Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ludovica Piconi"'
Publikováno v:
Diabetes/Metabolism Research and Reviews. 24:301-309
Background Patients with long-term exposure to high levels of hyperglycaemia remain more susceptible to diabetes-related complications, even with subsequent lower levels of hyperglycaemia. We sought to confirm the hypothesis that exposure to continuo
Publikováno v:
Current Nutrition & Food Science. 3:194-199
In diabetes oxidative stress plays a key role in the pathogenesis of vascular complications, and an early step of such damage is considered the development of an endothelial dysfunction. Hyperglycemia directly promotes an endothelial dysfunction indu
Publikováno v:
Diabetes Care. 30:1694-1698
OBJECTIVE— Long-lasting hyperglycemia in type 1 diabetic patients induces permanent alterations of endothelial function by increased oxidative stress, even when glycemia is normalized. RESEARCH DESIGN AND METHODS— In this study, 36 type 1 diabeti
Autor:
Jessica E. Thorpe, Ludovica Piconi, Linda A. Warnke, K. Ross, Antonio Ceriello, Michael A. Ihnat, Csaba Szabó, Chandrashekhar D. Kamat, A. Cselenyák, R. C. Kaltreider, Z. Lacza, S. Shakir, Dixy E. Green
Publikováno v:
Diabetologia. 50:1523-1531
A long-term 'memory' of hyperglycaemic stress, even when glycaemia is normalised, has been previously reported in endothelial cells. In this report we sought to duplicate and extend this finding.HUVECs and ARPE-19 retinal cells were incubated in 5 or
Autor:
Antonio Ceriello, Dixy E. Green, Amanda C. Shanner, Ludovica Piconi, Linda A. Warnke, Ronald C. Kaltreider, Melissa Leeper, Chandrashekhar D. Kamat, Michael A. Ihnat, Jessica E. Thorpe
Publikováno v:
American Journal of Biochemistry and Biotechnology. 3:16-23
High glucose, particularly in oscillating conditions, produces an increase in oxidative stress and has been shown to result in an increase in diabetic complications, retinopathy in particular. The hypothesis of this work was that chronic exposure to
Autor:
Antonio Ceriello, Gianni Zuodar, Ludovica Piconi, Roberto Da Ros, Roberta Assaloni, Lisa Quagliaro, Amabile Maier
Publikováno v:
Atherosclerosis. 183:259-267
In this study the effects of stable and intermittent high glucose concentrations on ICAM-1, VCAM-1 and E-selectin production, PKC activity and PKCbetaI, betaII and delta isoforms expression in cultured HUVEC have been examined. In stable high glucose
Autor:
Enrico Motz, Antonio Ceriello, R. Da Ros, Amabile Maier, Lisa Quagliaro, Roberta Assaloni, Gianni Zuodar, Ludovica Piconi
Publikováno v:
Diabetologia. 48:1919-1924
Evidence suggests that postprandial hyperglycaemia may be a cardiovascular risk factor in diabetes. Oxidative stress and inflammation are involved in the pathogenesis of diabetic complications and previous studies have shown increased oxidative stres
Autor:
Lisa Quagliaro, Amabile Maier, Ludovica Piconi, Antoniom Ceriello, Roberto Da Ros, Dario Giugliano, Katherine Esposito, Roberta Assaloni
Publikováno v:
Diabetes. 53:701-710
Adhesion molecules, particularly intracellular adhesion molecule (ICAM)-1, vascular cell adhesion molecule (VCAM)-1, and E-selectin, have been associated with cardiovascular disease. Elevated levels of these molecules have been reported in diabetic p
Autor:
Antonio Ceriello, Lisa Quagliaro, G. Marra, Lucia Martinelli, R. Da Ros, Enrico Motz, Alessandro Cavarape, Roberta Assaloni, Ludovica Piconi
Publikováno v:
Diabetic Medicine. 21:171-175
Objective Recently, much attention has been focused on the possibility that the post-prandial state may be a cardiovascular risk factor in diabetes. The aim of the present study was to evaluate whether the post-prandial state is associated with endot
Autor:
Antonio Ceriello, Lucia Martinelli, Ludovica Piconi, Enrico Motz, Roberta Assaloni, Lisa Quagliaro
Publikováno v:
Diabetes. 52:2795-2804
The effects of intermittent and constant high glucose in the formation of nitrotyrosine and 8-hydroxydeoxyguanosine (markers of oxidative stress), as well as the possible linkage between oxidative stress and apoptosis in endothelial cells, have been