Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ludovica Montanucci"'
Autor:
Greta Mucignat, Ludovica Montanucci, Ramy Elgendy, Mery Giantin, Paola Laganga, Marianna Pauletto, Franco Mutinelli, Marta Vascellari, Vito Ferdinando Leone, Mauro Dacasto, Anna Granato
Publikováno v:
Genes, Vol 15, Iss 8, p 1065 (2024)
Oral melanoma (OM) is the most common malignant oral tumour among dogs and shares similarities with human mucosal melanoma (HMM), validating the role of canine species as an immunocompetent model for cancer research. In both humans and dogs, the prog
Externí odkaz:
https://doaj.org/article/6d2d2b6bd6b94b3eab940e623e07443b
Autor:
Ludovica Montanucci, David Lewis-Smith, Ryan L. Collins, Lisa-Marie Niestroj, Shridhar Parthasarathy, Julie Xian, Shiva Ganesan, Marie Macnee, Tobias Brünger, Rhys H. Thomas, Michael Talkowski, Epi25 Collaborative, Ingo Helbig, Costin Leu, Dennis Lal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Copy number variants (CNV) are established risk factors for neurodevelopmental disorders with seizures or epilepsy. With the hypothesis that seizure disorders share genetic risk factors, we pooled CNV data from 10,590 individuals with seizur
Externí odkaz:
https://doaj.org/article/5f673f8d63e1481fb289b59e8453a1ee
Autor:
Emily Huth, Ludovica Montanucci, Tobias Bruenger, Costin Leu, Gary Taylor, Emile Moura Coelho da Silva, Oscar Mancera, Omolara Kolawole, Matthew Wright, Samden Lhatoo, Gretchen Von Allmen, Dennis Lal
Publikováno v:
Genetics in Medicine Open, Vol 2, Iss , Pp 101248- (2024)
Externí odkaz:
https://doaj.org/article/417917ed69474f8ea5e6328d89d346ec
Autor:
Marianna Pauletto, Mery Giantin, Roberta Tolosi, Irene Bassan, Anisa Bardhi, Andrea Barbarossa, Ludovica Montanucci, Anna Zaghini, Mauro Dacasto
Publikováno v:
Toxins, Vol 15, Iss 9, p 555 (2023)
Aflatoxin B1 (AFB1) induces lipid peroxidation and mortality in bovine foetal hepatocyte-derived cells (BFH12), with underlying transcriptional perturbations associated mainly with cancer, cellular damage, inflammation, bioactivation, and detoxificat
Externí odkaz:
https://doaj.org/article/a4d23327d8b3483fa056ce6389ff897a
Autor:
Edoardo Pietropoli, Marianna Pauletto, Roberta Tolosi, Silvia Iori, Rosa Maria Lopparelli, Ludovica Montanucci, Mery Giantin, Mauro Dacasto, Marco De Liguoro
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9396 (2023)
Among veterinary antibiotics, flumequine (FLU) is still widely used in aquaculture due to its efficacy and cost-effectiveness. Although it was synthesized more than 50 years ago, a complete toxicological framework of possible side effects on non-targ
Externí odkaz:
https://doaj.org/article/a7973db629134539818f54345fdb7f21
Autor:
Tiziana Sanavia, Giovanni Birolo, Ludovica Montanucci, Paola Turina, Emidio Capriotti, Piero Fariselli
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 1968-1979 (2020)
Protein stability predictions are becoming essential in medicine to develop novel immunotherapeutic agents and for drug discovery. Despite the large number of computational approaches for predicting the protein stability upon mutation, there are stil
Externí odkaz:
https://doaj.org/article/4da72bc6299646fcbd3407b6a7edd179
Autor:
Luca Bargelloni, Oronzo Tassiello, Massimiliano Babbucci, Serena Ferraresso, Rafaella Franch, Ludovica Montanucci, Paolo Carnier
Publikováno v:
Aquaculture Reports, Vol 20, Iss , Pp 100661- (2021)
Disease resistance represents a key trait for breeding programs in aquaculture species. Here we re-analysed 2bRAD sequence data from two experimental challenges of gilthead sea bream with Photobacterium damsealae piscicida. Using a high quality refer
Externí odkaz:
https://doaj.org/article/0dcef7e621054e43bb7a6b8d3cac2593
Publikováno v:
Biology Direct, Vol 14, Iss 1, Pp 1-14 (2019)
Abstract Background Determining the factors involved in the likelihood of a gene being under adaptive selection is still a challenging goal in Evolutionary Biology. Here, we perform an evolutionary analysis of the human metabolic genes to explore the
Externí odkaz:
https://doaj.org/article/0b6dcfd5c8e742efb1c7d84085e63499
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S14, Pp 1-10 (2019)
Abstract Background Predicting the effect of single point variations on protein stability constitutes a crucial step toward understanding the relationship between protein structure and function. To this end, several methods have been developed to pre
Externí odkaz:
https://doaj.org/article/034989d72abe4bc9a9797911b04d7791
Autor:
Ludovica Montanucci, Hafid Laayouni, Begoña Dobon, Kevin L Keys, Jaume Bertranpetit, Juli Peretó
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208782 (2018)
Metabolic networks comprise thousands of enzymatic reactions functioning in a controlled manner and have been shaped by natural selection. Thanks to the genome data, the footprints of adaptive (positive) selection are detectable, and the strength of
Externí odkaz:
https://doaj.org/article/72aa11f27ee54eff9723eee8fcdb0337