Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

Autor: Julia R. Dorin, Heather MacPherson, Lucy J Mallin, Graeme R. Grimes, Glenn L. Millhauser, Sheila Webb, Matthew A. Nix, Sarah L. Cox, Fiona Semple, Christine Tyrrell, Colin A. Semple

Publikováno v: Semple, F, MacPherson, H, Webb, S, Cox, S L, Mallin, L J, Tyrrell, C, Grimes, G R, Semple, C A, Nix, M A, Millhauser, G L & Dorin, J R 2011, ' Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF ', European Journal of Immunology, vol. 41, no. 11, pp. 3291-300 . https://doi.org/10.1002/eji.201141648
European Journal of Immunology

β-Defensins are cationic host defense peptides that form an amphipathic structure stabilized by three intramolecular disulfide bonds. They are key players in innate and adaptive immunity and have recently been shown to limit the production of pro-in

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https://www.pure.ed.ac.uk/ws/files/8669556/Human_defensin_3_affects_the_activity_of_pro_inflammatory_pathways.pdf