Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ludovic Leriche"'
Autor:
Ludovic Leriche, Thomas B. Cooper, Anissa Abi-Dargham, Agnès Montagne, Valérie Brunner, Simon Joseph, Marlène Guiraud, Florence Gaudoux, Patrick Carberry, Mark Slifstein, Chaitanya R. Divgi, Raymond F. Suckow, Pierre Sokoloff, Ragy R. Girgis, Françoise Tonner, Shunichi Oya
Publikováno v:
Psychopharmacology. 237:519-527
F17464, a dopamine D3 receptor antagonist with relatively high D3 selectivity (70 fold vs D2 in vitro), exhibits an antipsychotic profile in preclinical studies, and therapeutic efficacy was demonstrated in a randomized placebo-controlled clinical tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f82ff674fc257a245221e943447376
https://doi.org/10.1007/s00213-019-05387-w
https://doi.org/10.1007/s00213-019-05387-w
Autor:
Cristina, Cosi, Jean-Claude, Martel, Agnès L, Auclair, Ginetta, Collo, Laura, Cavalleri, Peter, Heusler, Ludovic, Leriche, Florence, Gaudoux, Pierre, Sokoloff, Paul C, Moser, Silvia, Gatti-McArthur
Publikováno v:
European journal of pharmacology. 890
F17464 (N-(3-{4-[4-(8-Oxo-8H-[1,3]-dioxolo-[4,5-g]-chromen-7-yl)-butyl]-piperazin-1-yl}-phenyl)-methanesulfonamide, hydrochloride) is a new potential antipsychotic with a unique profile. The compound exhibits high affinity for the human dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b579498fc9f91e8cb99dd31e6d42ed6
https://pubmed.ncbi.nlm.nih.gov/33065094
https://pubmed.ncbi.nlm.nih.gov/33065094
Autor:
Ginetta Collo, Silvia Gatti-McArthur, Jean-Claude Martel, Laura Cavalleri, Peter Heusler, Florence Gaudoux, Ludovic Leriche, Pierre Sokoloff, Paul Moser, Agnès Auclair, Cristina Cosi
F17464 (N-(3-{4-[4-(8-Oxo-8H-[1,3]-dioxolo-[4,5-g]-chromen-7-yl)-butyl]-piperazin-1-yl}-phenyl)-methanesulfonamide, hydrochloride) is a new potential antipsychotic with a unique profile. The compound exhibits high affinity for the human dopamine rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e18da60ece16b164dcfcc48d13bf933
http://hdl.handle.net/11379/535724
http://hdl.handle.net/11379/535724
Autor:
Mark, Slifstein, Anissa, Abi-Dargham, Ragy R, Girgis, Raymond F, Suckow, Thomas B, Cooper, Chaitanya R, Divgi, Pierre, Sokoloff, Ludovic, Leriche, Patrick, Carberry, Shunichi, Oya, Simon K, Joseph, Marlène, Guiraud, Agnès, Montagne, Valérie, Brunner, Florence, Gaudoux, Françoise, Tonner
Publikováno v:
Psychopharmacology. 237(2)
F17464, a dopamine D3 receptor antagonist with relatively high D3 selectivity (70 fold vs D2 in vitro), exhibits an antipsychotic profile in preclinical studies, and therapeutic efficacy was demonstrated in a randomized placebo-controlled clinical tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::daaba2ad04576f3a57ec70c3ddd92730
https://pubmed.ncbi.nlm.nih.gov/31773210
https://pubmed.ncbi.nlm.nih.gov/31773210
Publikováno v:
Naunyn-Schmiedeberg's Archives of Pharmacology
This article, based on original data as well as on previously reported preclinical and clinical data that are reviewed, describes direct and indirect interactions of the D(3) receptor with N-methyl-D-aspartate receptor (NMDA) signaling and their func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b74c9c5837b4d89153ff51079d48708
http://europepmc.org/articles/PMC3558669
http://europepmc.org/articles/PMC3558669
Autor:
Ludovic Leriche, Pierre Sokoloff, C.E. Gross, Bernard Le Foll, Jorge Diaz, Olivier Guillin, Erwan Bezard
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 5:25-43
The role of the D(3) receptor has remained largely elusive before the development of selective research tools, such as selective radioligands, antibodies, various highly specific pharmacological agents and knock-out mice. The data collected so far wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a25b92538366d23a1aa1e19a8232dad
https://doi.org/10.2174/187152706784111551
https://doi.org/10.2174/187152706784111551
Publikováno v:
Neuropharmacology. 45:174-181
N-methyl-D-aspartate (NMDA)/glutamate receptor antagonists, like phencyclidine, generate schizophrenic-like symptoms in humans and behavioural abnormalities in animals, such as hyperactivity. We investigated the role of the dopamine D(3) receptor in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88179263c9498042843c2559c470d801
https://doi.org/10.1016/s0028-3908(03)00145-x
https://doi.org/10.1016/s0028-3908(03)00145-x
Autor:
Philippe Hantraye, Deniz Kirik, Nathalie Breysse, Tomas Björklund, Laurent Besret, Frédéric Dollé, Nicole Déglon, Ludovic Leriche, Marie-Claude Grégoire, Ronald J. Mandel, Thomas Carlsson
In vivogene transfer using viral vectors is an emerging therapy for neurodegenerative diseases with a clinical impact recently demonstrated in Parkinson's disease patients. Recombinant adeno-associated viral (rAAV) vectors, in particular, provide an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49044c2beb67841aa4ecf3a286cd08c
https://europepmc.org/articles/PMC6666088/
https://europepmc.org/articles/PMC6666088/
Publikováno v:
Psychopharmacogenetics ISBN: 9780387307930
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::815c51e55423bfbd48ac4fb6bc54a3cd
https://doi.org/10.1007/0-387-34577-2_14
https://doi.org/10.1007/0-387-34577-2_14
Publikováno v:
Psychopharmacology. 175
The dopamine D3 receptor has been shown to mediate conditioned effects of psychostimulants such as cocaine. The present work was aimed at determining whether drugs acting at D3 receptors alter acquisition of conditioned effects of opiates. We have us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57743b29249d9d8c9d84a83675b87e3f
https://doi.org/10.1007/s00213-004-1807-9
https://doi.org/10.1007/s00213-004-1807-9