Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lucy J. Brooks"'
Autor:
Claudia Garcia-Diaz, Anni Pöysti, Elisabetta Mereu, Melanie P. Clements, Lucy J. Brooks, Felipe Galvez-Cancino, Simon P. Castillo, Wenhao Tang, Gordon Beattie, Lilas Courtot, Sara Ruiz, Federico Roncaroli, Yinyin Yuan, Samuel Marguerat, Sergio A. Quezada, Holger Heyn, Simona Parrinello
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112472- (2023)
Summary: Glioblastoma (GBM) recurrence originates from invasive margin cells that escape surgical debulking, but to what extent these cells resemble their bulk counterparts remains unclear. Here, we generated three immunocompetent somatic GBM mouse m
Externí odkaz:
https://doaj.org/article/2511e84f6c4a4bdfa932c7945c113d09
Autor:
Lucy J. Brooks, Melanie P. Clements, Jemima J. Burden, Daniela Kocher, Luca Richards, Sara Castro Devesa, Leila Zakka, Megan Woodberry, Michael Ellis, Zane Jaunmuktane, Sebastian Brandner, Gillian Morrison, Steven M. Pollard, Peter B. Dirks, Samuel Marguerat, Simona Parrinello
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glioma stem cells (GSCs) retain the ability to partially differentiate, but it is unclear how the brain microenvironment may influence this response. Here the authors show that glioblastoma cells infiltrating into the white matter acquire pre-oligode
Externí odkaz:
https://doaj.org/article/1dfd4c8671124520ac4d6ba779864aae
Autor:
Lucy J. Brooks, Melanie P. Clements, Jemima J. Burden, Daniela Kocher, Luca Richards, Sara Castro Devesa, Leila Zakka, Megan Woodberry, Michael Ellis, Zane Jaunmuktane, Sebastian Brandner, Gillian Morrison, Steven M. Pollard, Peter B. Dirks, Samuel Marguerat, Simona Parrinello
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/c6f6fdd59beb4ad2afd4c54046152174
Autor:
Lucy J. Brooks, Holly Simpson Ragdale, Ciaran Scott Hill, Melanie Clements, Simona Parrinello
Publikováno v:
Trends in neurosciences. 45(11)
Glioblastoma is the most common and aggressive primary brain cancer in adults and is almost universally fatal due to its stark therapeutic resistance. During the past decade, although survival has not substantially improved, major advances have been