Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Ludovit Paulis"'
Autor:
Fedor Simko, Peter Stanko, Kristina Repova, Tomas Baka, Kristina Krajcirovicova, Silvia Aziriova, Oliver Domenig, Stefan Zorad, Michaela Adamcova, Ludovit Paulis
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 173, Iss , Pp 116391- (2024)
This study investigated whether sacubitril/valsartan or valsartan are able to prevent left ventricular (LV) fibrotic remodelling and dysfunction in two experimental models of pre-hypertension induced by continuous light (24 hours/day) exposure or by
Externí odkaz:
https://doaj.org/article/05d6f890c43b48249b41330a8104e901
Autor:
Tomas Jasenovec, Dominika Radosinska, Marta Kollarova, Norbert Vrbjar, Peter Balis, Simona Trubacova, Ludovit Paulis, Lubomira Tothova, Ivana Shawkatova, Jana Radosinska
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1227 (2022)
The objective of our study was to contribute to the characterization of monocrotaline-induced pulmonary arterial hypertension (PAH) in a rat model, with emphasis on the renin–angiotensin–aldosterone system, parameters of oxidative stress, the act
Externí odkaz:
https://doaj.org/article/385c659c07d54d5b9e634e136e2695ae
Autor:
Fedor Simko, Tomas Baka, Peter Stanko, Kristina Repova, Kristina Krajcirovicova, Silvia Aziriova, Oliver Domenig, Stefan Zorad, Michaela Adamcova, Ludovit Paulis
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1844 (2022)
This study investigated whether sacubitril/valsartan and ivabradine are able to prevent left ventricular (LV) fibrotic remodelling and dysfunction in a rat experimental model of spontaneous hypertension (spontaneously hypertensive rats, SHRs) and whe
Externí odkaz:
https://doaj.org/article/549c27f1c5e74ae1953caf8e741a55ac
Autor:
Peter Stanko, Tomas Baka, Kristina Repova, Silvia Aziriova, Kristina Krajcirovicova, Andrej Barta, Pavol Janega, Michaela Adamcova, Ludovit Paulis, Fedor Simko
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Hypertension-induced renal injury is characterized by structural kidney alterations and function deterioration. Therapeutics for kidney protection are limited, thus novel renoprotectives in hypertension are being continuously sought out. Ivabradine,
Externí odkaz:
https://doaj.org/article/07b218b7a0534088ab45a5aaf895770b
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 23, p 12800 (2021)
Alternative branches of the classical renin–angiotensin–aldosterone system (RAS) represent an important cascade in which angiotensin 2 (AngII) undergoes cleavage via the action of the angiotensin-converting enzyme 2 (ACE2) with subsequent product
Externí odkaz:
https://doaj.org/article/51fd36b88f8e4b84809e2f095866c248
Autor:
Juraj Madaric, Martina Valachovicova, Ludovit Paulis, Jana Pribojova, Renata Mateova, Katarina Sebekova, Luba Postulkova, Terezia Madaricova, Maria Bucova, Martin Mistrik, Ivan Vulev
Publikováno v:
Stem Cell Research & Therapy, Vol 8, Iss 1, Pp 1-7 (2017)
Abstract Background Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, acts as an inhibitor of angiogenesis and is associated with an increased risk of cardiovascular mortality. Administration of stem cells may affe
Externí odkaz:
https://doaj.org/article/8f41f8f749b3438aa73cf3bf74517b9b
Autor:
Michal Cagalinec, Alexandra Zahradníková, Dominika Kováčová, Ludovit Paulis, Simona Kureková, Matej Hot’ka, Jana Pavelková, Mario Plaas, Marta Novotová, Ivan Zahradník
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Wolframin (Wfs1) is a membrane protein of the sarco/endoplasmic reticulum. Wfs1 mutations are responsible for the Wolfram syndrome, characterized by diabetic and neurological symptoms. Although Wfs1 is expressed in cardiac muscle, its role in this ti
Externí odkaz:
https://doaj.org/article/45199483757148e68b928411f9acc7f1
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 6, p 3217 (2021)
The renin–angiotensin–aldosterone system (RAAS) ranks among the most challenging puzzles in cardiovascular medicine [...]
Externí odkaz:
https://doaj.org/article/e4bd69ba37df445bb2e302ef2226b235
Autor:
Barbara Szeiffova Bacova, Jana Radosinska, Gerd Wallukat, Miroslav Barancik, Anne Wallukat, Vladimir Knezl, Matus Sykora, Ludovit Paulis, Narcis Tribulova
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 526 (2020)
The arrhythmogenic potential of β1-adrenoceptor autoantibodies (β1-AA), as well as antiarrhythmic properties of omega-3 in heart diseases, have been reported while underlying mechanisms are poorly understood. We aimed to test our hypothesis that om
Externí odkaz:
https://doaj.org/article/87a719a1a86743d8b538c156083907b0
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 10, Pp 17920-17937 (2014)
The pineal hormone, melatonin (N-acetyl-5-methoxytryptamine), shows potent receptor-dependent and -independent actions, which participate in blood pressure regulation. The antihypertensive effect of melatonin was demonstrated in experimental and clin
Externí odkaz:
https://doaj.org/article/37f88b65c7a84e6090448b17ea0b2426