Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lucy Nirschl"'
Autor:
Mathias Linnerbauer, Tobias Beyer, Lucy Nirschl, Daniel Farrenkopf, Lena Lößlein, Oliver Vandrey, Anne Peter, Thanos Tsaktanis, Hania Kebir, David Laplaud, Rupert Oellinger, Thomas Engleitner, Jorge Ivan Alvarez, Roland Rad, Thomas Korn, Bernhard Hemmer, Francisco J. Quintana, Veit Rothhammer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Multiple Sclerosis (MS) is a chronic autoimmune inflammatory disorder of the central nervous system (CNS). Current therapies mainly target inflammatory processes during acute stages, but effective treatments for progressive MS are limited. I
Externí odkaz:
https://doaj.org/article/5f7fdf63aa804452bff90537ad8c51b1
Autor:
Mathias Linnerbauer, Lena Lößlein, Oliver Vandrey, Thanos Tsaktanis, Alexander Beer, Ulrike J. Naumann, Franziska Panier, Tobias Beyer, Lucy Nirschl, Joji B. Kuramatsu, Jürgen Winkler, Francisco J. Quintana, Veit Rothhammer
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the CNS that is characterized by demyelination and axonal degeneration. Although several established treatments reduce relapse burden, effective treatments to halt chronic progression a
Externí odkaz:
https://doaj.org/article/7bdc9d38b2d8495e858ff11e9bf9ca2f
Autor:
Christopher Sie, Ravi Kant, Christian Peter, Andreas Muschaweckh, Monika Pfaller, Lucy Nirschl, Helena Domínguez Moreno, Tereza Chadimová, Gildas Lepennetier, Tanja Kuhlmann, Rupert Öllinger, Thomas Engleitner, Roland Rad, Thomas Korn
Publikováno v:
The Journal of experimental medicine. 219(8)
In certain instances, Th17 responses are associated with severe immunopathology. T cell–intrinsic mechanisms that restrict pathogenic effector functions have been described for type 1 and 2 responses but are less well studied for Th17 cells. Here,
Autor:
Thanos Tsaktanis, Bernhard Hemmer, Lucy Nirschl, Mathias Linnerbauer, Veit Rothhammer, Verena Grummel, Lena Loesslein, Till Andlauer, Francisco J. Quintana, Tobias Beyer, Ana Cirac
Publikováno v:
Neurol Neuroimmunol Neuroinflamm
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
ObjectiveTo evaluate the aryl hydrocarbon receptor (AHR)-dependent transforming growth factor alpha (TGF-α)/vascular endothelial growth factor B (VEGF-B) ratio, which regulates the effects of metabolic, dietary, and microbial factors on acute and ch
Aryl Hydrocarbon Receptor Plasma Agonist Activity Correlates With Disease Activity in Progressive MS
Autor:
Lucy Nirschl, Tobias Beyer, Veit Rothhammer, Thanos Tsaktanis, Verena Grummel, Mathias Bussas, Bernhard Hemmer, Mathias Linnerbauer, Thomas Korn, Emily C. Tjon, Francisco J. Quintana, Mark Mühlau
Publikováno v:
Neurology® Neuroimmunology & Neuroinflammation
article-version (Version of Record) 3
article-version (Version of Record) 3
ObjectiveThe relationship between serum aryl hydrocarbon receptor (AHR) agonistic activity levels with disease severity, its modulation over the course of relapsing-remitting MS (RRMS), and its regulation in progressive MS (PMS) are unknown. Here, we
Autor:
Mathias Linnerbauer, Lena Lößlein, Oliver Vandrey, Thanos Tsaktanis, Alexander Beer, Ulrike J. Naumann, Franziska Panier, Tobias Beyer, Lucy Nirschl, Joji B. Kuramatsu, Jürgen Winkler, Francisco J. Quintana, Veit Rothhammer
Publikováno v:
JCI Insight
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the CNS that is characterized by demyelination and axonal degeneration. Although several established treatments reduce relapse burden, effective treatments to halt chronic progression a