Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ludvig Ekdahl"'
Autor:
Molly Went, Laura Duran-Lozano, Gisli H. Halldorsson, Andrea Gunnell, Nerea Ugidos-Damboriena, Philip Law, Ludvig Ekdahl, Amit Sud, Gudmar Thorleifsson, Malte Thodberg, Thorunn Olafsdottir, Antton Lamarca-Arrizabalaga, Caterina Cafaro, Abhishek Niroula, Ram Ajore, Aitzkoa Lopez de Lapuente Portilla, Zain Ali, Maroulio Pertesi, Hartmut Goldschmidt, Lilja Stefansdottir, Sigurdur Y. Kristinsson, Simon N. Stacey, Thorvardur J. Love, Saemundur Rognvaldsson, Roman Hajek, Pavel Vodicka, Ulrika Pettersson-Kymmer, Florentin Späth, Carolina Schinke, Frits Van Rhee, Patrick Sulem, Egil Ferkingstad, Grimur Hjorleifsson Eldjarn, Ulf-Henrik Mellqvist, Ingileif Jonsdottir, Gareth Morgan, Pieter Sonneveld, Anders Waage, Niels Weinhold, Hauke Thomsen, Asta Försti, Markus Hansson, Annette Juul-Vangsted, Unnur Thorsteinsdottir, Kari Hemminki, Martin Kaiser, Thorunn Rafnar, Kari Stefansson, Richard Houlston, Björn Nilsson
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Multiple myeloma (MM) is an incurable malignancy of plasma cells. Epidemiological studies indicate a substantial heritable component, but the underlying mechanisms remain unclear. Here, in a genome-wide association study totaling 10,906 case
Externí odkaz:
https://doaj.org/article/45458eb3feec4e09b1c186e45ec468d5
Autor:
Ram Ajore, Jenny Mattsson, Maroulio Pertesi, Ludvig Ekdahl, Zain Ali, Markus Hansson, Björn Nilsson
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/6843af994edf4cd58166e7ae292d195f
Autor:
Caterina Cafaro, Zain Ali, Antton Lamarca, Daniela Torres Di Bello, Laura Duran Lozano, Ludvig Ekdahl, Malte Thodberg, Maroulio Pertesi, Aitzkoa Lopez de Lapuente Portilla, Björn Nilsson
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/61567c8c87054f369e035b6bcf636957
Autor:
Jenny Mattsson, Ludvig Ekdahl, Fredrik Junghus, Ram Ajore, Eva Erlandsson, Abhishek Niroula, Maroulio Pertesi, Björn Frendéus, Ingrid Teige, Björn Nilsson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Efficient deconvolution of antibody targets is needed for phenotype-based discovery. Here, the authors investigate a deconvolution approach based on pooled CRISPR Cas9 to achieve 97% deconvolution success rate.
Externí odkaz:
https://doaj.org/article/6e2a5135b9de48a8b79f53b16495e80f
Autor:
Björn Nilsson, Björn Frendéus, Eva Erlandsson, Maroulio Pertesi, Ingrid Teige, Abhishek Niroula, Jenny Mattsson, Ludvig Ekdahl, Fredrik Junghus, Ram Ajore
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Nature Communications
Nature Communications
Therapeutic antibodies are transforming the treatment of cancer and autoimmune diseases. Today, a key challenge is finding antibodies against new targets. Phenotypic discovery promises to achieve this by enabling discovery of antibodies with therapeu
Autor:
Aitzkoa Lopez de Lapuente Portilla, Ludvig Ekdahl, Caterina Cafaro, Zain Ali, Natsumi Miharada, Gudmar Thorleifsson, Kristijonas Žemaitis, Antton Lamarca Arrizabalaga, Malte Thodberg, Maroulio Pertesi, Parashar Dhapola, Erik Bao, Abhishek Niroula, Divya Bali, Gudmundur Norddahl, Nerea Ugidos Damboriena, Vijay G. Sankaran, Göran Karlsson, Unnur Thorsteinsdottir, Jonas Larsson, Kari Stefansson, Björn Nilsson
Publikováno v:
Blood
Stem cell transplantation is a cornerstone in the treatment of blood malignancies. The most common method to harvest stem cells for transplantation is by leukapheresis, requiring mobilization of CD34+ hematopoietic stem and progenitor cells (HSPCs) f
Autor:
Kristijonas Zemaitis, Unnur Thorsteinsdottir, Gudmundur L. Norddahl, Björn Nilsson, Nerea Ugidos Damboriena, Aitzkoa Lopez de Lapuente Portilla, Maroulio Pertesi, Jonas Larsson, Antton Lamarca Arrizabalaga, Caterina Cafaro, Vijay G. Sankaran, Gudmar Thorleifsson, Erik L. Bao, Natsumi Miharada, Parashar Dhapola, Malte Thodberg, Zain Ali, Abhishek Niroula, Divya Bali, Ludvig Ekdahl, Kari Stefansson, Göran Karlsson
Understanding how hematopoietic stem and progenitor cells (HSPCs) are regulated is of central importance for the development of new therapies for blood disorders and stem cell transplantation. To date, HSPC regulation has been extensively studied in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03b48e7c73c7adfec34818fca32af86
https://doi.org/10.1101/2021.03.31.437808
https://doi.org/10.1101/2021.03.31.437808
Autor:
Ellinor Johnsson, Anna-Karin Wihlborg, Björn Nilsson, Maroulio Pertesi, Linnea Järvstråt, Angelica Palm, Ludvig Ekdahl
Publikováno v:
Communications Biology
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
Communications Biology, Vol 2, Iss 1, Pp 1-11 (2019)
The landscape of somatic acquired deletions in cancer cells is shaped by positive and negative selection. Recurrent deletions typically target tumor suppressor, leading to positive selection. Simultaneously, loss of a nearby essential gene can lead t