Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ludovic Carlier"'
Autor:
Claire Lacombe, Estefania Aleman-Navaro, Thierry Drujon, Veronica Martinez-Osorio, Emmanuelle Sachon, Erika Melchy-Pérez, Ludovic Carlier, Lorena Elizabeth Fajardo Brigido, Yannick Fleury, Christophe Piesse, Guadalupe Gutiérrez-Escobedo, Alejandro De las Peñas, Irene Castaño, Florie Desriac, Jose Luis Beristain-Hernandez, Christophe Combadiere, Yvonne Rosenstein, Constance Auvynet
Publikováno v:
International Journal of Inflammation, Vol 2024 (2024)
Inflammatory and antimicrobial diseases constitute a major burden for society, and fighting them is a WHO strategic priority. Most of the treatments available to fight inflammatory diseases are anti-inflammatory drugs, such as corticosteroids or immu
Externí odkaz:
https://doaj.org/article/8d3adf6a2c4a4aba94f202f523bb8b04
Autor:
Sébastien Cardon, Yadira P. Hervis, Gérard Bolbach, Chrystel Lopin-Bon, Jean-Claude Jacquinet, Françoise Illien, Astrid Walrant, Delphine Ravault, Bingwei He, Laura Molina, Fabienne Burlina, Olivier Lequin, Alain Joliot, Ludovic Carlier, Sandrine Sagan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Engrailed2 (En2) is a transcription factor that transfers from cell to cell through unconventional pathways. The poorly understood internalization mechanism of this cationic protein is proposed to require an initial interaction with cell-sur
Externí odkaz:
https://doaj.org/article/c684e2cdb0ba43a69d9c0fdf51449845
Autor:
Sébastien Cardon, Emmanuelle Sachon, Ludovic Carlier, Thierry Drujon, Astrid Walrant, Estefanía Alemán-Navarro, Verónica Martínez-Osorio, Dominique Guianvarc'h, Sandrine Sagan, Yannick Fleury, Rodrigue Marquant, Christophe Piesse, Yvonne Rosenstein, Constance Auvynet, Claire Lacombe
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205727 (2018)
The occurrence of nosocomial infections has been on the rise for the past twenty years. Notably, infections caused by the Gram-positive bacteria Staphylococcus aureus represent a major clinical problem, as an increase in antibiotic multi-resistant st
Externí odkaz:
https://doaj.org/article/78b544e90a0947459e588490d3adcb67
SummaryTranslationally Controlled Tumour Protein (TCTP) is a pro-survival factor in tumor cells. TCTP inhibits the mitochondrial apoptosis pathway by potentiating the anti-apoptotic Bcl-2 family members Mcl-1 and Bcl-xL. Specifically, TCTP binds Bcl-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2cbb60ce7d4b6a9e01d20571a0aa3546
https://doi.org/10.1101/2022.11.05.515280
https://doi.org/10.1101/2022.11.05.515280
Publikováno v:
Journal of Biological Chemistry. :104830
Autor:
Leïla Bechtella, Edward Chalouhi, Paula Milán Rodríguez, Marine Cosset, Delphine Ravault, Françoise Illien, Sandrine Sagan, Ludovic Carlier, Olivier Lequin, Patrick F. J. Fuchs, Emmanuelle Sachon, Astrid Walrant
Publikováno v:
ACS Chemical Biology
ACS Chemical Biology, 2022, 17 (6), pp.1427-1439. ⟨10.1021/acschembio.1c00974⟩
ACS Chemical Biology, 2022, 17 (6), pp.1427-1439. ⟨10.1021/acschembio.1c00974⟩
International audience; Cell-penetrating peptides cross cell membranes through various parallel internalization pathways. Herein, we analyze the role of the negatively charged lipid phosphatidylinositol-4,5-bisphosphate (PI(4,5)P2) in the internaliza
Autor:
Asma Bourafai-Aziez, Mohammed Benabderrahmane, Hippolyte Paysant, Louis-Bastien Weiswald, Laurent Poulain, Ludovic Carlier, Delphine Ravault, Marie Jouanne, Gaël Coadou, Hassan Oulyadi, Anne-Sophie Voisin-Chiret, Jana Sopková-de Oliveira Santos, Muriel Sebban
Publikováno v:
Drug Design, Development and Therapy
Introduction With the aim of repositioning commercially available drugs for the inhibition of the anti-apoptotic myeloid cell leukemia protein, Mcl-1, implied in various cancers, five molecules, highlighted from a published theoretical screening, wer
Autor:
Alain Joliot, Astrid Walrant, Françoise Illien, Sandrine Sagan, Olivier Lequin, Gérard Bolbach, Fabienne Burlina, Jean-Claude Jacquinet, Delphine Ravault, Laura Molina, Yadira P. Hervis, Bingwei He, Sébastien Cardon, Ludovic Carlier, Chrystel Lopin-Bon
Engrailed-2 (En2) is a transcription factor that possesses as most homeoproteins the unique and intriguing property to transfer from cell to cell through unconventional pathways. The internalization mechanism of this cationic protein is far from bein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52988369e5be299a35415f6ab50205d4
https://hal.archives-ouvertes.fr/hal-03429466
https://hal.archives-ouvertes.fr/hal-03429466
Autor:
Christophe Denoyelle, Fabien Gautier, Peggy Suzanne, Frédéric Lopez, Jade Fogha, Laurent Poulain, Anne Sophie Voisin-Chiret, Sylvain Rault, Jana Sopkova-de Oliveira Santos, Rémi Legay, Martina De Pascale, Siham Hedir, Emilie Brotin, Marcella De Giorgi, Camille Denis, Louis-Bastien Weiswald, Bogdan A. Marekha, Philippe Juin, Ludovic Carlier, Ronan Bureau, Laetitia Ligat
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2018, 159, pp.357-380. ⟨10.1016/j.ejmech.2018.10.003⟩
European Journal of Medicinal Chemistry, 2018, 159, pp.357-380. ⟨10.1016/j.ejmech.2018.10.003⟩
European Journal of Medicinal Chemistry, Elsevier, 2018, 159, pp.357-380. ⟨10.1016/j.ejmech.2018.10.003⟩
European Journal of Medicinal Chemistry, 2018, 159, pp.357-380. ⟨10.1016/j.ejmech.2018.10.003⟩
International audience; Protein-protein interactions are attractive targets because they control numerous cellular processes. In oncology, apoptosis regulating Bcl-2 family proteins are of particular interest. Apoptotic cell death is controlled via P
Autor:
Lei Bruschweiler-Li, Yina Gu, Rafael Brüschweiler, Jean-Max Tyburn, Thorsten Marquardsen, Nicolas Bolik-Coulon, Cyril Charlier, Pavel Kadeřávek, Samuel F. Cousin, Ludovic Carlier, Fabien Ferrage
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2019, ⟨10.1021/jacs.8b09107⟩
Journal of the American Chemical Society, 2019, ⟨10.1021/jacs.8b09107⟩
Journal of the American Chemical Society, American Chemical Society, 2019, ⟨10.1021/jacs.8b09107⟩
Journal of the American Chemical Society, 2019, ⟨10.1021/jacs.8b09107⟩
Motions of proteins are essential for the performance of their functions. Aliphatic protein side chains and their motions play critical roles in protein interactions: for recognition and binding of partner molecules at the surface or serving as an en