Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ludmila Dabrowská"'
Publikováno v:
Archives of Toxicology. 93:603-613
Ethylene oxide (EO), a genotoxic industrial chemical and sterilant, forms covalent adducts with DNA and also with nucleophilic amino acids in proteins. The adduct with N-terminal valine in globin [N-(2-hydroxyethyl)valine (HEV)] has been used in biom
Autor:
Hana Chrástecká, Igor Linhart, Radka Vajtrová, Šárka Dušková, Jaroslav Mráz, Ludmila Dabrowská, Iveta Hanzlíková
Publikováno v:
Toxicology letters. 261
The in vivo fate of globin adducts with styrene 7,8-oxide (SO), an electrophilic metabolic intermediate of styrene, was studied in male Wistar rats dosed intraperitoneally with racemic SO, 100 mg/kg b.w. Regioisomeric hydroxy(phenyl)ethyl (HPE) adduc
Autor:
Frantisek Kolar, Ludmila Dabrowská, Jaroslav Mraz, Jitka Zurmanova, Jan Neckar, Dita Kasparova, Jiri Novotny
Publikováno v:
Physiological genomics. 47(12)
It has been documented that adaptation to hypoxia increases myocardial tolerance to ischemia-reperfusion (I/R) injury depending on the regimen of adaptation. Reactive oxygen species (ROS) formed during hypoxia play an important role in the induction
Publikováno v:
Sperlingová, I; Dabrowská, L; Stránský, V; Kucera, J; Tichý, M (2006). Human urine certified reference material CZ 6010: creatinine and toluene metabolites (hippuric acid and o-cresol) and a benzene metabolite (phenol). Analytical and bioanalytical chemistry, 387(7), pp. 2419-2424. Heidelberg: Springer 10.1007/s00216-006-0708-7
A reference material for the biological monitoring of occupational exposure to toluene, benzene and phenol was prepared. O-cresol and hippuric acid (metabolites of toluene) are used for the biological monitoring of occupational exposure to toluene. P
Publikováno v:
Accreditation and Quality Assurance. 11:231-235
The candidate reference material (RM) was prepared by freeze-drying pooled urine samples obtained from healthy persons occupationally exposed to toluene. Homogeneity testing yielded no significant differences of urinary concentrations of o-cresol and
Publikováno v:
Analytical and Bioanalytical Chemistry. 378:536-543
A rapid HPLC method for the determination of carboxylic acids in urine samples using a Chromolith Performance RP/18e 100/4.6 with Chromolith Guard Cartridge RP/18e 10/4.6 (Merck KgaA, Darmstadt, Germany) was developed. The method facilitates the simu
Publikováno v:
Accreditation and Quality Assurance. 8:113-116
A preliminary batch of the reference material was prepared by freeze-drying pooled urine samples obtained from healthy persons occupationally exposed to styrene. Tests for homogeneity and stability were performed by determining urine concentrations o
Publikováno v:
Fresenius' Journal of Analytical Chemistry. 361:756-760
Two batches of a reference material (RM) “total protein in human urine” were prepared for quality assurance in the determination of human urinary proteins. The material was prepared by freeze-drying of a pooled urine sample obtained from healthy
Autor:
Ludmila Dabrowská, Petra Mandikova, Jaroslav Mraz, František Kolář, Adéla Boudíková, Ivan Mikšík, Olga Popelová, Martin Štěrba, Vladimír Geršl, Jan Neckář
Publikováno v:
Canadian journal of physiology and pharmacology. 90(9)
Dexrazoxane (DEX), an inhibitor of topoisomerase II and intracellular iron chelator, is believed to reduce the formation of reactive oxygen species (ROS) and protects the heart from the toxicity of anthracycline antineoplastics. As ROS also play a ro
Autor:
Petra Mandikova, Petra Micova, Kristyna Kozichova, Ludmila Dabrowská, Jan Neckar, Frantisek Kolar
Publikováno v:
The FASEB Journal. 26