Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lucy Hepburn"'
Autor:
Louise M C Webb, John C Pascall, Lucy Hepburn, Christine Carter, Martin Turner, Geoffrey W Butcher
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110294 (2014)
GTPases of the immunity-associated protein family (GIMAPs) are predominantly expressed in mature lymphocytes. Studies of rodents deficient in GIMAP1, GIMAP4, or GIMAP5 have demonstrated that these GTPases regulate lymphocyte survival. In contrast to
Externí odkaz:
https://doaj.org/article/b3ceed3a662b47bfa6c5bf76d9f4daf5
Publikováno v:
Anesthesia for Congenital Heart Disease. :710-740
Autor:
Chris Liyanage, Jethro Palmer, Nicole Withers, Tim Eglinton, Jamie Mosher, Fergus Evans, Juni Dasril, Magda M. Sakowska, Lucy Hepburn
Publikováno v:
ANZ Journal of Surgery. 91:2054-2059
BACKGROUND Globally, patients presenting with acute surgical disease in rural areas have poorer outcomes when compared to urban areas; little data are available regarding outcomes for New Zealand (NZ) rural patients. This study aimed to compare the s
Publikováno v:
Abstracts.
Over 18, 500 children and young people (CYP) come to Great Ormond Street for surgery each year, 50% of these will develop procedural anxiety prior to surgery, and this may be fleeting and transient or long lasting. ‘Deconstructing Fear’ is intend
Publikováno v:
Abstracts.
Background Brugada syndrome (BrS) is a cardiac ion channelopathy, typically affecting autosomal-dominantly inherited mutations in the SCN5A gene. BrS predisposes to potentially malignant arrhythmias and sudden cardiac death. Routinely administered an
Publikováno v:
Abstracts.
Approx 800,000 children in the UK present for have surgery every year This number is rising by approx. 11% per annum. Evidence suggests that up to 75% of these CYP’s will experience anxiety on hospitalisation. This procedural anxiety may be fleetin
Autor:
DirkJan Hijnen, Tomas Mustelin, Ian Strickland, Matthew A. Sleeman, Bret R. Sellman, Richard D. May, Lucy Hepburn
Publikováno v:
British Journal of Dermatology. 177:63-71
Atopic dermatitis (AD) is a complex, chronic inflammatory skin disorder affecting more than 10% of U.K. children and is a major cause of occupation-related disability. A subset of patients, particularly those with severe AD, are persistently colonize
Autor:
Suranjith L. Seneviratne, Nikolay V. Ogryzko, Katherine L. Hammond, Krisztina Hegyi, Bas G.J. Surewaard, M. Estée Török, Michael Otto, Tor Ny, Robin Antrobus, Pablo Moreno, Simon J. Foster, Petros Ligoxygakis, John E. Connolly, Lucy Hepburn, Karen Brown, Lihui Wang, Clare E. Bryant, Stephen A. Renshaw, Mark Schiebler, Arthur Kaser, Liliana Minichiello, Catherine Klapholz, Dorothy M Grogono, Sharon J. Peacock, C. Geoff Woods, Bernardo Montano Ochoa, Julien Cachat, Tomasz K. Prajsnar, Matthew T. G. Holden, Tom L. Blundell, Catherine A. Loynes, R. Andres Floto
Publikováno v:
Science. 346:641-646
Many key components of innate immunity to infection are shared between Drosophila and humans. However, the fly Toll ligand Spaetzle is not thought to have a vertebrate equivalent. We have found that the structurally related cystine-knot protein, nerv
Autor:
Andrea A. Kelleher, Lucy Hepburn
Publikováno v:
Anaesthesia & Intensive Care Medicine. 10:451-456
With advances in early treatment, babies with congenital heart disease are now usually surviving to adulthood. They are, therefore, increasingly presenting as adults to non-specialist units for medical care. A simple classification of grown-up congen
Autor:
Carine Dion, Geoffrey W. Butcher, Christine Carter, Margaret Graham, J. Ross Miller, Geoffrey Morgan, Silke Schnell, W. John Coadwell, Heinz Jacobs, John C. Pascall, Lucy Hepburn, Amanda Hutchings
Publikováno v:
Scopus-Elsevier
The Gimap/IAN family of GTPases has been implicated in the regulation of cell survival, particularly in lymphomyeloid cells. Prosurvival and prodeath properties have been described for different family members. We generated novel serological reagents