Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lucy M Collins"'
Autor:
Janelle Drouin‐Ouellet, Shong Lau, Per Ludvik Brattås, Daniella Rylander Ottosson, Karolina Pircs, Daniela A Grassi, Lucy M Collins, Romina Vuono, Annika Andersson Sjöland, Gunilla Westergren‐Thorsson, Caroline Graff, Lennart Minthon, Håkan Toresson, Roger A Barker, Johan Jakobsson, Malin Parmar
Publikováno v:
EMBO Molecular Medicine, Vol 9, Iss 8, Pp 1117-1131 (2017)
Abstract Direct conversion of human fibroblasts into mature and functional neurons, termed induced neurons (iNs), was achieved for the first time 6 years ago. This technology offers a promising shortcut for obtaining patient‐ and disease‐specific
Externí odkaz:
https://doaj.org/article/e73f830423c14f13b05bd7371e571788
Publikováno v:
F1000Research, Vol 6 (2018)
Background: Recently, the development of Parkinson’s disease (PD) has been linked to a number of genetic risk factors, of which the most common is glucocerebrosidase (GBA) mutations. Methods: We investigated PD and Gaucher Disease (GD) patient deri
Externí odkaz:
https://doaj.org/article/24b39195fdd84fed8c997b7ab823e3e4
Autor:
Timothy M. Cox, Lucy M Collins, Caroline H. Williams-Gray, Patrick Deegan, Roger A. Barker, Elizabeth R. Morris
Publikováno v:
Journal of Neurology
We report the cognitive features and progression of Parkinson's disease (PD) in five patients with concurrent Gaucher disease. The patients presented at an earlier age than patients with sporadic PD, as previously noted by others; but in contrast to
Publikováno v:
Prescriber. 26:16-23
Treatment for Parkinson's should be tailored to the needs of the patient and adjusted regularly to ensure maximum efficacy and tolerability. Our drug review outlines diagnosis, drug options and advanced therapies, and the management of complications,
Publikováno v:
F1000Research
Background: Recently, the development of Parkinson’s disease (PD) has been linked to a number of genetic risk factors, of which the most common is glucocerebrosidase (GBA) mutations. Methods: We investigated PD and Gaucher Disease (GD) patient deri
Autor:
Per Ludvik Brattås, Daniella Rylander Ottosson, Romina Vuono, Lucy M Collins, Lennart Minthon, Janelle Drouin-Ouellet, Johan Jakobsson, Annika Andersson Sjöland, Daniela A. Grassi, Caroline Graff, Shong Lau, Malin Parmar, Håkan Toresson, Roger A. Barker, Karolina Pircs, Gunilla Westergren-Thorsson
Publikováno v:
BASE-Bielefeld Academic Search Engine
EMBO Molecular Medicine
EMBO Molecular Medicine
Direct conversion of human fibroblasts into mature and functional neurons, termed induced neurons (iNs), was achieved for the first time 6 years ago. This technology offers a promising shortcut for obtaining patient‐ and disease‐specific neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17c821b0e0bcf5dd008b2082f6af5029
https://kar.kent.ac.uk/78971/1/Drouin-Ouellet_et_al-2017-EMBO_Molecular_Medicine.pdf
https://kar.kent.ac.uk/78971/1/Drouin-Ouellet_et_al-2017-EMBO_Molecular_Medicine.pdf
Autor:
Natalie Valle Guzman, Lucy M Collins, Adrian Y K Tan, Gemma Cummins, Sarah L Mason, Roger A. Barker, Faye Begeti
Publikováno v:
Journal of Neurology. 260:2777-2785
Cognitive features, which begin before manifestation of the motor features, are an integral part of Huntington's disease and profoundly affect quality of life. A number of neuropsychological batteries have been used to assess this aspect of the condi
Publikováno v:
Frontiers in Psychiatry
Cognitive dysfunction is a common feature of Parkinson's disease (PD) with mild cognitive impairment affecting around a quarter of patients in the early stages of their disease, and approximately half developing dementia by 10 years from diagnosis. H
Publikováno v:
Future Neurology. 8:605-607
Autor:
Alpar S. Lazar, Sarah L Mason, Travis Cruickshank, Roger A. Barker, Francesca Panin, Mel Ziman, Faye Begeti, Lucy M Collins
Publikováno v:
PLoS Currents
BACKGROUND: We investigated the use of a simple novel nut and bolt task in premanifest and manifest Huntington's disease (HD) patients to detect and quantify motor impairments at all stages of the disease.METHODS: Premanifest HD (n=24), manifest HD (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09fcf574fea95a5125382ad2a0a03c8c
https://ueaeprints.uea.ac.uk/id/eprint/61605/
https://ueaeprints.uea.ac.uk/id/eprint/61605/