Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lufei Shan"'
Autor:
Yu Luo, Cameron H Good, Oscar Diaz-Ruiz, YaJun Zhang, Alexander F Hoffman, Lufei Shan, Serena Y Kuang, Nasir Malik, Vladimir I Chefer, Andreas C Tomac, Carl R Lupica, Cristina M Bäckman
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12141 (2010)
The initiation of behavioral sensitization to cocaine and other psychomotor stimulants is thought to reflect N-methyl-D-aspartate receptor (NMDAR)-mediated synaptic plasticity in the mesolimbic dopamine (DA) circuitry. The importance of drug induced
Externí odkaz:
https://doaj.org/article/6320367ff1ae43188ebccaaaa6504c2f
Autor:
Oscar Diaz-Ruiz, Agustin Zapata, Lufei Shan, YaJun Zhang, Andreas C Tomac, Nasir Malik, Fidel de la Cruz, Cristina M Bäckman
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7027 (2009)
The widespread distribution of the tumor suppressor PTEN in the nervous system suggests a role in a broad range of brain functions. PTEN negatively regulates the signaling pathways initiated by protein kinase B (Akt) thereby regulating signals for gr
Externí odkaz:
https://doaj.org/article/cbadc34e8d854ad0bd3099685c174ccf
Autor:
Carl R. Lupica, Cristina M. Bäckman, Nasir Malik, Alexander F. Hoffman, Lars Olson, Kyounghee Huh, Lufei Shan, YaJun Zhang, Oscar Diaz-Ruiz, Barry J. Hoffer, Ann-Charlotte Granholm
Publikováno v:
Brain
Clinical trials in Parkinson’s disease have shown that transplants of embryonic mesencephalic dopamine neurons form new functional connections within the host striatum, but the therapeutic benefits have been highly variable. One obstacle has been p
Autor:
Sara Arezou Sarabi, Cristina M. Bäckman, Lufei Shan, Howard J. Federoff, Barry J. Hoffer, Yu Luo
Publikováno v:
Brain Research. 1302:42-53
We previously reported the identification of the Nurr1 interacting protein (NuIP) that was demonstrated to modulate the transcriptional activity of Nurr1, the orphan nuclear receptor required for midbrain dopaminergic neuron differentiation. NuIP was
Autor:
Oscar Diaz, Lufei Shan, Barry J. Hoffer, Bruce Ladenheim, YaJun Zhang, Yung Hsiao Chiang, Lars Olson, Cristina M. Bäckman, Jean Lud Cadet
In Parkinson’s disease, the efficacy of l-Dopa treatment changes over time, as dyskinesias emerge with previously beneficial doses. Using MitoPark mice, that models mitochondrial failure in dopamine (DA) neurons and mimics the progressive loss of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87a4c1cef4c62f655a4ee040270ac04
https://europepmc.org/articles/PMC4710145/
https://europepmc.org/articles/PMC4710145/
Autor:
Juan C. Troncoso, Lufei Shan, Barry J. Hoffer, Paul Vonsatel, Ya Jun Zhang, Andreas C. Tomac, Cristina M. Bäckman, Sherry Leonard
Publikováno v:
Molecular and Cellular Endocrinology. 252:160-166
Glial cell line-derived neurotrophic factor (GDNF), a member of the transforming growth factor-beta superfamily, is a potent trophic factor for dopaminergic neurons of the ventral midbrain, which are known to degenerate during Parkinson's disease (PD
Autor:
Lufei Shan, Oscar Diaz-Ruiz, Nasir Malik, Yu Luo, Cameron H. Good, Vladimir I. Chefer, YaJun Zhang, Cristina M. Bäckman, Andreas C. Tomac, Serena Y. Kuang, Alexander F. Hoffman, Carl R. Lupica
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12141 (2010)
PLoS ONE
PLoS ONE
Background The initiation of behavioral sensitization to cocaine and other psychomotor stimulants is thought to reflect N-methyl-D-aspartate receptor (NMDAR)-mediated synaptic plasticity in the mesolimbic dopamine (DA) circuitry. The importance of dr
Autor:
Nasir Malik, Andreas C. Tomac, Lufei Shan, Cristina M. Bäckman, Fidel de la Cruz, YaJun Zhang, Agustin Zapata, Oscar Diaz-Ruiz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 9, p e7027 (2009)
PLoS ONE, Vol 4, Iss 9, p e7027 (2009)
The widespread distribution of the tumor suppressor PTEN in the nervous system suggests a role in a broad range of brain functions. PTEN negatively regulates the signaling pathways initiated by protein kinase B (Akt) thereby regulating signals for gr
Autor:
Cristina M. Bäckman, Nasir Malik, YaJun Zhang, Andreas C. Tomac, Lufei Shan, Barry J. Hoffer, Heiner Westphal
Publikováno v:
Journal of neuroscience methods. 176(1)
Inducible Cre recombinase systems have been developed to bypass initial lethal phenotypes and to provide access to later embryonic or adult phenotypes. Here we describe the generation of a recombinant mouse that combines a tetracycline dependent swit
Publikováno v:
Journal of neuroscience research. 85(4)
A real-time quantitative PCR approach was used to quantify mRNA levels corresponding to the neuropeptides enkephalin, dynorphin, and the 67-kDa isoform of glutamic acid decarboxylase (GAD67) in the human putamen from young and aged individuals as wel