Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Luda Khait"'
Publikováno v:
Artificial Organs. 35:69-74
Cardiovascular disease is one of the leading causes of death in the United States, and new treatments need to be developed in order to provide novel therapies. Tissue engineering aims to develop biologic substitutes that restore tissue function. The
Autor:
Edward L. Bove, Luda Khait, Chani J. Hodonsky, John A. Shaw, Bedabrata Sarkar, Jan A. Nolta, Claus S. Sondergaard, Ming-Sing Si, Ravi K. Birla
Publikováno v:
The Annals of Thoracic Surgery. 90:796-804
Background Mesenchymal stromal cells have been recently isolated from thymus gland tissue discarded after surgical procedures. The role of this novel cell type in heart regeneration has yet to be defined. The purpose of this study was to evaluate the
Publikováno v:
Journal of Bioscience and Bioengineering. 107:183-190
Research in the area of cardiac tissue engineering is focused on the development of functional 3-dimensional cardiac muscle tissue in vitro , which includes bioengineered cardiac patches, pumps and ventricles. One of the major challenges in the field
Publikováno v:
ASAIO Journal. 54:284-294
Tissue engineering strategies are being used to develop functional 3D heart muscle in vitro. Work within our own group has been focused on the development of bioengineered heart muscle using fibrin gel as a support matrix. As tissue engineering model
Publikováno v:
Annals of Biomedical Engineering. 36:713-725
Tissue-engineered constructs have high metabolic requirements during in vitro culture necessitating the development of micro-perfusion systems to maintain high functional performance. In this study, we describe the design, fabrication, and testing of
Autor:
Ravi K. Birla, Nicole R. Blan, Francesco Migneco, Garrett N. Coyan, Louise Hecker, Luda Khait, Yen-Chih Huang
Publikováno v:
Journal of Cardiovascular Translational Research. 1:71-84
Cardiovascular disease affects 80 million people in the USA and is the leading cause of death. Significant limitations of current treatments necessitate the development of novel strategies. Cardiovascular tissue engineering is an emerging field focus
Publikováno v:
Journal of Biomedical Materials Research Part A. :719-731
Tissue engineered heart muscle may be able to provide a treatment modality for early stage congestive heart failure. In this study, we describe a new method to engineer functional 3-dimensional heart muscle utilizing a biodegradable fibrin gel. Prima
Publikováno v:
Artificial organs. 35(1)
Cardiovascular disease is one of the leading causes of death in the United States, and new treatments need to be developed in order to provide novel therapies. Tissue engineering aims to develop biologic substitutes that restore tissue function. The
Autor:
Luda Khait, Ravi K. Birla
Publikováno v:
Artificial organs. 33(1)
A three-dimensional bioengineered heart muscle (BEHM) construct model had been previously developed, exhibiting contractile forces up to 800 microN. The interest of this study was to determine gene expression levels of biologic markers involved in ca
Publikováno v:
Zebrafish. 5(4)
Traditional working heart preparations, based on the original Langendorff setup, are widely used experimental models that have tremendously advanced the cardiovascular field. However, these systems can be deceivingly complex, requiring the maintenanc