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Abstract 923: Ibrutinib inhibits malignant cell adhesion and migration and reduces tumor burden in lymph node and bone marrow in a murine model of mantle cell dissemination and progression

Autor: Padmaja Magadala, Joseph J. Buggy, Michelle Francesco, Lucy Jawed, Betty Chang, Stella Chang, Susanne M. Steggerda, Patricia Thiemann

Publikováno v: Cancer Research. 73:923-923

Introduction: Ibrutnib is a potent and selective Btk inhibitor that covalently modifies Cys481 in Btk and inhibits B cell antigen receptor (BCR) signaling. Ibrutinib is currently in a Phase II study in patients with relapsed or refractory mantle cell

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3c43a87969b4911609a1883c1fb90ae3
https://doi.org/10.1158/1538-7445.am2013-923

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