Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Lufeng Zheng"'
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background The roles of the transcriptional factor SIX2 have been identified in several tumors. However, its roles in gastric cancer (GC) progression have not yet been revealed. Our objective is to explore the impact and underlying mechanism
Externí odkaz:
https://doaj.org/article/81a0d4eb0d2645d2940193d1b2067b0d
Publikováno v:
Journal of Pharmaceutical Analysis, Vol 14, Iss 8, Pp 100984- (2024)
Anlotinib has strong antiangiogenic effects and leads to vessel normalization. However, the “window period” characteristic in regulating vessel normalization by anlotinib cannot fully explain the long-term survival benefits achieved through combi
Externí odkaz:
https://doaj.org/article/964f05ed0c384e1cb3f5f94a220b65aa
Autor:
Xuedan Han, Hai Qin, Yu Lu, Haitao Chen, Zhengdong Yuan, Yiwen Zhang, Xuena Yang, Lufeng Zheng, Simin Yan
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34015- (2024)
While strides in cancer treatment continue to advance, the enduring challenges posed by cancer metastasis and recurrence persist as formidable contributors to the elevated mortality rates observed in cancer patients. Among the multifaceted factors im
Externí odkaz:
https://doaj.org/article/7cc3b67e066a497ab809e9c991994f55
Autor:
Zhenyan Miao, Jifei Li, Yu Wang, Mingqin Shi, Xiao Gu, Xuanqi Zhang, Fang Wei, Xinying Tang, Lufeng Zheng, Yingying Xing
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-19 (2023)
Abstract Background Targeted drugs are not quite effective for prolonging the survival of patients with gastric cancer due to off-target effects as well as tumor immune escape mechanisms. Circular RNAs widely exist in tumor regions as biomarkers and
Externí odkaz:
https://doaj.org/article/25044016f4b34a1e8c8c2226466a919f
Autor:
Qianqian Guo, Yi Zhou, Tianyuan Xie, Yin Yuan, Huilong Li, Wanjin Shi, Lufeng Zheng, Xiaoman Li, Wenzhou Zhang
Publikováno v:
Genes and Diseases, Vol 11, Iss 3, Pp 101043- (2024)
There are few tumor cell subpopulations with stem cell characteristics in tumor tissue, defined as cancer stem cells (CSCs) or cancer stem-like cells (CSLCs), which can reconstruct neoplasms with malignant biological behaviors such as invasiveness vi
Externí odkaz:
https://doaj.org/article/63d92acf8d93466f9d92385aa5cc8f90
Publikováno v:
Genes and Diseases, Vol 8, Iss 6, Pp 759-768 (2021)
Metastasis, is a development of secondary tumor growths at a distance from the primary site, and closely related to poor prognosis and mortality. However, there is still no effective treatment for metastatic cancer. Therefore, there is an urgent need
Externí odkaz:
https://doaj.org/article/8aea34a8a5a14db18021ffc4ae0f6a1f
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Tripartite motif (TRIM) containing proteins are a class of E3 ubiquitin ligases, which are critically implicated in the occurrence and development of tumors. They can function through regulating various aspects of tumors, such as tumor proliferation,
Externí odkaz:
https://doaj.org/article/d9cc9d1c3ba3479e88b3eacebb1c972f
Autor:
Haiwei Ni, Hai Qin, Cheng Sun, Yichen Liu, Guojing Ruan, Qianqian Guo, Tao Xi, Yingying Xing, Lufeng Zheng
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-17 (2021)
Abstract Background Gastric cancer stem cells (CSCs) are the main causes of metastasis and drug resistance. We previously indicated that miR-375 can inhibit Helicobacter pylori-induced gastric carcinogenesis; here, we aim to explore the effects and m
Externí odkaz:
https://doaj.org/article/068497ea5ac049fda9cd361c4a807a28
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Breast cancer is the most common malignancy in women and has a high incidence rate and mortality. Abnormal regulation of gene expression plays an important role in breast cancer occurrence and development. RNA-binding proteins (RBPs) are one kind of
Externí odkaz:
https://doaj.org/article/1ca02816151f472599fb7d8b83096e09
Autor:
Qianqian Guo, Ting Wang, Yue Yang, Lanlan Gao, Qiong Zhao, Wenzhou Zhang, Tao Xi, Lufeng Zheng
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 21, Iss , Pp 527-541 (2020)
Transcription factor Yin Yang 1 (YY1) is upregulated in multiple tumors and plays essential roles in tumor proliferation and metastasis. However, the function of YY1 in breast cancer stemness remains unclear. Herein, we found that YY1 expression was
Externí odkaz:
https://doaj.org/article/6c532d1bb90345508fb4a7d4b9ff57ed