Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lucy Quach"'
Autor:
Ying Zhu, Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Maia Vinogradova, Robert B DuBridge, Chad May
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 6 (2022)
Externí odkaz:
https://doaj.org/article/c0d4502e962a41b08a1e2dfef4485839
Autor:
Danielle E Dettling, Eilene Kwok, Lucy Quach, Aakash Datt, Jeremiah D Degenhardt, Anand Panchal, Pui Seto, Jessica L Krakow, Russell Wall, Brian J Hillier, Ying Zhu, Maia Vinogradova, Robert B DuBridge, Chad May
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004336
BackgroundDespite clinical success with T cell engagers (TCEs) targeting hematological malignancies, achieving a safe and efficacious dose in patients with solid tumors remains challenging. Due to potency, low levels of target antigen expression on n
Autor:
Ying Zhu, Lucy Quach, Robert B. Dubridge, Maia Vinogradova, Jeremiah D. Degenhardt, Anand Panchal, Chad May, Danielle E. Dettling, Pui Seto, Aakash Datt, Russell Wall, Jessica L. Krakow, Brian J. Hillier, Eilene Kwok
Publikováno v:
Cancer Research. 79:557-557
Despite clinical success with bispecific antibodies (bsAbs) targeting hematological malignancies (e.g. blinatumomab, a CD19xCD3 bsAb), efficacy in solid tumor indications remains a significant challenge. Because T cell redirecting bsAbs are so potent
Autor:
Sebastien Monette, Ronald G. Crystal, Jonathan B. Rosenberg, Todd K. Rosengart, Benjamin Van de Graaf, Stephen M. Kaminsky, Jason G. Mezey, Stacey Chen, Lucy Quach, Dolan Sondhi, Lorraine Pierre-Destine, Bishnu P. De, Neil R. Hackett
Publikováno v:
Human Gene Therapy Clinical Development. 24:38-46
Coronary artery disease (CAD), a leading cause of mortality, is a chronic disease in which blood flow to the myocardium is obstructed, leading to ischemia. Although coronary artery stenting and surgical bypass are successful with localized coronary l
Autor:
Lauren M. Beatty, Donald J. D'Amico, Szilard Kiss, Ronald G. Crystal, Nicolas A. Yannuzzi, Lucy Quach, Michael A. Klufas, Stephen M. Kaminsky
Publikováno v:
JAMA ophthalmology. 133(1)
Bevacizumab acquired from compounding pharmacies for intravitreal injection may cause infectious and noninfectious inflammation. In addition to safety issues, the drug itself may have variable efficacy associated with product aliquoting, handling, an
Autor:
Jonathan B. Rosenberg, Lauren M. Beatty, David F. Havlicek, Ronald G. Crystal, Stephen M. Kaminsky, Sebastien Monette, Bishnu P. De, Lucy Quach, Dolan Sondhi
Publikováno v:
Molecular Therapy. 23:S180-S181
Cocaine is a highly addictive drug with significant social, societal, economic and medical impact, yet there are no effective therapies for cocaine addiction. An anti-cocaine vaccine that could evoke antibodies to bind the drug and prevent its transf
Autor:
Stephanie Rhee, Ronald G. Crystal, Salim Bougarn, Stefan Worgall, Esther Z Frenk, Lucy Quach, Stephen M. Kaminsky, Wenzhu Wu, Amal Robay, Maria J. Chiuchiolo
Publikováno v:
Molecular Therapy. 23:S22-S23
We have developed a platform technology against infectious agents that mediates both passive and active immunity, with rapid, passive protection through the genetic delivery of an anti-pathogen monoclonal antibody together with long term protective a
Autor:
Bishnu P. De, Ronald G. Crystal, Jonathan B. Rosenberg, Dolan Sondhi, Carol Russo, Lucy Quach, Stephen M. Kaminsky
Publikováno v:
Molecular Therapy. 24:S187
Based on the knowledge that, when administered intravenously (IV), 90% of adeno-associated virus (AAV) gene transfer vectors are transferred to the liver, the IV route has become the standard for gene therapy applications directed toward genetic modi
Autor:
Stephen Kaminsky, Lucy Quach, Stacy Chen, Benjamin Van de Graaf, Sebastien Monette, Jonathan Rosenberg, Bishnu De, Dolan Sondhi, Neil Hackett, Jason Mezey, Todd Ronsengart, Ronald Crystal
Publikováno v:
Human Gene Therapy Clinical Development. :130514071334005