Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Lucy R. Forrest"'
Autor:
LUCY R. FORREST
Publikováno v:
Dev Sanskriti: Interdisciplinary International Journal, Vol 6 (2015)
This theoretical paper is an attempt at exploring and understanding the convoluted concept of “suffering” according to the Indian philosophy, including Buddha, Patanjali, Sivananda, the Gita & Jainism. However, the three predominant schools of th
Externí odkaz:
https://doaj.org/article/7be3893c6566496ab13c729ba90a1f1c
Autor:
René Staritzbichler, Edoardo Sarti, Emily Yaklich, Antoniya Aleksandrova, Marcus Stamm, Kamil Khafizov, Lucy R Forrest
Publikováno v:
PLoS ONE, Vol 16, Iss 4, p e0239881 (2021)
The alignment of primary sequences is a fundamental step in the analysis of protein structure, function, and evolution, and in the generation of homology-based models. Integral membrane proteins pose a significant challenge for such sequence alignmen
Externí odkaz:
https://doaj.org/article/98f0fed9026c444f86ee7c4fc3c06488
Autor:
Katherine E Huffer, Antoniya A Aleksandrova, Andrés Jara-Oseguera, Lucy R Forrest, Kenton J Swartz
Publikováno v:
eLife, Vol 9 (2020)
The recent proliferation of published TRP channel structures provides a foundation for understanding the diverse functional properties of this important family of ion channel proteins. To facilitate mechanistic investigations, we constructed a struct
Externí odkaz:
https://doaj.org/article/76a3f39f1b384dc092a8fd5a535a5edd
Autor:
Wenchang Zhou, Giacomo Fiorin, Claudio Anselmi, Hossein Ali Karimi-Varzaneh, Horacio Poblete, Lucy R Forrest, José D Faraldo-Gómez
Publikováno v:
eLife, Vol 8 (2019)
That channels and transporters can influence the membrane morphology is increasingly recognized. Less appreciated is that the extent and free-energy cost of these deformations likely varies among different functional states of a protein, and thus, th
Externí odkaz:
https://doaj.org/article/096e5ea06b6849bc94922f1e580317a3
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217377 (2019)
The human serotonin transporter hSERT facilitates the reuptake of its endogenous substrate serotonin from the synaptic cleft into presynaptic neurons after signaling. Reuptake regulates the availability of this neurotransmitter and therefore hSERT pl
Externí odkaz:
https://doaj.org/article/26d79fffd7bc4a658aa10e93d1c8c36b
Publikováno v:
NEUROCHEMICAL RESEARCH, 47(1), 163-175. SPRINGER/PLENUM PUBLISHERS
Neurochemical Research
Neurochem Res
Neurochemical Research
Neurochem Res
Excitatory amino acid transporters (EAAT) play a key role in glutamatergic synaptic communication. Driven by transmembrane cation gradients, these transporters catalyze the reuptake of glutamate from the synaptic cleft once this neurotransmitter has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61801d652faacd31ea92958ac1713716
https://doi.org/10.1007/s11064-021-03253-w
https://doi.org/10.1007/s11064-021-03253-w
Publikováno v:
bioRxiv
All lipid membranes have inherent morphological preferences and resist deformation. Yet adaptations in membrane shape can and do occur at multiple length scales. While this plasticity is crucial for cellular physiology, the factors controlling the mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95307312c340b64623a07060c1aa6cbd
https://doi.org/10.1101/2023.02.02.525347
https://doi.org/10.1101/2023.02.02.525347
Autor:
Kyle C. Kihn, Richard T. Bradshaw, Tyree Wilson, Daniel Deredge, Lucy R. Forrest, Patrick L. Wintrode, Angela Wilks, Ally K. Smith
Publikováno v:
Biophys J
The cytoplasmic heme binding protein from Pseudomonas aeruginosa, PhuS, plays two essential roles in regulating heme uptake and iron homeostasis. First, PhuS shuttles exogenous heme to heme oxygenase (HemO) for degradation and iron release. Second, P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ecd9bee1062697cfde6f77f85fac48
https://doi.org/10.1016/j.bpj.2021.11.010
https://doi.org/10.1016/j.bpj.2021.11.010
Autor:
Vanessa Leone, Richard T. Bradshaw, Caroline Koshy, Paul Suhwan Lee, Cristina Fenollar-Ferrer, Veronika Heinz, Christine Ziegler, Lucy R. Forrest
Membrane transporters mediate the passage of molecules across membranes and are essential for cellular function. While the transmembrane region of these proteins is responsible for substrate transport, often the cytoplasmic regions are required for m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d09239865b721eb31e1e6f93f1ff45fd
https://doi.org/10.1101/2022.06.05.494857
https://doi.org/10.1101/2022.06.05.494857
Autor:
René Staritzbichler, Emily Yaklich, Edoardo Sarti, Nikola Ristic, Peter W Hildebrand, Lucy R Forrest
Publikováno v:
Nucleic Acids Res
Nucleic Acids Research
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac391⟩
Nucleic Acids Research
Nucleic Acids Research, 2022, ⟨10.1093/nar/gkac391⟩
The AlignMe web server is dedicated to accurately aligning sequences of membrane proteins, a particularly challenging task due to the strong evolutionary divergence and the low compositional complexity of hydrophobic membrane-spanning proteins. Align
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad6f47c61a806924d144cfa8eee53d2c
https://pubmed.ncbi.nlm.nih.gov/35609986
https://pubmed.ncbi.nlm.nih.gov/35609986