis, characterized by excess collagen accumulation and altered matrix degradation. Ovulation, the process by which an egg is released from the ovary, is one of the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da09a7150ea89d074af0f08c9948ea3
https://pubmed.ncbi.nlm.nih.gov/32407290
https://pubmed.ncbi.nlm.nih.gov/32407290