Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Lucy Vulchanova"'
Autor:
Caroline C. Churchill, Cristina D. Peterson, Kelley F. Kitto, Kelsey R. Pflepsen, Lalitha R. Belur, R. Scott McIvor, Lucy Vulchanova, George L. Wilcox, Carolyn A. Fairbanks
Publikováno v:
Frontiers in Pain Research, Vol 4 (2024)
Agmatine, a decarboxylated form of L-arginine, prevents opioid analgesic tolerance, dependence, and self-administration when given by both central and systemic routes of administration. Endogenous agmatine has been previously detected in the central
Externí odkaz:
https://doaj.org/article/52efa26146094fbbb8d8e7459e96d505
Autor:
Reshma Gore, Tina Esmail, Kelsey Pflepsen, Ezequiel Marron Fernandez de Velasco, Kelley F. Kitto, Maureen S. Riedl, Andrea Karlen, R. Scott McIvor, Christopher N. Honda, Carolyn A. Fairbanks, Lucy Vulchanova
Publikováno v:
Frontiers in Pain Research, Vol 4 (2023)
Investigation of neural circuits underlying visceral pain is hampered by the difficulty in achieving selective manipulations of individual circuit components. In this study, we adapted a dual AAV approach, used for projection-specific transgene expre
Externí odkaz:
https://doaj.org/article/267d366a68584b458e50530348ee8317
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/7a33ee52d4f34d1eb1a324eabdeec4bf
Autor:
Roman Tyshynsky, Sulagna Sensarma, Maureen Riedl, John Bukowy, Lawrence P. Schramm, Lucy Vulchanova, John W. Osborn
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Recent studies using a novel method for targeted ablation of afferent renal nerves have demonstrated their importance in the development and maintenance of some animal models of hypertension. However, relatively little is known about the anatomy of r
Externí odkaz:
https://doaj.org/article/ca703bd5a7154587a66cefc9ddbcbaf9
Autor:
Alexander G. J. Skorput, Reshma Gore, Rachel Schorn, Maureen S. Riedl, Ezequiel Marron Fernandez de Velasco, Bailey Hadlich, Kelley F. Kitto, Carolyn A. Fairbanks, Lucy Vulchanova
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Adeno-associated viral (AAV) vectors allow for site-specific and time-dependent genetic manipulation of neurons. However, for successful implementation of AAV vectors, major consideration must be given to the selection of viral serotype and route of
Externí odkaz:
https://doaj.org/article/6fb643af031c48b9a9569490d07460b9
Autor:
Lalitha R. Belur, Megan Romero, Junggu Lee, Kelly M. Podetz-Pedersen, Zhenhong Nan, Maureen S. Riedl, Lucy Vulchanova, Kelley F. Kitto, Carolyn A. Fairbanks, Karen F. Kozarsky, Paul J. Orchard, William H. Frey, Walter C. Low, R. Scott McIvor
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Mucopolysaccharidosis type I (MPS I) is an inherited metabolic disorder caused by deficiency of the lysosomal enzyme alpha-L-iduronidase (IDUA). The two current treatments [hematopoietic stem cell transplantation (HSCT) and enzyme replacement therapy
Externí odkaz:
https://doaj.org/article/612b20e3a1914626b04655208aae2b85
Autor:
Cristina D. Peterson, Jonathan J. Waataja, Kelley F. Kitto, Samuel J. Erb, Harsha Verma, Daniel J. Schuster, Caroline C. Churchill, Maureen S. Riedl, Lalitha R. Belur, Daniel A. Wolf, R. Scott McIvor, Lucy Vulchanova, George L. Wilcox, Carolyn A. Fairbanks
Publikováno v:
Molecular Therapy. 31:1123-1135
Autor:
Lalitha R. Belur, Kelly M. Podetz-Pedersen, Thuy An Tran, Joshua A. Mesick, Nathaniel M. Singh, Maureen Riedl, Lucy Vulchanova, Karen F. Kozarsky, R. Scott McIvor
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 24, Iss , Pp 100604- (2020)
Mucopolysaccharidosis type I (MPS I) is an inherited metabolic disorder caused by deficiency of alpha-L-iduronidase (IDUA), resulting in accumulation of heparan and dermatan sulfate glycosaminoglycans (GAGs). Individuals with the most severe form of
Externí odkaz:
https://doaj.org/article/5bed40c4b92e49d5a837dddbf675bf7e
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Clinical and preclinical studies have revealed that local administration of opioid agonists into peripheral tissue attenuates inflammatory pain. However, few studies have examined whether peripherally restricted opioids are effective in reducing mech
Externí odkaz:
https://doaj.org/article/3ed81c59b994477193b43c41c30407aa
Autor:
Tongzhen Xie, Rachel E. Schorn, Cristina D. Peterson, Lucy Vulchanova, George L. Wilcox, Carolyn A. Fairbanks
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.