Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ludovic, Gillet"'
Autor:
Matthias Weith, Jan Großbach, Mathieu Clement‐Ziza, Ludovic Gillet, María Rodríguez‐López, Samuel Marguerat, Christopher T Workman, Paola Picotti, Jürg Bähler, Ruedi Aebersold, Andreas Beyer
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 8, Pp 1-21 (2023)
Abstract The complexity of many cellular and organismal traits results from the integration of genetic and environmental factors via molecular networks. Network structure and effect propagation are best understood at the level of functional modules,
Externí odkaz:
https://doaj.org/article/4f972d70022840c5813a7645a1b8d926
Autor:
Majd A. El‐Harasis, Joseph A. Quintana, J. Roberto Martinez‐Parachini, Gregory G. Jackson, Bibin T. Varghese, Zachary T. Yoneda, Brittany S. Murphy, Diane M. Crawford, Kelsey Tomasek, Yan Ru Su, Quinn S. Wells, Dan M. Roden, Gregory F. Michaud, Pablo Saavedra, Juan Carlos Estrada, Travis D. Richardson, Arvindh N. Kanagasundram, Sharon T. Shen, Jay A. Montgomery, Christopher R. Ellis, George H. Crossley, Magdalena Eberl, Ludovic Gillet, Andre Ziegler, M. Benjamin Shoemaker
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 6 (2024)
Background Recurrence after atrial fibrillation (AF) ablation remains common. We evaluated the association between recurrence and levels of biomarkers of cardiac remodeling, and their ability to improve recurrence prediction when added to a clinical
Externí odkaz:
https://doaj.org/article/ecdb8da2b6da41c1b21abdfd26c10dbc
Autor:
Jan Grossbach, Ludovic Gillet, Mathieu Clément‐Ziza, Corinna L Schmalohr, Olga T Schubert, Maximilian Schütter, Julia S P Mawer, Christopher A Barnes, Isabell Bludau, Matthias Weith, Peter Tessarz, Martin Graef, Ruedi Aebersold, Andreas Beyer
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 5, Pp 1-21 (2022)
Abstract Genomic variation impacts on cellular networks by affecting the abundance (e.g., protein levels) and the functional states (e.g., protein phosphorylation) of their components. Previous work has focused on the former, while in this context, t
Externí odkaz:
https://doaj.org/article/7e961a966e224fa097adf21ce5f781c0
Autor:
Stefan Gerhardy, Michaela Oborská-Oplová, Ludovic Gillet, Richard Börner, Rob van Nues, Alexander Leitner, Erich Michel, Janusz J. Petkowski, Sander Granneman, Roland K. O. Sigel, Ruedi Aebersold, Vikram Govind Panse
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Ribosome biogenesis is crucially dependent on proper rRNA folding, a process assisted by chaperones. Here the authors reveal how Puf6 promotes correct rRNA folding at low temperature, a condition where mis-paired RNA folding intermediates frequently
Externí odkaz:
https://doaj.org/article/0bae3de09764483c9083cf74b1da5f94
Autor:
Yi Zhu, Tobias Weiss, Qiushi Zhang, Rui Sun, Bo Wang, Xiao Yi, Zhicheng Wu, Huanhuan Gao, Xue Cai, Guan Ruan, Tiansheng Zhu, Chao Xu, Sai Lou, Xiaoyan Yu, Ludovic Gillet, Peter Blattmann, Karim Saba, Christian D. Fankhauser, Michael B. Schmid, Dorothea Rutishauser, Jelena Ljubicic, Ailsa Christiansen, Christine Fritz, Niels J. Rupp, Cedric Poyet, Elisabeth Rushing, Michael Weller, Patrick Roth, Eugenia Haralambieva, Silvia Hofer, Chen Chen, Wolfram Jochum, Xiaofei Gao, Xiaodong Teng, Lirong Chen, Qing Zhong, Peter J. Wild, Ruedi Aebersold, Tiannan Guo
Publikováno v:
Molecular Oncology, Vol 13, Iss 11, Pp 2305-2328 (2019)
Formalin‐fixed, paraffin‐embedded (FFPE), biobanked tissue samples offer an invaluable resource for clinical and biomarker research. Here, we developed a pressure cycling technology (PCT)‐SWATH mass spectrometry workflow to analyze FFPE tissue
Externí odkaz:
https://doaj.org/article/d5ac540ae607488999e040459d781060
Autor:
Tiannan Guo, Augustin Luna, Vinodh N. Rajapakse, Ching Chiek Koh, Zhicheng Wu, Wei Liu, Yaoting Sun, Huanhuan Gao, Michael P. Menden, Chao Xu, Laurence Calzone, Loredana Martignetti, Chiara Auwerx, Marija Buljan, Amir Banaei-Esfahani, Alessandro Ori, Murat Iskar, Ludovic Gillet, Ran Bi, Jiangnan Zhang, Huanhuan Zhang, Chenhuan Yu, Qing Zhong, Sudhir Varma, Uwe Schmitt, Peng Qiu, Qiushi Zhang, Yi Zhu, Peter J. Wild, Mathew J. Garnett, Peer Bork, Martin Beck, Kexin Liu, Julio Saez-Rodriguez, Fathi Elloumi, William C. Reinhold, Chris Sander, Yves Pommier, Ruedi Aebersold
Publikováno v:
iScience, Vol 21, Iss , Pp 664-680 (2019)
Summary: Here we describe a proteomic data resource for the NCI-60 cell lines generated by pressure cycling technology and SWATH mass spectrometry. We developed the DIA-expert software to curate and visualize the SWATH data, leading to reproducible d
Externí odkaz:
https://doaj.org/article/ccb6206f1f4f4ccf946fcd290d879f5e
Autor:
Christina Ludwig, Ludovic Gillet, George Rosenberger, Sabine Amon, Ben C Collins, Ruedi Aebersold
Publikováno v:
Molecular Systems Biology, Vol 14, Iss 8, Pp 1-23 (2018)
Abstract Many research questions in fields such as personalized medicine, drug screens or systems biology depend on obtaining consistent and quantitatively accurate proteomics data from many samples. SWATH‐MS is a specific variant of data‐indepen
Externí odkaz:
https://doaj.org/article/212c63d12c084d8d8234958f755d97d2
Publikováno v:
Algorithms for Molecular Biology, Vol 12, Iss 1, Pp 1-13 (2017)
Abstract Background Given a peptide as a string of amino acids, the masses of all its prefixes and suffixes can be found by a trivial linear scan through the amino acid masses. The inverse problem is the ideal de novo peptide sequencing problem: Give
Externí odkaz:
https://doaj.org/article/9ab009abbdfe457c87f85151af57a5d8
Autor:
Jean-Sébastien Rougier, Maria C. Essers, Ludovic Gillet, Sabrina Guichard, Stephan Sonntag, Doron Shmerling, Hugues Abriel
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
Background: In cardiac ventricular muscle cells, the presence of voltage-gated sodium channels Nav1.5 at the lateral membrane depends in part on the interaction between the dystrophin–syntrophin complex and the Nav1.5 C-terminal PDZ-domain-binding
Externí odkaz:
https://doaj.org/article/40f1bfc6769543c08b5d2a4c61a582dc
Autor:
Matthias Weith, Jan Großbach, Mathieu Clement-Ziza, Ludovic Gillet, María Rodríguez-López, Samuel Marguerat, Christopher T. Workman, Paola Picotti, Jürg Bähler, Ruedi Aebersold, Andreas Beyer
The complexity of many cellular and organismal traits results from poorly understood mechanisms integrating genetic and environmental factorsviamolecular networks. Here, we show when and how genetic perturbations lead to molecular changes that are co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dddee1c2db63303d68dca79baace755
https://doi.org/10.1101/2022.12.05.519111
https://doi.org/10.1101/2022.12.05.519111
