Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase

Autor: Leuenberger, Tina, Pfueller, Caspar F, Luessi, Felix, Bendix, Ivo, Paterka, Magdalena, Prozorovski, Timour, Treue, Denise, Luenstedt, Sarah, Herz, Josephine, Siffrin, Volker, Infante-Duarte, Carmen, Zipp, Frauke, Waiczies, Sonia

Publikováno v: PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e100871 (2014)

The maturation status of dendritic cells determines whether interacting T cells are activated or if they become tolerant. Previously we could induce T cell tolerance by applying a 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase inhibitor (HMGCRI)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2767689271167ba762ecf1981cfc96
http://edoc.mdc-berlin.de/14194/1/14194oa.pdf

Modulation of dendritic cell immunobiology via inhibition of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase.

Autor: Leuenberger T; Department of Neurology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany; Max Delbrueck Center for Molecular Medicine Berlin-Buch, Berlin, Germany., Pfueller CF; NeuroCure Clinical Research Center, Charité University Medicine Berlin, Berlin, Germany., Luessi F; Department of Neurology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany., Bendix I; Department of Pediatrics I/Neonatology, University Hospital Essen, Essen, Germany., Paterka M; Department of Neurology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany; Max Delbrueck Center for Molecular Medicine Berlin-Buch, Berlin, Germany., Prozorovski T; Department of Neurology, Heinrich-Heine-University, Duesseldorf, Germany., Treue D; Institute of Pathology, Charité University Medicine Berlin, Berlin, Germany., Luenstedt S; Max Delbrueck Center for Molecular Medicine Berlin-Buch, Berlin, Germany., Herz J; Department of Pediatrics I/Neonatology, University Hospital Essen, Essen, Germany., Siffrin V; Department of Neurology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany; Max Delbrueck Center for Molecular Medicine Berlin-Buch, Berlin, Germany., Infante-Duarte C; Institute for Medical Immunology, Charité University Medicine Berlin, Berlin, Germany., Zipp F; Department of Neurology, Focus Program Translational Neuroscience (FTN), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg-University of Mainz, Mainz, Germany; Max Delbrueck Center for Molecular Medicine Berlin-Buch, Berlin, Germany., Waiczies S; Berlin Ultrahigh Field Facility (B.U.F.F.), Max Delbrück Center for Molecular Medicine, Berlin, Germany.

Publikováno v: PloS one [PLoS One] 2014 Jul 11; Vol. 9 (7), pp. e100871. Date of Electronic Publication: 2014 Jul 11 (Print Publication: 2014).