Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lucy Sanchez-Covarrubias"'
Autor:
Lucy Sanchez-Covarrubias, Lauren M Slosky, Brandon J Thompson, Yifeng Zhang, Mei-Li Laracuente, Kristin M DeMarco, Patrick T Ronaldson, Thomas P Davis
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88516 (2014)
Our laboratory has previously demonstrated that peripheral inflammatory pain (PIP), induced by subcutaneous plantar injection of λ-carrageenan, results in increased expression and activity of the ATP-dependent efflux transporter P-glycoprotein (P-gp
Externí odkaz:
https://doaj.org/article/fd44c9292b344d9f9cf6f3bbff866d47
Autor:
Patrick T. Ronaldson, Lucy Sanchez-Covarrubias, Lauren M. Slosky, Brandon J. Thompson, Yifeng Zhang, Mei Li Laracuente
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 34:699-707
Cerebral hypoxia and subsequent reoxygenation stress (H/R) is a component of several diseases. One approach that may enable neural tissue rescue after H/R is central nervous system (CNS) delivery of drugs with brain protective effects such as 3-hydro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef7ef1edadff4f84703f20e07b886094
https://doi.org/10.1038/jcbfm.2014.4
https://doi.org/10.1038/jcbfm.2014.4
Autor:
Patrick T. Ronaldson, Mei Li Laracuente, Thomas P. Davis, Kristen Demarco, William D. Staatz, Gwen McCaffrey, Jessica D. Finch, Lucy Sanchez-Covarrubias
Publikováno v:
Journal of Neurochemistry. 122:962-975
P-glycoprotein (ABCB1/MDR1, EC 3.6.3.44), the major efflux transporter at the blood-brain barrier (BBB), is a formidable obstacle to CNS pharmacotherapy. Understanding the mechanism(s) for increased P-glycoprotein activity at the BBB during periphera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c40939c2e0b53811fa1712947d6240f
https://doi.org/10.1111/j.1471-4159.2012.07831.x
https://doi.org/10.1111/j.1471-4159.2012.07831.x
Autor:
Jeffrey J. Lochhead, Kristin M. DeMarco, Lucy Sanchez-Covarrubias, Jessica D. Finch, Colleen E. Quigley, Gwen McCaffrey, Thomas P. Davis, Patrick T. Ronaldson
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 302:H582-H593
Our laboratory has shown that λ-carrageenan-induced peripheral inflammatory pain (CIP) can alter tight junction (TJ) protein expression and/or assembly leading to changes in blood-brain barrier xenobiotic permeability. However, the role of reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd781906543b09aaee7fba4d14b06b63
https://doi.org/10.1152/ajpheart.00889.2011
https://doi.org/10.1152/ajpheart.00889.2011
Autor:
Lauren M. Slosky, Thomas P. Davis, Patrick T. Ronaldson, Lucy Sanchez-Covarrubias, Brandon J. Thompson, Mei Li Laracuente, Yifeng Zhang, Todd W. Vanderah
Effective pharmacologic treatment of pain with opioids requires that these drugs attain efficacious concentrations in the central nervous system (CNS). A primary determinant of CNS drug permeation is P-glycoprotein (P-gp), an endogenous blood-brain b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7904aac5c4bae1e963d3d42a447a5e68
https://europepmc.org/articles/PMC3807077/
https://europepmc.org/articles/PMC3807077/
Autor:
Patrick T. Ronaldson, Lucy Sanchez-Covarrubias, Brandon J. Thompson, Lauren M. Slosky, Yifeng Zhang, Thomas P. Davis, Mei Li Laracuente, Kristin M. DeMarco
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 2, p e88516 (2014)
PLoS ONE, Vol 9, Iss 2, p e88516 (2014)
Our laboratory has previously demonstrated that peripheral inflammatory pain (PIP), induced by subcutaneous plantar injection of λ-carrageenan, results in increased expression and activity of the ATP-dependent efflux transporter P-glycoprotein (P-gp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4475b7481b8aa89a0b220cc0cde2ea4d
https://pubmed.ncbi.nlm.nih.gov/24520393
https://pubmed.ncbi.nlm.nih.gov/24520393
Publikováno v:
The FASEB Journal. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d47f39dfee0316e4acdd84ad76d2f049
https://doi.org/10.1096/fasebj.26.1_supplement.862.5
https://doi.org/10.1096/fasebj.26.1_supplement.862.5
Autor:
Kristin M. DeMarco, Lucy Sanchez-Covarrubias, Thomas P. Davis, Christine M Solinsky, Patrick T. Ronaldson
Our laboratory has shown that peripheral inflammatory pain induced by λ-carrageenan (CIP) can increase blood-brain barrier (BBB) permeability and alter tight junction (TJ) protein expression leading to changes in BBB functional integrity. However, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::512610f08d9279e886d4cc1a3dbf8c92
https://europepmc.org/articles/PMC3910515/
https://europepmc.org/articles/PMC3910515/
Autor:
Patrick T. Ronaldson, Thomas P. Davis, Lucy Sanchez-Covarrubias, Lauren M. Slosky, Brandon J. Thompson
Publikováno v:
ResearcherID
The blood-brain barrier (BBB) and blood-cerebrospinal fluid (BCSF) barriers are critical determinants of CNS homeostasis. Additionally, the BBB and BCSF barriers are formidable obstacles to effective CNS drug delivery. These brain barrier sites expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf946c2acf4df8c711d0e0f18c1c0d54
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000334311000002&KeyUID=WOS:000334311000002
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000334311000002&KeyUID=WOS:000334311000002
Autor:
Sanchez-Covarrubias, Lucy1, Slosky, Lauren M.1, Thompson, Brandon J.1, Zhang, Yifeng1, Laracuente, Mei-Li1, DeMarco, Kristin M.1, Ronaldson, Patrick T.1, Davis, Thomas P.1 davistp@email.arizona.edu
Publikováno v:
PLoS ONE. Feb2014, Vol. 9 Issue 2, p1-11. 11p.