Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Ludek Eyer"'
Autor:
Branislav Kovacech, Lubica Fialova, Peter Filipcik, Rostislav Skrabana, Monika Zilkova, Natalia Paulenka-Ivanovova, Andrej Kovac, Denisa Palova, Gabriela Paulikova Rolkova, Katarina Tomkova, Natalia Turic Csokova, Karina Markova, Michaela Skrabanova, Kristina Sinska, Neha Basheer, Petra Majerova, Jozef Hanes, Vojtech Parrak, Michal Prcina, Ondrej Cehlar, Martin Cente, Juraj Piestansky, Michal Fresser, Michal Novak, Monika Slavikova, Kristina Borsova, Viktoria Cabanova, Bronislava Brejova, Tomas Vinař, Jozef Nosek, Boris Klempa, Ludek Eyer, Vaclav Hönig, Martin Palus, Daniel Ruzek, Tereza Vyhlidalova, Petra Strakova, Blanka Mrazkova, Dagmar Zudova, Gizela Koubkova, Vendula Novosadova, Jan Prochazka, Radislav Sedlacek, Norbert Zilka, Eva Kontsekova
Publikováno v:
EBioMedicine, Vol 76, Iss , Pp 103818- (2022)
Summary: Background: The emergence of new SARS-CoV-2 variants of concern B.1.1.7 (Alpha), B.1.351 (Beta), P.1 (Gamma) and B.1.617.2 (Delta) that harbor mutations in the viral S protein raised concern about activity of current vaccines and therapeutic
Externí odkaz:
https://doaj.org/article/d503988bb92a4f8ca2f39b041da95550
Autor:
Michal Stefanik, Petra Formanova, Tomas Bily, Marie Vancova, Ludek Eyer, Martin Palus, Jiri Salat, Carla Torres Braconi, Paolo M. de A. Zanotto, Ernest A. Gould, Daniel Ruzek
Publikováno v:
BMC Neuroscience, Vol 19, Iss 1, Pp 1-8 (2018)
Abstract Background The recent Zika virus (ZIKV) outbreak has linked ZIKV with microcephaly and other central nervous system pathologies in humans. Astrocytes are among the first cells to respond to ZIKV infection in the brain and are also targets fo
Externí odkaz:
https://doaj.org/article/748f68f6f4dd408580147310db270e53
Publikováno v:
Microorganisms, Vol 9, Iss 3, p 471 (2021)
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a causative agent of the pandemic coronavirus disease 2019 (COVID-19), which has resulted in over two million deaths worldwide to date. Diphyllin and diphyllinosides are known as natural
Externí odkaz:
https://doaj.org/article/2f6fab6b65da4bf48d4cfa8868b6c4a9
Autor:
Michal Stefanik, Fortunatus C Ezebuo, Jan Haviernik, Ikemefuna C. Uzochukwu, Martina Fojtikova, Jiri Salat, Ludek Eyer, Daniel Ruzek
Publikováno v:
Proceedings, Vol 50, Iss 1, p 6 (2020)
Arthropod-borne flaviviruses such as tick-borne encephalitis virus (TBEV), West Nile virus (WNV), Zika virus (ZIKV), Dengue virus (DENV), and yellow fever virus (YFV) cause several serious life-threatening syndromes (encephalitis, miscarriages, paral
Externí odkaz:
https://doaj.org/article/5ba585406cd647bea0d0bed8bca90834
Autor:
Jan Haviernik, Ludek Eyer, Antoine Nougairède, Marie Uhlířová, Jean-Sélim Driouich, Darina Zouharová, James Jason Valdés, Ernest Gould, Erik De Clercq, Xavier de Lamballerie, Daniel Ruzek
Publikováno v:
Proceedings, Vol 50, Iss 1, p 12 (2020)
Tick-borne encephalitis virus (TBEV) is a pathogen that causes severe human neuroinfections in Europe and Asia for which there is currently no specific therapy. The adenosine analogue galidesivir (BCX4430), a broad-spectrum RNA virus inhibitor, has e
Externí odkaz:
https://doaj.org/article/6e3341d7d4ed4d5187eeb0abbf4af128
Autor:
Michal Stefanik, James J. Valdes, Fortunatus C. Ezebuo, Jan Haviernik, Ikemefuna C. Uzochukwu, Martina Fojtikova, Jiri Salat, Ludek Eyer, Daniel Ruzek
Publikováno v:
Microorganisms, Vol 8, Iss 4, p 599 (2020)
Vector-borne flaviviruses (VBFs) affect human health worldwide, but no approved drugs are available specifically to treat VBF-associated infections. Here, we performed in silico screening of a library of U.S. Food and Drug Administration-approved ant
Externí odkaz:
https://doaj.org/article/aeee10316a554a17882b166a2eaec000
Autor:
Jiri Salat, Kamil Mikulasek, Osmany Larralde, Petra Pokorna Formanova, Ales Chrdle, Jan Haviernik, Jana Elsterova, Dana Teislerova, Martin Palus, Ludek Eyer, Zbynek Zdrahal, Juraj Petrik, Daniel Ruzek
Publikováno v:
Vaccines, Vol 8, Iss 1, p 81 (2020)
Vaccination against tick-borne encephalitis (TBE) is based on the use of formalin-inactivated, culture-derived whole-virus vaccines. Immune response following vaccination is primarily directed to the viral envelope (E) protein, the major viral surfac
Externí odkaz:
https://doaj.org/article/d7efa593a6a34f31bc9b934ddefe33fb
Publikováno v:
Antiviral research.
Tick-borne encephalitis (TBE) is a potentially fatal disease common in much of Europe and Asia. There is no specific therapy for the treatment of TBE patients. However, several efforts are being made to develop small molecules that specifically inter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa835d9987d0762b27ab312e1015000d
https://pubmed.ncbi.nlm.nih.gov/36574904
https://pubmed.ncbi.nlm.nih.gov/36574904
Autor:
Pavel Svoboda, Haoqi Wang, Jiri Salat, Varun Gejji, Sandun Fernando, Ludek Eyer, Michal Stefanik, Daniel Ruzek
Publikováno v:
Virology. 546:13-19
Tick-borne encephalitis virus (TBEV) is a medically important representative of the Flaviviridae family. The TBEV genome encodes a single polyprotein, which is co/post-translationally cleaved into three structural and seven non-structural proteins. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24c1cf66e9a45171b2bbb88b61bbea4f
https://doi.org/10.1016/j.virol.2020.03.006
https://doi.org/10.1016/j.virol.2020.03.006
Publikováno v:
Annual Reports in Medicinal Chemistry ISBN: 9780323988933
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::623b6319b08259d7de4ad7db48aaf3ae
https://doi.org/10.1016/bs.armc.2022.08.003
https://doi.org/10.1016/bs.armc.2022.08.003
