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Autor:
Ludmila C. daSilva, Barry S. Handwerger, Sergei P. Atamas, John C. Papadimitriou, Irina G. Luzina, Catherine E. Storrer, Garnett Kelsoe
Publikováno v:
Journal of Leukocyte Biology. 70:578-584
The mechanisms of autoantibody production are not well understood. Germinal centers (GC) may be important sites of immune disregulation in autoimmune diseases. In this study, we document the presence of spontaneous GC formation in the spleens of seve