Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Ludwig J. Dubois"'
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Background Clostridium spp. has demonstrated therapeutic potential in cancer treatment through intravenous or intratumoral administration. This approach has expanded to include non-pathogenic clostridia for the treatment of various diseases,
Externí odkaz:
https://doaj.org/article/8642fa6a1f7340c896647a90306191d6
Autor:
Lin Chen, Montserrat Elizalde, Ludwig J. Dubois, Anjali A. Roeth, Ulf P. Neumann, Steven W. M. Olde Damink, Frank G. Schaap, Gloria Alvarez-Sola
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7279 (2024)
Cholangiocarcinoma (CCA), or bile duct cancer, is the second most common liver malignancy, with an increasing incidence in Western countries. The lack of effective treatments associated with the absence of early symptoms highlights the need to search
Externí odkaz:
https://doaj.org/article/9fe8c6e7562448c9b1dae0bfb1890b61
Autor:
Merel R. Aberle, Rianne D.W. Vaes, Wouter R.P.H. van deWorp, Ludwig J. Dubois, Natasja G. Lieuwes, Rianne Biemans, Ramon C.J. Langen, Frederik‐Jan vanSchooten, Ronald M. vanDam, Steven W.M. Olde Damink, Sander S. Rensen
Publikováno v:
JCSM Rapid Communications, Vol 6, Iss 1, Pp 4-17 (2023)
Abstract Background The poor survival of pancreatic cancer patients is largely attributable to cachexia, a syndrome of severe weight and muscle loss. To investigate the aetiology of cancer cachexia, preclinical models that closely recapitulate the hu
Externí odkaz:
https://doaj.org/article/ea6afd19bc9d420b90c5eedee2af6e42
Autor:
Marion T. J. van den Bosch, Bryony J. Telford, Sanaz Yahyanejad, Thijs de Gunst, Harm C. den Boer, Rogier M. Vos, Chantal L. Duurland, Rianne Biemans, Ludwig J. Dubois, Laurens A. H. van Pinxteren, Roel Q. J. Schaapveld, Michel Janicot
Publikováno v:
Frontiers in Drug Discovery, Vol 3 (2023)
As cancer is a multifactorial disease, the multimodal action of microRNAs makes them an attractive tool for novel therapeutic approaches. The tumor suppressive miR-7-5p has been shown to act on many aspects of oncogenesis, including cell proliferatio
Externí odkaz:
https://doaj.org/article/39e32167fc4c42c8971d2b5dfc2308e8
Autor:
Kathryn H. Brown, Mihaela Ghita, Ludwig J. Dubois, Dirk de Ruysscher, Kevin M. Prise, Frank Verhaegen, Karl T. Butterworth
Publikováno v:
Clinical and Translational Radiation Oncology, Vol 34, Iss , Pp 112-119 (2022)
Background and purpose: To provide a scoping review of published studies using small animal irradiators and highlight the progress in preclinical radiotherapy (RT) studies enabled by these platforms since their development and commercialization in 20
Externí odkaz:
https://doaj.org/article/9b553f704e0a43eca840dbfeabb33a5b
Autor:
Georgios Lappas, Nick Staut, Natasja G. Lieuwes, Rianne Biemans, Cecile J.A. Wolfs, Stefan J. van Hoof, Ludwig J. Dubois, Frank Verhaegen
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 21, Iss , Pp 11-17 (2022)
Background and purpose: In preclinical radiation studies, there is great interest in quantifying the radiation response of healthy tissues. Manual contouring has significant impact on the treatment-planning because of variation introduced by human in
Externí odkaz:
https://doaj.org/article/f628b596bdf6430399e591e1bb319500
Autor:
Rihab Hami, Sena Apeke, Pascal Redou, Laurent Gaubert, Ludwig J. Dubois, Philippe Lambin, Dimitris Visvikis, Nicolas Boussion
Publikováno v:
Journal of Imaging, Vol 9, Iss 6, p 124 (2023)
Despite the intensive use of radiotherapy in clinical practice, its effectiveness depends on several factors. Several studies showed that the tumour response to radiation differs from one patient to another. The non-uniform response of the tumour is
Externí odkaz:
https://doaj.org/article/432d5eb67ea043b1a19294fa5981dbe9
Autor:
Jianhua Cao, Benjamin Balluff, Martijn Arts, Ludwig J. Dubois, Luc J. C. van Loon, Tilman M. Hackeng, Hans M. H. van Eijk, Gert Eijkel, Lara R. Heij, Zita Soons, Steven W. M. Olde Damink, Ron M. A. Heeren
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-8 (2021)
Abstract Background Metabolic reprogramming is a common phenomenon in tumorigenesis and tumor progression. Amino acids are important mediators in cancer metabolism, and their kinetics in tumor tissue are far from being understood completely. Mass spe
Externí odkaz:
https://doaj.org/article/846943473bac457a8852013c33ac0911
Autor:
Annemarie J. F. Westheim, Lara M. Stoffels, Ludwig J. Dubois, Jeroen van Bergenhenegouwen, Ardy van Helvoort, Ramon C. J. Langen, Ronit Shiri-Sverdlov, Jan Theys
Publikováno v:
Frontiers in Nutrition, Vol 9 (2022)
Although immunotherapy represents one of the most potent therapeutic anti-cancer approaches, only a limited number of patients shows clinical benefit. Recent evidence suggests that patients' nutritional status plays a major role in immunotherapy outc
Externí odkaz:
https://doaj.org/article/8fb279e41a12453f9a10837849a5c3c5
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3763 (2023)
Radiotherapy (RT) is a key player in the treatment of head and neck cancer (HNC). The RT response, however, is variable and influenced by multiple tumoral and tumor microenvironmental factors, such as human papillomavirus (HPV) infections and hypoxia
Externí odkaz:
https://doaj.org/article/dffa93fd3dd242f1bae8796d674f1c32