Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lucy Horoszok"'
Autor:
Benjamin Santos, Savion Gropper, Thomas Roth, Thais Baleeiro, Lucy Horoszok, Fabiana D'Aniello, Guglietta Antonio
Publikováno v:
Human Psychopharmacology: Clinical and Experimental. 29:266-273
Objective A 5-h phase advance model of insomnia was used to evaluate the efficacy of lorediplon, a new non-benzodiazepine hypnotic. Methods Thirty-five male, healthy subjects were included in a five-way randomized cross-over study. During each of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a1ce3628fdeb3595f83cbfcaa4482a
https://doi.org/10.1002/hup.2395
https://doi.org/10.1002/hup.2395
Autor:
Mickaël Maudet, Jennifer M. A. Laird, Ronald Zemribo, Paul Jones, Michael Dabrowski, Andis Slaitas, Yevgeni Besidski, Gitte Terp, Karin Kolmodin, Andrea Penwell, Andrew Griffin, Didier Rotticci, Anna K. Sundgren-Andersson, Christopher Walpole, Dean Johnson, Alexander Munro, Yin Hu, Therese Lundström, Maryse Labarre, Inger Kers, Huascar Villanueva, Johan Bylund, Martin Nylöf, Mats Svensson, Denis Labrecque, Magali Harter, Sandrine Leclerc, William Brown, Sophie Dautrey, Shawn Johnstone, John Martino, Lucy Horoszok
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:6205-6211
Benzothiazole amides were identified as TRPV1 antagonists from high throughput screening using recombinant human TRPV1 receptor and structure-activity relationships were explored to pinpoint key pharmacophore interactions. By increasing aqueous solub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5999ae8c775dbcf4f87b0f920411e95
https://doi.org/10.1016/j.bmcl.2012.08.018
https://doi.org/10.1016/j.bmcl.2012.08.018
Publikováno v:
British Journal of Pharmacology. 132:1247-1254
1. We report the cloning and expression of a novel Caenorhabditis elegans polypeptide, GLC-3, with high sequence identity to previously cloned L-glutamate-gated chloride channel subunits from nematodes and insects. 2. Expression of glc-3 cRNA in XENO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30b72a2e22fc603edf9b79e2af343172
https://doi.org/10.1038/sj.bjp.0703937
https://doi.org/10.1038/sj.bjp.0703937
Autor:
Adrian J. Wolstenholme, Thomas M Skinner, Suchitra Jagannathan, Catherine L Critten, Lucy Horoszok, D L Laughton
Publikováno v:
Molecular and Biochemical Parasitology. 103:129-140
The alternatively-spliced Caenorhabditis elegans gbr-2/avr-14 gene encodes two subunits of the nematode ligand-gated chloride channel family which forms an important molecular target for the avermectin and related anthelminthics. We used reverse tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab9e79c46ae263db3c813aefeea7e26
https://doi.org/10.1016/s0166-6851(99)00120-6
https://doi.org/10.1016/s0166-6851(99)00120-6