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pro vyhledávání: '"Ludwig William Stuart"'
Autor:
Daniel D. Sternbach, Timothy M. Willson, Peter Brown, Kevin G. Liu, William R. Oliver, Kelli D. Plunket, Ludwig William Stuart, Millard H. Lambert, Ronda J. Ott, Lisa M. Leesnitzer
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:2959-2962
We have developed a general solid-phase synthesis for identification of PPAR ligands. Synthesis of a 480-member library led to the identification of a potent PPAR gamma/delta dual agonist 23. Compound 23 showed good plasma exposure in rats and demons
Autor:
Daniel D. Sternbach, Peter Brown, Ronda J. Ott, Ludwig William Stuart, Millard H. Lambert, Kevin G. Liu, Kelli D. Plunket, Timothy M. Willson, Lisa M. Leesnitzer, William R. Oliver
Publikováno v:
ChemInform. 33
We have developed a general solid-phase synthesis for identification of PPAR ligands. Synthesis of a 480-member library led to the identification of a potent PPAR gamma/delta dual agonist 23. Compound 23 showed good plasma exposure in rats and demons