Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ludmila S. Peres Diaz"'
Autor:
Fernando Juan Ingallina, Jorge E. Toblli, Ludmila S. Peres Diaz, Mariano Luis Schuman, Silvia I. García, María Silvina Landa, Maia Aisicovich
Publikováno v:
Journal of cardiac failure. 27(7)
Cardiac thyrotropin-releasing hormone (TRH) is a tripeptide with still unknown functions. We demonstrated that the left ventricle (LV) TRH system is hyperactivated in spontaneously hypertensive rats and its inhibition prevented cardiac hypertrophy an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e05ac6f524cb89bc8415aed532aa69
https://pubmed.ncbi.nlm.nih.gov/33865967
https://pubmed.ncbi.nlm.nih.gov/33865967
Autor:
Maia Aisicovich, María Silvina Landa, Silvia I. García, Jorge E. Toblli, Carlos José Pirola, Ludmila S. Peres Diaz, Mariano Luis Schuman
Doxorubicin is an antineoplastic in the anthracycline class widely used for the treatment of several solid tumors and blood cancers. Cardiotoxicity is the major dose-limiting adverse effect of the drug. Chronic and accumulated doxorubicin administrat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a74f39ed16d42d088c874a5484fd3a4
https://linkinghub.elsevier.com/retrieve/pii/S0024320520310985
https://linkinghub.elsevier.com/retrieve/pii/S0024320520310985
Autor:
Ludmila S. Peres Diaz, Maria Silvina Landa, Azucena L. Alvarez, Carlos José Pirola, Jorge E. Toblli, Samuel Finkielman, Mariano Luis Schuman, Gabriel Cao, Silvia I. García
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 307:H1667-H1674
Thyrotropin-releasing hormone (TRH) hyperactivity has been observed in the left ventricle of spontaneously hypertensive rats. Its long-term inhibition suppresses the development of hypertrophy, specifically preventing fibrosis. The presence of divers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7b7c2aab80294d3ce3dfb116b764e89
https://doi.org/10.1152/ajpheart.00494.2014
https://doi.org/10.1152/ajpheart.00494.2014
Autor:
Mariano Luis Schuman, Ludmila S. Peres Diaz, Silvia I. García, Maria Silvina Landa, Maia Aisicovich
Publikováno v:
Hypertension. 68
We have demonstrated TRH hyperactivity in the hypertrophied Left ventricle (LV) of SHR. Its specific inhibition attenuates hypertrophy development in spite of the significant higher pressure observed (Schuman M, Hypertension 2011). LV-TRH over-expres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd36cb97b4ece8ca3bc49a0a4730fdbe
https://doi.org/10.1161/hyp.68.suppl_1.027
https://doi.org/10.1161/hyp.68.suppl_1.027
Autor:
Ludmila S. Peres Diaz, Mariano Luis Schuman, Leonardo Paz, Jorge E. Toblli, Gabriel Cao, Samuel Finkielman, Azucena L. Alvarez, Maria Silvina Landa, Carlos José Pirola, Silvia I. García
Publikováno v:
Hypertension. 57:103-109
Local thyrotropin-releasing hormone (TRH) may be involved in cardiac pathophysiology, but its role in left ventricular hypertrophy (LVH) is still unknown. We studied whether local TRH is involved in LVH of spontaneously hypertensive rats (SHR) by inv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dda74ff811c73639da2a085527bc56d
https://doi.org/10.1161/hypertensionaha.110.161265
https://doi.org/10.1161/hypertensionaha.110.161265
Publikováno v:
Hypertension. 66
Cardiac TRH (cTRH) is overexpressed in the hypertrophied ventricle (LV) of the SHR. Additionally in vivo siRNA-TRH treatment induced downregulation of LV-TRH preventing cardiac hypertrophy and fibrosis demonstrating that TRH is involved in hypertroph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcec2921683eaa4fbea60c3d422c96ce
https://doi.org/10.1161/hyp.66.suppl_1.p141
https://doi.org/10.1161/hyp.66.suppl_1.p141