Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Lufei Shan"'
Autor:
Yu Luo, Cameron H Good, Oscar Diaz-Ruiz, YaJun Zhang, Alexander F Hoffman, Lufei Shan, Serena Y Kuang, Nasir Malik, Vladimir I Chefer, Andreas C Tomac, Carl R Lupica, Cristina M Bäckman
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12141 (2010)
The initiation of behavioral sensitization to cocaine and other psychomotor stimulants is thought to reflect N-methyl-D-aspartate receptor (NMDAR)-mediated synaptic plasticity in the mesolimbic dopamine (DA) circuitry. The importance of drug induced
Externí odkaz:
https://doaj.org/article/6320367ff1ae43188ebccaaaa6504c2f
Autor:
Oscar Diaz-Ruiz, Agustin Zapata, Lufei Shan, YaJun Zhang, Andreas C Tomac, Nasir Malik, Fidel de la Cruz, Cristina M Bäckman
Publikováno v:
PLoS ONE, Vol 4, Iss 9, p e7027 (2009)
The widespread distribution of the tumor suppressor PTEN in the nervous system suggests a role in a broad range of brain functions. PTEN negatively regulates the signaling pathways initiated by protein kinase B (Akt) thereby regulating signals for gr
Externí odkaz:
https://doaj.org/article/cbadc34e8d854ad0bd3099685c174ccf
Autor:
Carl R. Lupica, Cristina M. Bäckman, Nasir Malik, Alexander F. Hoffman, Lars Olson, Kyounghee Huh, Lufei Shan, YaJun Zhang, Oscar Diaz-Ruiz, Barry J. Hoffer, Ann-Charlotte Granholm
Publikováno v:
Brain
Clinical trials in Parkinson’s disease have shown that transplants of embryonic mesencephalic dopamine neurons form new functional connections within the host striatum, but the therapeutic benefits have been highly variable. One obstacle has been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9240faf348b425d4dc744aa7cfae18a0
https://doi.org/10.1093/brain/aws196
https://doi.org/10.1093/brain/aws196
Autor:
Sara Arezou Sarabi, Cristina M. Bäckman, Lufei Shan, Howard J. Federoff, Barry J. Hoffer, Yu Luo
Publikováno v:
Brain Research. 1302:42-53
We previously reported the identification of the Nurr1 interacting protein (NuIP) that was demonstrated to modulate the transcriptional activity of Nurr1, the orphan nuclear receptor required for midbrain dopaminergic neuron differentiation. NuIP was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807d48754549e83c76731ba1624b7e7e
https://doi.org/10.1016/j.brainres.2009.09.026
https://doi.org/10.1016/j.brainres.2009.09.026
Autor:
Oscar Diaz, Lufei Shan, Barry J. Hoffer, Bruce Ladenheim, YaJun Zhang, Yung Hsiao Chiang, Lars Olson, Cristina M. Bäckman, Jean Lud Cadet
In Parkinson’s disease, the efficacy of l-Dopa treatment changes over time, as dyskinesias emerge with previously beneficial doses. Using MitoPark mice, that models mitochondrial failure in dopamine (DA) neurons and mimics the progressive loss of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87a4c1cef4c62f655a4ee040270ac04
https://europepmc.org/articles/PMC4710145/
https://europepmc.org/articles/PMC4710145/
Autor:
Juan C. Troncoso, Lufei Shan, Barry J. Hoffer, Paul Vonsatel, Ya Jun Zhang, Andreas C. Tomac, Cristina M. Bäckman, Sherry Leonard
Publikováno v:
Molecular and Cellular Endocrinology. 252:160-166
Glial cell line-derived neurotrophic factor (GDNF), a member of the transforming growth factor-beta superfamily, is a potent trophic factor for dopaminergic neurons of the ventral midbrain, which are known to degenerate during Parkinson's disease (PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ceaf6084ef54b8cdd2377a44509e93c
https://doi.org/10.1016/j.mce.2006.03.013
https://doi.org/10.1016/j.mce.2006.03.013
Autor:
Bruce Ladenheim, YaJun Zhang, Carl R. Lupica, Lufei Shan, Nasir Malik, Alicia Brusco, Adriana Tagliaferro, Cristina M. Bäckman, Alexander F. Hoffman, Oscar Diaz-Ruiz, Jean Lud Cadet
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
In the present study, we analyzed mice with a targeted deletion of β-catenin in DA neurons (DA-βcat KO mice) to address the functional significance of this molecule in the shaping of synaptic responses associated with motor learning and following e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28050951c28e76c0167d8321e3a3e1b3
http://learnmem.cshlp.org/content/19/8/341
http://learnmem.cshlp.org/content/19/8/341
Autor:
Lufei Shan, Oscar Diaz-Ruiz, Nasir Malik, Yu Luo, Cameron H. Good, Vladimir I. Chefer, YaJun Zhang, Cristina M. Bäckman, Andreas C. Tomac, Serena Y. Kuang, Alexander F. Hoffman, Carl R. Lupica
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12141 (2010)
PLoS ONE
PLoS ONE
Background The initiation of behavioral sensitization to cocaine and other psychomotor stimulants is thought to reflect N-methyl-D-aspartate receptor (NMDAR)-mediated synaptic plasticity in the mesolimbic dopamine (DA) circuitry. The importance of dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6d473a82319153a690b9e08bfad0a6
http://europepmc.org/articles/PMC2922329?pdf=render
http://europepmc.org/articles/PMC2922329?pdf=render
Autor:
Nasir Malik, Andreas C. Tomac, Lufei Shan, Cristina M. Bäckman, Fidel de la Cruz, YaJun Zhang, Agustin Zapata, Oscar Diaz-Ruiz
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 9, p e7027 (2009)
PLoS ONE, Vol 4, Iss 9, p e7027 (2009)
The widespread distribution of the tumor suppressor PTEN in the nervous system suggests a role in a broad range of brain functions. PTEN negatively regulates the signaling pathways initiated by protein kinase B (Akt) thereby regulating signals for gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45afda856665f94d5032f947537694a5
https://pubmed.ncbi.nlm.nih.gov/19750226
https://pubmed.ncbi.nlm.nih.gov/19750226
Autor:
Cristina M. Bäckman, Nasir Malik, YaJun Zhang, Andreas C. Tomac, Lufei Shan, Barry J. Hoffer, Heiner Westphal
Publikováno v:
Journal of neuroscience methods. 176(1)
Inducible Cre recombinase systems have been developed to bypass initial lethal phenotypes and to provide access to later embryonic or adult phenotypes. Here we describe the generation of a recombinant mouse that combines a tetracycline dependent swit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ae372d60f23ee65314c3e87f1be11e
https://pubmed.ncbi.nlm.nih.gov/18801387
https://pubmed.ncbi.nlm.nih.gov/18801387