Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents.

Autor: Corfu AI; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Santarem N; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.; Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal., Luelmo S; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.; Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal., Mazza G; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milan, Italy., Greco A; Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy., Altomare A; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Ferrario G; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Nasta G; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Keminer O; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, Germany.; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases (CIMD), Schnackenburgallee 114, 22525 Hamburg, Germany., Aldini G; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Tamborini L; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Basilico N; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Via Pascal 36, 20133 Milan, Italy., Parapini S; Department of Biomedical Sciences for Health, University of Milan, Via Pascal 36, 20133 Milan, Italy., Gul S; Fraunhofer Institute for Translational Medicine and Pharmacology (ITMP), Schnackenburgallee 114, 22525 Hamburg, Germany.; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases (CIMD), Schnackenburgallee 114, 22525 Hamburg, Germany., Cordeiro-da-Silva A; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.; Department of Biological Sciences, Faculty of Pharmacy, University of Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal., Conti P; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy., Borsari C; Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, 20133 Milan, Italy.

Publikováno v: ACS infectious diseases [ACS Infect Dis] 2024 Jun 14; Vol. 10 (6), pp. 2222-2238. Date of Electronic Publication: 2024 May 08.

Exploring the potential role of four Rhizophagus irregularis nuclear effectors: opportunities and technical limitations.

Autor: Aparicio Chacón MV; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Hernández Luelmo S; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Devlieghere V; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Robichez L; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Leroy T; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Stuer N; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., De Keyser A; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Ceulemans E; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Goossens A; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Goormachtig S; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium., Van Dingenen J; Department of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.; Center for Plant Systems Biology, VIB, Gent, Belgium.

Publikováno v: Frontiers in plant science [Front Plant Sci] 2024 Apr 24; Vol. 15, pp. 1384496. Date of Electronic Publication: 2024 Apr 24 (Print Publication: 2024).

Design, synthesis and biological evaluation of antiparasitic dinitroaniline-ether phospholipid hybrids.

Autor: Roussaki M; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: mroussaki@eie.gr., Magoulas GE; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: gmagoulas@eie.gr., Fotopoulou T; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: tfotop@eie.gr., Santarem N; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal. Electronic address: santarem@ibmc.up.pt., Barrias E; Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho s/n, Ilha do Fundão, 21941-900 Rio de Janeiro, Brazil. Electronic address: emilebarrias@gmail.com., Pöhner I; School of Pharmacy, University of Eastern Finland, Kuopio, Finland. Electronic address: ina.pohner@uef.fi., Luelmo S; i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal. Electronic address: sluelmo@i3s.up.pt., Afroudakis P; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: pafroudakischem@yahoo.gr., Georgikopoulou K; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: k.georgikopoulou@access-one.gr., Nevado PT; Bernhard Nocht Institute for Tropical Medicine, Leishmania Genetics Group, Bernhard Nocht St 74, D-20359 Hamburg, Germany. Electronic address: paloma.tejera.nevado@gu.se., Eick J; Bernhard Nocht Institute for Tropical Medicine, Leishmania Genetics Group, Bernhard Nocht St 74, D-20359 Hamburg, Germany. Electronic address: Julia.Eick@gmx.de., Bifeld E; Bernhard Nocht Institute for Tropical Medicine, Leishmania Genetics Group, Bernhard Nocht St 74, D-20359 Hamburg, Germany. Electronic address: eugeniabifeld@gmail.com., Corral MJ; Department of Animal Health, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain. Electronic address: mjcorralcaridad@gmail.com., Jiménez-Antón MD; Department of Animal Health, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain. Electronic address: mariadolores.jimenez@ucm.es., Ellinger B; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Hamburg, Germany. Electronic address: Bernhard.Ellinger@itmp.fraunhofer.de., Kuzikov M; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Hamburg, Germany. Electronic address: Maria.Kuzikov@itmp.fraunhofer.de., Fragiadaki I; University of Crete, Faculty of Medicine, Department of Clinical Microbiology and Microbial Pathogenesis, Voutes University Campus, 70013 Heraklion, Crete, Greece. Electronic address: fragiada@med.uoc.gr., Scoulica E; University of Crete, Faculty of Medicine, Department of Clinical Microbiology and Microbial Pathogenesis, Voutes University Campus, 70013 Heraklion, Crete, Greece. Electronic address: e.scoulica@uoc.gr., Gul S; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Hamburg, Germany; Fraunhofer Cluster of Excellence for Immune-Mediated Diseases CIMD, Hamburg, Germany. Electronic address: Sheraz.Gul@itmp.fraunhofer.de., Clos J; Bernhard Nocht Institute for Tropical Medicine, Leishmania Genetics Group, Bernhard Nocht St 74, D-20359 Hamburg, Germany. Electronic address: clos@bnitm.de., Prousis KC; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: kyrprous@eie.gr., Torrado JJ; Department of Pharmaceutics and Food Technology, Complutense University of Madrid, 28240 Madrid, Spain. Electronic address: torrado1@farm.ucm.es., Alunda JM; Department of Animal Health, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, 28040 Madrid, Spain. Electronic address: jmalunda@ucm.es., Wade RC; Molecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies (HITS), D-69118 Heidelberg, Germany; Center for Molecular Biology (ZMBH), DKFZ-ZMBH Alliance, and Interdisciplinary Center for Scientific Computing (IWR), Heidelberg University, D-69120 Heidelberg, Germany. Electronic address: rebecca.wade@h-its.org., de Souza W; Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Avenida Carlos Chagas Filho s/n, Ilha do Fundão, 21941-900 Rio de Janeiro, Brazil. Electronic address: wsouza@biof.ufrj.br., Cordeiro da Silva A; IBMC-Instituto de Biologia Molecular e Celular, Parasite Disease Group, Porto, Portugal; Instituto Nacional de Ciência e Tecnologia em Biologia Estrutural e Bioimagens, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil; Departmento de Ciências Biológicas, Faculdade de Farmácia, Universidade do Porto, Porto, Portugal. Electronic address: cordeiro@ibmc.up.pt., Calogeropoulou T; National Hellenic Research Foundation, Institute of Chemical Biology, 48 Vassileos Constantinou Avenue, 11635 Athens, Greece. Electronic address: tcalog@eie.gr.

Publikováno v: Bioorganic chemistry [Bioorg Chem] 2023 Sep; Vol. 138, pp. 106615. Date of Electronic Publication: 2023 May 19.

Leishmania Vesicle-Depleted Exoproteome: What, Why, and How?

Autor: Esteves S; Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal., Costa I; Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal., Luelmo S; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal., Santarém N; Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal., Cordeiro-da-Silva A; Laboratory of Microbiology, Department of Biological Sciences, Faculty of Pharmacy, University of Porto, 4050-313 Porto, Portugal.; Institute for Research and Innovation in Health (i3S), University of Porto, 4200-135 Porto, Portugal.

Publikováno v: Microorganisms [Microorganisms] 2022 Dec 08; Vol. 10 (12). Date of Electronic Publication: 2022 Dec 08.

SIOG2021-0106 - Poor surgical outcomes in frail older patients with pancreatic cancer when using VMS as frailty score

Autor: Dekker, R., Souwer, D., Berzina, A., Luelmo, S., Mieog, S., Lucassen, C., Michiels, N., Portielje, J., van den Bos, F.

Publikováno v: In Journal of Geriatric Oncology December 2021 12(8) Supplement 1:S55-S56