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Akademický článek

Macrophage cytokine responses to commensal Gram-positive Lactobacillus salivarius strains are TLR2-independent and Myd88-dependent

Autor: Sreeram Udayan, Ludovica F. Buttó, Valerio Rossini, Janaki Velmurugan, Maria Martinez-Lopez, David Sancho, Silvia Melgar, Paul W. O’Toole, Ken Nally

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)

Abstract The mechanisms through which cells of the host innate immune system distinguish commensal bacteria from pathogens are currently unclear. Toll-like receptors (TLRs) are a class of pattern recognition receptors (PRRs) expressed by host cells w

Externí odkaz: https://doaj.org/article/33a9a9dedae24ab39a40cf5078e3c771

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Akademický článek

Prebiotic supplementation in frail older people affects specific gut microbiota taxa but not global diversity

Autor: Tam T. T. Tran, Fabien J. Cousin, Denise B. Lynch, Ravi Menon, Jennifer Brulc, Jillian R.-M. Brown, Eileen O’Herlihy, Ludovica F. Butto, Katie Power, Ian B. Jeffery, Eibhlís M. O’Connor, Paul W. O’Toole

Publikováno v: Microbiome, Vol 7, Iss 1, Pp 1-17 (2019)

Abstract Background There are complex interactions between aging, frailty, diet, and the gut microbiota; modulation of the gut microbiota by diet could lead to healthier aging. The purpose of this study was to test the effect of diets differing in su

Externí odkaz: https://doaj.org/article/22961fb900a94b85bf4f1a235784d880

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Akademický článek

Death Receptor 3 Signaling Controls the Balance between Regulatory and Effector Lymphocytes in SAMP1/YitFc Mice with Crohn’s Disease-Like Ileitis

Autor: Zhaodong Li, Ludovica F. Buttó, Kristine-Anne Buela, Li-Guo Jia, Minh Lam, John D. Ward, Theresa T. Pizarro, Fabio Cominelli

Publikováno v: Frontiers in Immunology, Vol 9 (2018)

Death receptor 3 (DR3), a member of the tumor necrosis factor receptor (TNFR) superfamily, has been implicated in regulating T-helper type-1 (TH1), type-2 (TH2), and type-17 (TH17) responses as well as regulatory T cell (Treg) and innate lymphoid cel

Externí odkaz: https://doaj.org/article/06e9c366db2a4626a3872986f58ee33f

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Akademický článek

MECHANISMS OF MICROBE-HOST-INTERACTION IN CROHN'S DISEASE: DYSBIOSIS VS. PATHOBIONT SELECTION

Autor: Ludovica F. Buttó, Monika eSchaubeck, Dirk eHaller

Publikováno v: Frontiers in Immunology, Vol 6 (2015)

Crohn’s disease (CD) is a systemic chronic inflammatory condition mainly characterized by discontinuous transmural pathology of the gastrointestinal tract and frequent extra-intestinal manifestations with intermittent episodes of remission and rela

Externí odkaz: https://doaj.org/article/69d8edd8451a4b4e9cf8c4a9a8369bcf

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Akademický článek

Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response.

Autor: Devon W Kavanaugh, John O'Callaghan, Ludovica F Buttó, Helen Slattery, Jonathan Lane, Marguerite Clyne, Marian Kane, Lokesh Joshi, Rita M Hickey

Publikováno v: PLoS ONE, Vol 8, Iss 6, p e67224 (2013)

In this study, we tested the hypothesis that milk oligosaccharides may contribute not only to selective growth of bifidobacteria, but also to their specific adhesive ability. Human milk oligosaccharides (3'sialyllactose and 6'sialyllactose) and a com

Externí odkaz: https://doaj.org/article/4e1e930560c64600a27a6318c6aaabae

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