Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ludmila M. Kuiava"'
Autor:
Alex Philchenkov, Koh Miura, Volodymyr Tryndyak, Romano Silvestri, M P Zavelevich, Igor P. Pogribny, Dmitry Yu. Blokhin, Ludmila M. Kuiava
Publikováno v:
Cancer Biology & Therapy. 16:1820-1829
Recently, a series of novel arylthioindole compounds, potent inhibitors of tubulin polymerization and cancer cell growth, were synthesized. In the present study the effects of 2-(1H-pyrrol-3-yl)-3-((3,4,5-trimethoxyphenyl)thio)-1H-indole (ATI5 compou
Autor:
Alex S. Kiselyov, N. B. Chernysheva, Vladimir I. Ushkarov, Marina N. Semenova, Mikhail M. Raihstat, Vasyl F. Chekhun, Alex Philchenkov, Dmitry V. Demchuk, Galina A. Stashina, S. I. Firgang, Leonid D. Konyushkin, Alexander V. Samet, Dmitry Yu. Blokhin, Victor V. Semenov, M P Zavelevich, Ludmila M. Kuiava
Publikováno v:
Bioorganicmedicinal chemistry. 22(2)
A series of 1,5-diaryl- and 4,5-diaryl-1,2,3-triazole derivatives of combretastatin A4 were synthesized and evaluated as antimitotic microtubule destabilizing agents using the sea urchin embryo model. Structure–activity relationship studies identif