Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ludmila Hradilová"'
Autor:
Soňa Krupkova, Kamil Motyka, Ludmila Hradilová, Maitia Labora, Martin Mistrik, Jiři Bartek, Jan Hlaváč, Lucie Brulíková
Publikováno v:
RSC Advances. 6:23242-23251
Several Rhodamine B derivatives based on a tri-substituted pyrimidine core were prepared using solid-phase chemistry with a combinatorial approach. These compounds were screened for their basic fluorescence properties and their ability to penetrate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c09bf57dda1d5c466a890d0041c15f1d
https://doi.org/10.1039/c5ra20183g
https://doi.org/10.1039/c5ra20183g
Autor:
Viktor Krchňák, Carlos Alfonso Barea Ripoll, Agustina La-Venia, Ludmila Hradilová, Pilar Ventosa-Andrés
Publikováno v:
Chemistry - A European Journal. 21:13112-13119
Herein, we describe the synthesis of molecular scaffolds consisting of medium-sized fused heterocycles using amino acids, which are some of the most useful building blocks used by nature as well as chemists to create structural diversity. The acyclic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef99e54c0217b7e4e2cef5507bce97e
https://doi.org/10.1002/chem.201501746
https://doi.org/10.1002/chem.201501746
Autor:
Barbora Dvořáková, Ludmila Hradilová, Adam Šimáček, Lukáš Jedinák, Pavel Hradil, Valerio Bertolasi
Publikováno v:
Tetrahedron Letters. 56:53-55
A series of 2-substituted-3-diazoquinolin-4-ones is prepared by the reaction of 2-substituted-3-amino-4-chloroquinolines with sodium nitrite in sulfuric acid. Some of the obtained products are then utilised in triazole formation, reduction and a Wolf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::603541e770ffbde1ab383856cf94265c
https://doi.org/10.1016/j.tetlet.2014.09.061
https://doi.org/10.1016/j.tetlet.2014.09.061
Publikováno v:
Journal of Heterocyclic Chemistry. 50:528-533
Propargyl anthranilate, a simple and less studied molecule with several reactive sites, is widely applicable in organic synthesis. An optimized synthesis of this compound and its derivatives and the preparation of azide derivatives are described. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93f4313df4a4f36d3531bab42419c06a
https://doi.org/10.1002/jhet.1514
https://doi.org/10.1002/jhet.1514
Publikováno v:
Tetrahedron Letters. 54:1218-1221
Macrocycles were synthesised via the cyclisation of propargyl 2-azidobenzoate using ‘click’ chemistry. An LC/MS-based method for the separation of macrocycles is described. In the present work, the influence of various catalysts and reaction cond
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa72377983f1ce54ce98913867d21e30
https://doi.org/10.1016/j.tetlet.2012.12.076
https://doi.org/10.1016/j.tetlet.2012.12.076
Publikováno v:
Carbohydrate Research. 361:1-6
Two sets of new conjugates obtained from d-mannose derivatives and o-, m-, and p-substituted benzoic acid esters interconnected through a triazole ring were synthesized by Cu(I) catalyzed azide-alkyne cycloaddition. All synthesized compounds were tes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab60fa9c716726ecf2757444d615c01d
https://doi.org/10.1016/j.carres.2012.08.001
https://doi.org/10.1016/j.carres.2012.08.001
Publikováno v:
Synlett. 23:2205-2208
A simple and efficient synthesis of 2-substituted 3-amino-4-chloroquinolines and 2,4-disubstituted 3-aminoquinolines was carried out by reacting 3-amino-2,4-dichloroquinoline with various oxygen-, sulfur- and nitrogen-containing nucleophiles.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a14377a0c324af5d22222b7aae411920
https://doi.org/10.1055/s-0032-1316733
https://doi.org/10.1055/s-0032-1316733
Publikováno v:
Synthesis. 44:1398-1404
A new procedure for the preparation of macrocycles containing 1,2,3-triazole motifs is developed. The macrocyclic precursor is constructed by repetition of a series of steps which include cycloaddition of an azide with an alkyne, alkylation of a carb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ba9543e4704a44dfcdd88bb8940d723
https://doi.org/10.1055/s-0031-1290760
https://doi.org/10.1055/s-0031-1290760
Novel molecular scaffolds comprising two to four bridged and fused heterocycles were synthesized from amino acids using seven-membered endocyclic N-acyliminium ions as key intermediates in acid-mediated tandem reactions with internal nucleophiles. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2652f66555172ecc4e87ea65084c193
http://pubs.acs.org/doi/10.1021/jo501983j
http://pubs.acs.org/doi/10.1021/jo501983j
Publikováno v:
ACS combinatorial science. 16(7)
A molecular scaffold comprising a privileged structure was designed and synthesized to serve as a peptide backbone conformational constraint. The synthesis of highly functionalized 2,3,10,10a-tetrahydrobenzo[4,5]imidazo[1,2-a]pyrazin-4(1H)-ones on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54e0cf2c4a38e9334edfbfc2d8e34d72
https://pubmed.ncbi.nlm.nih.gov/24725105
https://pubmed.ncbi.nlm.nih.gov/24725105