Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Lucy Kirkham"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Dissemination of multiple myeloma into the bone marrow proceeds through sequential steps mediated by a variety of adhesion molecules and chemokines that eventually results in the extravasation of malignant plasma cells into this protective n
Externí odkaz:
https://doaj.org/article/0027f159d20e4443a71312c37e812095
Autor:
Mark Gurney, Arwen Stikvoort, Emma Nolan, Lucy Kirkham-McCarthy, Stanislav Khoruzhenko, Rama Shivakumar, Sonja Zweegman, Niels W.C.J. van de Donk, Tuna Mutis, Eva Szegezdi, Subhashis Sarkar, Michael O’Dwyer
Publikováno v:
Haematologica, Vol 107, Iss 2 (2020)
There is a strong biological rationale for the augmentation of allogeneic natural killer (NK) cell therapies with a chimeric antigen receptor (CAR) to enhance acute myeloid leukemia (AML) targeting. CD38 is an established immunotherapeutic target in
Externí odkaz:
https://doaj.org/article/b0166d6551d14cd29eee673fac8c0c91
Autor:
Alessandro Natoni, Mariah L. Farrell, Sophie Harris, Carolyne Falank, Lucy Kirkham-McCarthy, Matthew S. Macauley, Michaela R. Reagan, Michael O’Dwyer
Publikováno v:
Haematologica, Vol 105, Iss 2 (2020)
Aberrant glycosylation resulting from altered expression of sialyltransferases, such as ST3 β-galactoside α2-3-sialyltransferase 6, plays an important role in disease progression in multiple myeloma (MM). Hypersialylation can lead to increased immu
Externí odkaz:
https://doaj.org/article/0ad5f9da28a14ec79b3a3aae64f07875
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Huntington’s disease (HD) is a neurodegenerative disorder whose major symptoms include progressive motor and cognitive dysfunction. Cognitive decline is a critical quality of life concern for HD patients and families. The enzyme histone de
Externí odkaz:
https://doaj.org/article/83fb75d6d54c4e1bb96e9a37f243acff
Autor:
Kim Debacker, Aisling Frizzell, Olive Gleeson, Lucy Kirkham-McCarthy, Tony Mertz, Robert S Lahue
Publikováno v:
PLoS Biology, Vol 10, Iss 2, p e1001257 (2012)
Expansions of DNA trinucleotide repeats cause at least 17 inherited neurodegenerative diseases, such as Huntington's disease. Expansions can occur at frequencies approaching 100% in affected families and in transgenic mice, suggesting that specific c
Externí odkaz:
https://doaj.org/article/b927da874127465b9d9a9362fd86d0c4
Autor:
Alessandro Natoni, Marina Cerreto, Maria Stefania De Propris, Maria Teresa Petrucci, Francesca Fazio, Stefania Intoppa, Maria Laura Milani, Lucy Kirkham-McCarthy, Robert Henderson, Dawn Swan, Anna Guarini, Michael O’Dwyer, Robin Foà
Publikováno v:
Cancers; Volume 15; Issue 7; Pages: 2154
Multiple myeloma (MM) is a plasma cell disorder that develops in the bone marrow (BM) and is characterized by uncontrolled proliferation and the ability to disseminate to different sites of the skeleton. Sialofucosylated structures, particularly Sial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6174af36b573f5c3054f0b65e6b4724
Autor:
Sophie Harris, Alessandro Natoni, Matthew S. Macauley, Mariah Farrell, Michael O'Dwyer, Carolyne Falank, Michaela R. Reagan, Lucy Kirkham-McCarthy
Publikováno v:
Haematologica
Aberrant glycosylation resulting from altered expression of sialyltransferases, such as ST3 β-galactoside α2-3-sialyltransferase 6, plays an important role in disease progression in multiple myeloma (MM). Hypersialylation can lead to increased immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a613ef8c3f560563d44081f42cb4271
http://europepmc.org/articles/PMC7012485
http://europepmc.org/articles/PMC7012485
Autor:
Michael O’Dwyer, Enda Shevlin, Sarah Brophy, David Hermanson, Hallie Hintz, Neil Otto, Brianna Ettestad, Lucy Kirkham-McCarthy, Marjut Köylijärvi, David Hardwicke, Mary Reilly
Publikováno v:
Clinical Lymphoma Myeloma and Leukemia. 22:S45-S46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00b2c6cb0e4f5a3d180b98fc02544a5a
https://doi.org/10.1016/s2152-2650(22)00348-2
https://doi.org/10.1016/s2152-2650(22)00348-2
Autor:
Debbie Clark, Lucy Kirkham
Publikováno v:
International Journal of Healthcare Simulation.
In 2020 many healthcare students lost placement hours due to COVID-19. In response to this crisis, simulated placements were implemented to ensure students were able to achieve their practice hours. A pilot project was undertaken in November 2020. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adbe31dbb9e98289a3c6a5802db3363e
https://doi.org/10.54531/wgfr7996
https://doi.org/10.54531/wgfr7996
Autor:
Lucy Kirkham
During an episode of care, a patient may be attended by a variety of healthcare professionals. In\ud addition, healthcare service provision can be complex, and patients may feel that elements of their care\ud have been missed or delayed due to inadeq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::415856c82bf18ac68d598a9e91d2be48
https://shura.shu.ac.uk/28291/3/Kirkham_ProvidingInterprofessional(AM).pdf
https://shura.shu.ac.uk/28291/3/Kirkham_ProvidingInterprofessional(AM).pdf
