Low dose isoflurane exerts opposing effects on neuronal network excitability in neocortex and hippocampus.

Autor: Klaus Becker, Matthias Eder, Andreas Ranft, Ludwig von Meyer, Walter Zieglgänsberger, Eberhard Kochs, Hans-Ulrich Dodt

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e39346 (2012)

The anesthetic excitement phase occurring during induction of anesthesia with volatile anesthetics is a well-known phenomenon in clinical practice. However, the physiological mechanisms underlying anesthetic-induced excitation are still unclear. Here

Externí odkaz: https://doaj.org/article/8328dad00ca04a5685b9d1cb14a49ef9

Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation

Autor: Matthias Eder, Rainer Haseneder, Ludwig von Meyer, Stephan Kratzer, Eberhard Kochs, Gerhard Rammes

Publikováno v: European Journal of Pharmacology. 623:47-51

Isoflurane and sevoflurane are commonly used volatile anaesthetics. Although acting via similar cellular mechanisms, the effect of different volatile anaesthetics on synaptic plasticity might differ. In the present study, using acute murine brain sli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c910f4086b494a0e5709cb7da3daec2b
https://doi.org/10.1016/j.ejphar.2009.09.022

Drug death autopsies at the Munich Institute of Forensic Medicine (1981–1992)

Autor: Randolph Penning, Gustav Drasch, Emmerich Fromm, Peter Betz, Ludwig von Meyer, G. Kauert

Publikováno v: Forensic Science International. 62:135-139

A total of 638 drug death autopsy cases in southern Bavaria from 1981 to 1992 were analysed, including epidemiological and toxicological investigations. The rate of HIV infections decreased during the last few years. Cocaine does not (yet) play a maj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0401809b094d33a8e7925d4403f1d9
https://doi.org/10.1016/0379-0738(93)90058-i

4-Hydroxy-1-(3-pyridyl)-1-butanone-releasing DNA adducts in lung, lower esophagus and cardia of sudden death victims

Autor: Anthony R. Tricker, Daniel Hölzle, Elmar Richter, Ludwig von Meyer, Daniela Schlöbe, Dorothea Hatz

Publikováno v: Toxicology. 245(1-2)

4-Hydroxy-l-(3-pyridyl)-l-butanone (HPB)-releasing adducts are formed by metabolic activation of N'-nitrosonornicotine and 4-(methylnitrosamino)-l-(3-pyridyl)-l-butanone and have been proposed as specific biomarkers for exposure to tobacco smoke. How

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b621fa858647b5db504c8d1fbf675da
https://pubmed.ncbi.nlm.nih.gov/18243467

Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial

Autor: K. Jeganathan, Shaluka Jayamanne, Shifa Azher, Mohamed Hussain Rezvi Sheriff, Andrew H. Dawson, Franz Worek, Michael Eddleston, Edmund Juszczak, Nicola Alder, Lalith Senarathna, Ludwig von Meyer, Peter Eyer, Fahim Mohamed, Ariyasena Hittarage, Nicholas A. Buckley

Publikováno v: Eddleston, M, Eyer, P, Worek, F, Juszczak, E, Alder, N, Mohamed, F, Senarathna, L, Hittarage, A, Azher, S, Jeganathan, K, Jayamanne, S, von Meyer, L, Dawson, A H, Sheriff, M H R & Buckley, N A 2009, ' Pralidoxime in Acute Organophosphorus Insecticide Poisoning—A Randomised Controlled Trial ', PLoS Medicine, vol. 6, no. 6, e1000104 . https://doi.org/10.1371/journal.pmed.1000104
PLoS Medicine, Vol 6, Iss 6, p e1000104 (2009)
PLoS Medicine

In a randomized controlled trial of individuals who had taken organophosphorus insecticides, Michael Eddleston and colleagues find that there is no evidence that the addition of the antidote pralidoxime offers benefit over atropine and supportive car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::942a0456d2b0b7fae2df1f5de311ceb6
https://doi.org/10.1371/journal.pmed.1000104