Zobrazeno 1 - 10
of 445
pro vyhledávání: '"Ludwig Kiesel"'
Autor:
Lidia A. Mielke Cabello, Gabriela Meresman, Dogus Darici, Noelia Carnovale, Birthe Heitkötter, Miriam Schulte, Nancy A. Espinoza-Sánchez, Quang-Khoi Le, Ludwig Kiesel, Sebastian D. Schäfer, Martin Götte
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 876 (2024)
Ferroptosis, an iron-dependent form of non-apoptotic cell death, plays a pivotal role in various diseases and is gaining considerable attention in the realm of endometriosis. Considering the classical pathomechanism theories, we hypothesized that fer
Externí odkaz:
https://doaj.org/article/304106cd3d0c40af8069a27a2180ef60
Autor:
Herjan J. T. Coelingh Bennink, Iman J. Schultz, Marcus Schmidt, V. Craig Jordan, Paula Briggs, Jan F. M. Egberts, Kristina Gemzell-Danielsson, Ludwig Kiesel, Kirsten Kluivers, Jan Krijgh, Tommaso Simoncini, Frank Z. Stanczyk, Robert D. Langer
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Many factors, including reproductive hormones, have been linked to a woman’s risk of developing breast cancer (BC). We reviewed the literature regarding the relationship between ovulatory menstrual cycles (MCs) and BC risk. Physiological v
Externí odkaz:
https://doaj.org/article/29597ca8e60744538de2e4f76d9a93a7
Autor:
Marina Sourouni, Carl Opitz, Isabel Radke, Ludwig Kiesel, Joke Tio, Martin Götte, Marie‐Kristin vonWahlde
Publikováno v:
Cancer Reports, Vol 6, Iss 4, Pp n/a-n/a (2023)
Abstract Background Ductal carcinoma in situ (DCIS) is a precursor form of breast cancer. 13%–50% of these lesions will progress to invasive breast cancer, but the individual progression risk cannot be estimated. Therefore, all patients receive the
Externí odkaz:
https://doaj.org/article/3706ad351d6347d68eb0123ab93790b7
Autor:
Anna Stejskalová, Victoria Fincke, Melissa Nowak, Yvonne Schmidt, Katrin Borrmann, Marie-Kristin von Wahlde, Sebastian D. Schäfer, Ludwig Kiesel, Burkhard Greve, Martin Götte
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Endometriosis is a painful gynecological condition characterized by ectopic growth of endometrial cells. Little is known about its pathogenesis, which is partially due to a lack of suitable experimental models. Here, we use endometrial strom
Externí odkaz:
https://doaj.org/article/b8b9f85f6a7e4d00ad06a95a5e0ba396
Autor:
Katharina Hilgers, Sherif Abdelaziz Ibrahim, Ludwig Kiesel, Burkhard Greve, Nancy A. Espinoza-Sánchez, Martin Götte
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Cervical cancer ranks fourth among the most commonly diagnosed malignant tumors in women worldwide. Previously published evidence suggested a possible connection between the expression of the membrane-bound heparan sulfate proteoglycan syndecan-1 (Sd
Externí odkaz:
https://doaj.org/article/cbdefcfffefd4cb28376f9430306a921
Autor:
Felipe C. O. B. Teixeira, Archana Vijaya Kumar, Sampath Kumar Katakam, Cinzia Cocola, Paride Pelucchi, Monika Graf, Ludwig Kiesel, Rolland Reinbold, Mauro S. G. Pavão, Burkhard Greve, Martin Götte
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Heparan sulfate (HS) is a glycosaminoglycan found mainly in its protein-conjugated form at the cell surface and the extracellular matrix. Its high sulfation degree mediates functional interactions with positively charged amino acids in proteins. 2-O
Externí odkaz:
https://doaj.org/article/670d6cb63448476f98ff5f095c288aa4
Publikováno v:
Biomedicines, Vol 8, Iss 8, p 291 (2020)
Downregulated microRNA-142-3p signaling contributes to the pathogenesis of endometriosis, an invasive disease where the lining of the uterus grows at ectopic locations, by yet incompletely understood mechanisms. Using bioinformatics and in vitro assa
Externí odkaz:
https://doaj.org/article/dfbf247162b248b19cf3fcfb909bde32
miR-142-3p attenuates breast cancer stem cell characteristics and decreases radioresistance in vitro
Autor:
Fabian M Troschel, Nicolas Böhly, Katrin Borrmann, Timo Braun, Alexander Schwickert, Ludwig Kiesel, Hans Theodor Eich, Martin Götte, Burkhard Greve
Publikováno v:
Tumor Biology, Vol 40 (2018)
Effectively targeting cancer stem cells, a subpopulation of tumorigenic, aggressive, and radioresistant cells, holds therapeutic promise. However, the effects of the microRNA miR-142-3p, a small endogenous regulator of gene expression on breast cance
Externí odkaz:
https://doaj.org/article/7c80a551a3ac447186d134a9a1e07817
Autor:
Alexander Schwickert, Esther Weghake, Kathrin Brüggemann, Annika Engbers, Benjamin F Brinkmann, Björn Kemper, Jochen Seggewiß, Christian Stock, Klaus Ebnet, Ludwig Kiesel, Christoph Riethmüller, Martin Götte
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143993 (2015)
MicroRNAs (miRNAs, micro ribonucleic acids) are pivotal post-transcriptional regulators of gene expression. These endogenous small non-coding RNAs play significant roles in tumorigenesis and tumor progression. miR-142-3p expression is dysregulated in
Externí odkaz:
https://doaj.org/article/80b110fb41814150b0849a143158fdcf
Autor:
Sherif A Ibrahim, Hebatallah Hassan, Laura Vilardo, Sampath Katakam Kumar, Archana Vijaya Kumar, Reinhard Kelsch, Cornelia Schneider, Ludwig Kiesel, Hans Theodor Eich, Ileana Zucchi, Rolland Reinbold, Burkhard Greve, Martin Götte
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e85737 (2013)
Syndecan-1 (CD138), a heparan sulfate proteoglycan, acts as a coreceptor for growth factors and chemokines and is a molecular marker associated with epithelial-mesenchymal transition during development and carcinogenesis. Resistance of Syndecan-1-def
Externí odkaz:
https://doaj.org/article/ef13eddcc1354f3a82b2960d886f9512