Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ludmila N. Drutskaya"'
Autor:
Björn E. Clausen, Sergei A. Nedospasov, Dmitry J. Liepinsh, Irmgard Förster, Dmitry V. Kuprash, Takaya Murakami, Ludmila N. Drutskaya, Sergei I. Grivennikov, Alexei V. Tumanov, Andrei A. Kruglov, Boris I. Marakusha, Shakhov An, Bernhard Ryffel, Lino Tessarollo
Publikováno v:
Immunity. 22:93-104
Tumor necrosis factor (TNF, TNFalpha) is implicated in various pathophysiological processes and can be either protective, as in host defense, or deleterious, as in autoimmunity or toxic shock. To uncover the in vivo functions of TNF produced by diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3691ad1d3a3ee128c69131e78131fc08
https://doi.org/10.1016/j.immuni.2004.11.016
https://doi.org/10.1016/j.immuni.2004.11.016
Autor:
Ilya G. Lyakhov, Sergei A. Nedospasov, Anatoly V. Rubtsov, Michael W. Marino, Alexei V. Tumanov, Ludmila N. Drutskaya, Shakhov An
Publikováno v:
Journal of Leukocyte Biology. 68:151-157
Mice with combined lymphotoxin-α (LTα) and tumor necrosis factor (TNF) deficiencies show defects in the structure of peripheral lymphoid organs such as spleen, lymph nodes, and gut-associated lymphoid tissues. To identify genes associated with this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f91d6478dfcf436260951e6116e5e14e
https://doi.org/10.1189/jlb.68.1.151
https://doi.org/10.1189/jlb.68.1.151
Autor:
Koichiro Abe, Dmitry V. Kuprash, Ludmila N. Drutskaya, Daisuke Ito, Sergei I. Grivennikov, Thomas Blankenstein, Zhihai Qin, Sergei A. Nedospasov
Publikováno v:
Cancer letters. 268(1)
TNF plays diverse and contrasting roles in cancer, promoting skin carcinogenesis and metastasis, but also possessing potent antitumor effects in mice. TNF via TNFR1 axis induces NFkappaB, and may contribute to inflammation-facilitated neoplasia. On t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fb80d2d0b910adc21d126b4112447df
https://pubmed.ncbi.nlm.nih.gov/18442881
https://pubmed.ncbi.nlm.nih.gov/18442881
Autor:
Sergei I, Grivennikov, Alexei V, Tumanov, Dmitry J, Liepinsh, Andrei A, Kruglov, Boris I, Marakusha, Alexander N, Shakhov, Takaya, Murakami, Ludmila N, Drutskaya, Irmgard, Förster, Björn E, Clausen, Lino, Tessarollo, Bernhard, Ryffel, Dmitry V, Kuprash, Sergei A, Nedospasov
Publikováno v:
Immunity. 22(1)
Tumor necrosis factor (TNF, TNFalpha) is implicated in various pathophysiological processes and can be either protective, as in host defense, or deleterious, as in autoimmunity or toxic shock. To uncover the in vivo functions of TNF produced by diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5084e519cf6947cd823e83e8d42440e2
https://pubmed.ncbi.nlm.nih.gov/15664162
https://pubmed.ncbi.nlm.nih.gov/15664162
Autor:
Sergei A. Nedospasov, Koichiro Abe, Kristin L. Komschlies, Daisuke Ito, Klaus Pfeffer, Alexei V. Tumanov, Shakhov An, Dmitry V. Kuprash, Takaya Murakami, Ludmila N. Drutskaya, Felix Yarovinsky
Publikováno v:
Blood. 101(4)
TNF/LTalpha/LTbeta (tumor necrosis factor/lymphotoxin-alpha/lymphotoxin-beta) triple knockout (KO) mice show a significant reduction of dendritic cell (DC) number in the spleen, presumably due to defective recruitment and/or production. To distinguis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e860c04975e1dd1f9742917d85e54bc
https://pubmed.ncbi.nlm.nih.gov/12560241
https://pubmed.ncbi.nlm.nih.gov/12560241
Autor:
Shakhov An, Michael W. Marino, Sergei A. Nedospasov, Alexei V. Tumanov, Klaus Pfeffer, Sergei I. Grivennikov, Marat Alimzhanov, Klaus Rajewsky, Ludmila N. Drutskaya, Regina L. Turetskaya, Arthur O. Anderson, Dmitry V. Kuprash
Homologous genes and gene products often have redundant physiological functions. Members of the tumor necrosis factor (TNF) family of cytokines can signal activation, proliferation, differentiation, costimulation, inhibition, or cell death, depending
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f28e89495dc0791338affadc50de3366
https://europepmc.org/articles/PMC139867/
https://europepmc.org/articles/PMC139867/
Autor:
Alexei V. Tumanov, Ludmila N. Drutskaya, Maria A. Lagarkova, Dmitry V. Kuprash, Colin L. Stewart, Sergei A. Nedospasov, Alexander V. Chervonsky, Koichiro Abe, Shakhov An, Sergei I. Grivennikov
Publikováno v:
Immunity. 17(3)
In order to definitively ascertain the functional contribution of lymphotoxin (LT) expressed by B cells, we produced mice with the LTbeta gene deleted from B cells (B-LTbeta KO mice). In contrast to systemic LTbeta deletion, in B-LTbeta KO mice only
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f925117822f87b7a8d9d4cd0a357e8a7
https://pubmed.ncbi.nlm.nih.gov/12354378
https://pubmed.ncbi.nlm.nih.gov/12354378