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pro vyhledávání: '"Ludovic Wesolowski"'
Autor:
Ludovic Wesolowski, Jianfeng Ge, Leticia Castillon, Debora Sesia, Anna Dyas, Shoko Hirosue, Veronica Caraffini, Anne Y. Warren, Paulo Rodrigues, Giovanni Ciriello, Saroor A. Patel, Sakari Vanharanta
Publikováno v:
iScience, Vol 26, Iss 8, Pp 107360- (2023)
Summary: Lineage switching can induce therapy resistance in cancer. Yet, how lineage fidelity is maintained and how it can be lost remain poorly understood. Here, we have used CRISPR-Cas9-based genetic screening to demonstrate that loss of SMARCB1, a
Externí odkaz:
https://doaj.org/article/629e571c05cc491594e2cb0fca3f5f9e
Publikováno v:
British Journal of Cancer
Metastasis remains the leading cause of cancer-associated mortality, and a detailed understanding of the metastatic process could suggest new therapeutic avenues. However, how metastatic phenotypes arise at the genomic level has remained a major open
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d5ca9ab078f9590d7a11d47cd6f00de
https://www.repository.cam.ac.uk/handle/1810/330291
https://www.repository.cam.ac.uk/handle/1810/330291
Publikováno v:
Journal of Applied Toxicology. 38:1483-1491
Few studies have investigated non-target effects of neonicotinoid insecticides on mammalian physiology. This is largely due to the widespread perception that their weak affinity for nicotinic acetylcholine receptor subtypes in vertebrates makes mamma