Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ludmila A.G. Pinho"'
Autor:
Marcilio Cunha-Filho, Ludmila A.G. Pinho, Ricardo Neves Marreto, Guilherme M. Gelfuso, Tais Gratieri
Publikováno v:
Journal of Pharmacy and Pharmacology. 74:1391-1405
Objectives Three-dimensional printing (3DP) has opened the era of drug personalization, promising to revolutionize the pharmaceutical field with improvements in efficacy, safety and compliance of the treatments. As a result of these investigations, a
Granules of finasteride and cyclodextrin obtained by hot-melt extrusion to target the hair follicles
Autor:
Guilherme M. Gelfuso, Livia L. Sa-Barreto, Tais Gratieri, Ludmila A.G. Pinho, Stephania G.B. Lima, Marcilio Cunha-Filho
Publikováno v:
Powder Technology. 391:311-320
This study aimed to develop topical granules of finasteride (FIN) with a follicular targeting potential to treat androgenic alopecia. In this sense, FIN inclusion complexes with cyclodextrin produced by two different methods (nanospray-drying and rot
Autor:
Ludmila A.G. Pinho, Ana Luiza Lima, Livia L. Sa-Barreto, Guilherme M. Gelfuso, Tais Gratieri, Ricardo Neves Marreto, Yong Chen, Marcilio Cunha-Filho
Publikováno v:
International journal of pharmaceutics. 627
Aesthetic perforations are often associated with health issues, such as itching, inflammation, or microbial infection. Accordingly, this work proposed a lacquer to be applied on the adornment accessory forming a film from which a proper drug is relea
Preformulation Studies to Guide the Production of Medicines by Fused Deposition Modeling 3D Printing
Autor:
Ricardo Neves Marreto, Guilherme M. Gelfuso, Livia L. Sa-Barreto, Marcilio Cunha-Filho, Tais Gratieri, Ludmila A.G. Pinho, Ana Luiza Lima
Publikováno v:
AAPS PharmSciTech. 22
Fused deposition modeling (FDM) 3D printing has demonstrated high potential for the production of personalized medicines. However, the heating at high temperatures inherent to this process causes unknown risks to the drug product's stability. The pre
Autor:
Ludmila A.G. Pinho, Felipe Q. Pires, Izabel Cristina Rodrigues da Silva, Tais Gratieri, Marcilio Cunha-Filho, Daniel Oliveira Freire, Lúcio Cardozo-Filho, Livia L. Sa-Barreto, Guilherme M. Gelfuso
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 137:543-553
This study aimed to use thermal analysis and other analytical tools to guide the production of thymol (TML) and essential oil of Lippia origanoides (EO) solid inclusion complexes from a screening of different cyclodextrins (CDs) types and production
Autor:
Guilherme M. Gelfuso, Tais Gratieri, Ludmila A.G. Pinho, Marcilio Cunha-Filho, Ricardo Neves Marreto, Livia L. Sa-Barreto, Juliano A. Chaker, Ana Luiza Lima
Publikováno v:
Pharmaceutics
Pharmaceutics, Vol 12, Iss 779, p 779 (2020)
Volume 12
Issue 8
Pharmaceutics, Vol 12, Iss 779, p 779 (2020)
Volume 12
Issue 8
Here, we assessed the feasibility of hot-melt extrusion (HME) to obtain effervescent drug products for the first time. For this, a combined mixture design was employed using paracetamol as a model drug. Extrudates were obtained under reduced torque (
Autor:
Pedro A. Granados, Ludmila A.G. Pinho, Livia L. Sa-Barreto, Tais Gratieri, Guilherme M. Gelfuso, Marcilio Cunha-Filho
Publikováno v:
Advanced Powder Technology. 33:103380
Autor:
Livia L. Sa-Barreto, Ludmila A.G. Pinho, Marcilio Cunha-Filho, Caroline Garcia Ribeiro, Ana Claudia Temer
Publikováno v:
Infarma: Pharmaceutical Sciences, Vol 30, Iss 2, Pp 77-84 (2018)
Orodispersible tablets are getting popular due to its easy administration which leads to a higher therapeutic adherence. This study aimed to evaluate the state of the art of these drug products based on the scientific literature. Also, orodispersible
Autor:
Guilherme M. Gelfuso, Livia L. Sa-Barreto, Stephania G.B. Lima, Marcilio Cunha-Filho, Lorena F.B. Malaquias, Tais Gratieri, Ludmila A.G. Pinho, Felipe Q. Pires, Lúcio Cardozo-Filho
Publikováno v:
Chemical Engineering Research and Design. 132:1193-1201
The aim of this study was to improve the pharmaceutical properties of theobromine (TB), particularly its flowability and dissolution rate, by preparing solid dispersions using different technologies (hot melt extrusion—HME, freeze-drying—FD, and
Autor:
Izabel Cristina Rodrigues da Silva, Ludmila A.G. Pinho, Lucindo José Quintans-Júnior, Livia L. Sa-Barreto, Marlange A. Oliveira, Jullyana S.S. Quintans, Tais Gratieri, Guilherme M. Gelfuso, Ricardo Neves Marreto, Marcilio Cunha-Filho
Publikováno v:
Carbohydrate polymers. 231
The flavonoid naringenin (NAR) exhibits an outstanding anti-inflammatory potential; however, stability problems and reduced solubility hinder its commercial insertion. This work aimed to obtain solid-state hydroxypropyl-β-cyclodextrin (CD) inclusion