Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Ludwig KA"'
Publikováno v:
Clinical and Experimental Gastroenterology, Vol 2015, Iss default, Pp 231-235 (2015)
Nicholas G Berger, Timothy J Ridolfi, Kirk A LudwigDivision of Colorectal Surgery, Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin USAAbstract: Postoperative Ileus (POI), which occurs after surgical manipulation of the bowel
Externí odkaz:
https://doaj.org/article/2045ed76a6224259800adff05211224d
Autor:
Perrine Janiaud, Chiara Zecca, Anke Salmen, Pascal Benkert, Sabine Schädelin, Annette Orleth, Lilian Demuth, Aleksandra Maleska Maceski, Cristina Granziera, Johanna Oechtering, David Leppert, Tobias Derfuss, Lutz Achtnichts, Oliver Findling, Patrick Roth, Patrice Lalive, Marjolaine Uginet, Stefanie Müller, Caroline Pot, Robert Hoepner, Giulio Disanto, Claudio Gobbi, Leila Rooshenas, Matthias Schwenkglenks, Mark J. Lambiris, Ludwig Kappos, Jens Kuhle, Özgür Yaldizli, Lars G. Hemkens
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Treatment decisions for persons with relapsing–remitting multiple sclerosis (RRMS) rely on clinical and radiological disease activity, the benefit-harm profile of drug therapy, and preferences of patients and physicians. However
Externí odkaz:
https://doaj.org/article/2dbdfb286bde4ad5a8fa355b8dcd0b9d
Autor:
Tobias Derfuss, Robert Bermel, Chien-Ju Lin, Stephen L. Hauser, Ludwig Kappos, Timothy Vollmer, Giancarlo Comi, Gavin Giovannoni, Hans-Peter Hartung, Martin S. Weber, Jianmei Wang, Nikki Jessop, Cathy Chognot, Licinio Craveiro, Amit Bar-Or
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: Patients with multiple sclerosis (PwMS) have an increased risk of infections. Objectives: To characterize incidence, clinical characteristics, outcomes and risk factors of infections, and serious infections (SIs) in ocrelizumab (OCR)-trea
Externí odkaz:
https://doaj.org/article/aed1889aa6044652a518886ae29cb31b
Autor:
Lukas Steinegger, Nathalie Nierobisch, Anthony De Vere-Tyndall, Bettina Schreiner, Patrick Roth, Ludwig Kappos, Veronika Kana, Marina Herwerth
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
ObjectivesDaratumumab, a monoclonal antibody against CD38, is increasingly used in the treatment of multiple myeloma, other hematological malignancies and autoimmune diseases. Little is known about its CNS toxicity. We present a case of a patient wit
Externí odkaz:
https://doaj.org/article/5dcfcdf75d2b4885a153cea12666cf40
Autor:
Muhamed Barakovic, Matthias Weigel, Alessandro Cagol, Sabine Schaedelin, Riccardo Galbusera, Po-Jui Lu, Xinjie Chen, Lester Melie-Garcia, Mario Ocampo-Pineda, Erik Bahn, Christine Stadelmann, Marco Palombo, Ludwig Kappos, Jens Kuhle, Stefano Magon, Cristina Granziera
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Pathological data showed focal inflammation and regions of diffuse neuronal loss in the cortex of people with multiple sclerosis (MS). In this work, we applied a novel model (“soma and neurite density imaging (SANDI)”) to multishell diff
Externí odkaz:
https://doaj.org/article/71285021003c4428bcde1d1650746e4e
Autor:
Jiwon Oh, Luca Capezzuto, Lito Kriara, Jens Schjodt-Eriksen, Johan van Beek, Corrado Bernasconi, Xavier Montalban, Helmut Butzkueven, Ludwig Kappos, Gavin Giovannoni, Riley Bove, Laura Julian, Mike Baker, Christian Gossens, Michael Lindemann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Floodlight Open was a global, open-access, digital-only study designed to understand the drivers and barriers in deployment and use of a smartphone app in a naturalistic setting and broad study population of people with and without multiple
Externí odkaz:
https://doaj.org/article/63fe8ec56ad740f388dff117b0187330
Autor:
Jens Kuhle, David Leppert, Giancarlo Comi, Nicola de Stefano, Ludwig Kappos, Mark S. Freedman, Andrea Seitzinger, Sanjeev Roy
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: In REFLEX, subcutaneous interferon beta-1a (sc IFN β-1a) delayed the onset of multiple sclerosis (MS) in patients with a first clinical demyelinating event (FCDE). Objectives: This post hoc analysis aimed to determine whether baseline se
Externí odkaz:
https://doaj.org/article/d8fa4f91b5374206af1b0e490b8d88a2
Autor:
Martina Greselin, Po-Jui Lu, Lester Melie-Garcia, Mario Ocampo-Pineda, Riccardo Galbusera, Alessandro Cagol, Matthias Weigel, Nina de Oliveira Siebenborn, Esther Ruberte, Pascal Benkert, Stefanie Müller, Sebastian Finkener, Jochen Vehoff, Giulio Disanto, Oliver Findling, Andrew Chan, Anke Salmen, Caroline Pot, Claire Bridel, Chiara Zecca, Tobias Derfuss, Johanna M. Lieb, Michael Diepers, Franca Wagner, Maria I. Vargas, Renaud Du Pasquier, Patrice H. Lalive, Emanuele Pravatà, Johannes Weber, Claudio Gobbi, David Leppert, Olaf Chan-Hi Kim, Philippe C. Cattin, Robert Hoepner, Patrick Roth, Ludwig Kappos, Jens Kuhle, Cristina Granziera
Publikováno v:
Bioengineering, Vol 11, Iss 8, p 858 (2024)
The detection of contrast-enhancing lesions (CELs) is fundamental for the diagnosis and monitoring of patients with multiple sclerosis (MS). This task is time-consuming and suffers from high intra- and inter-rater variability in clinical practice. Ho
Externí odkaz:
https://doaj.org/article/753b7b7b06c042a89d9dbeabe7219d4d
Autor:
Stephen L. Hauser, Ludwig Kappos, Amit Bar-Or, Heinz Wiendl, David Paling, Mitzi Williams, Ralf Gold, Andrew Chan, Ron Milo, Ayan Das Gupta, Goeril Karlsson, Roseanne Sullivan, Gordon Graham, Martin Merschhemke, Dieter A. Häring, Patrick Vermersch
Publikováno v:
Neurology and Therapy, Vol 12, Iss 5, Pp 1491-1515 (2023)
Abstract The importance of B cells in multiple sclerosis (MS) has been demonstrated through the advent of B-cell-depleting anti-CD20 antibody therapies. Ofatumumab is the first fully human anti-CD20 monoclonal antibody (mAb) developed and tested for
Externí odkaz:
https://doaj.org/article/eebd67c7598744dda6a94266f7a71dd5
Autor:
Amit Bar-Or, Gian-Andrea Thanei, Christopher Harp, Corrado Bernasconi, Ulrike Bonati, Anne H. Cross, Saloumeh Fischer, Laura Gaetano, Stephen L. Hauser, Robert Hendricks, Ludwig Kappos, Jens Kuhle, David Leppert, Fabian Model, Annette Sauter, Harold Koendgen, Xiaoming Jia, Ann E. Herman
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104662- (2023)
Summary: Background: Neurofilament light chain (NfL), a neuronal cytoskeletal protein that is released upon neuroaxonal injury, is associated with multiple sclerosis (MS) relapsing activity and has demonstrated some prognostic ability for future rela
Externí odkaz:
https://doaj.org/article/e7ff9f024a2e4966833fd5346456e54f