Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lucy H. Williams"'
Autor:
Martin T. Ferris, Sarah A. Schoenrock, Timothy R. Gershon, David B. Darr, Mark J. Zylka, J. Mauro Calabrese, James E. Faber, Laura G. Reinholdt, David W. Threadgill, John R. Shorter, Kathleen M. Caron, Lisa E. Gralinski, Robert S. Hagan, Glenn K. Matsushima, Yuyu Ren, Christopher M. Sassetti, Christiann H. Gaines, Bin Gu, Lori L. O'Brien, Sheryl S. Moy, Timothy A. Bell, Keegan Wardwell, Barbara J. Vilen, Terry Magnuson, Darla R. Miller, Clare M. Smith, Abraham A. Palmer, A. Wesley Burks, Fernando Pardo-Manuel de Villena, Celine L. St. Pierre, William Valdar, Rachel C. McMullan, Pablo Hock, Frank L. Conlon, Kevin C K Lloyd, Gudrun A. Brockmann, Anwica Kashfeen, Ginger D. Shaw, Steve Rockwood, Karen L. Mohlke, Matthew Blanchard, Alessandra Livraghi-Butrico, Benjamin D. Philpot, Rachel M Lynch, Scott H. Randell, J. Brennan, John Sebastian Sigmon, Vivek Kumar, Ralph S. Baric, Leonard McMillan, Mark T. Heise, Ernest G. Heimsath, Richard E. Cheney, Avani Saraswatula, Lucy H. Williams, Allison R. Rogala, Colton L. Linnertz, Caroline E. Y. Murphy, Dominic Ciavatta, Mike Kulis, Tal Kafri, Craig L. Franklin, Jason K. Whitmire, J. Charles Jennette, Maya L. Najarian, Cathleen M. Lutz, Jonathan C. Schisler, Lisa M. Tarantino, Folami Y. Ideraabdullah
Publikováno v:
Genetics: a periodical record of investigations bearing on heredity and variation, vol 216, iss 4
Genetics
Genetics
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well-annotated genome, wealth of genetic resources, and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f021d31a7f2e88239f86551bdc6e73b
https://escholarship.org/uc/item/7cq7g4tc
https://escholarship.org/uc/item/7cq7g4tc
Autor:
Christiann H. Gaines, Sheryl S. Moy, Mark T. Heise, Scott H. Randell, Matthew Blanchard, Vivek Kumar, Leonard McMillan, Darla R. Miller, Lucy H. Williams, Timothy A. Bell, Keegan Wardwell, Terry Magnuson, Mark J. Zylka, Christopher M. Sassetti, Craig L. Franklin, Ralph S. Baric, Sarah A. Schoenrock, Glenn K. Matsushima, Cathleen M. Lutz, James E. Faber, Maya L. Najarian, Yuyu Ren, Folami Y. Ideraabdullah, Jason K. Whitmire, Bin Gu, Jonathan C. Schisler, Pablo Hock, J. Charles Jennette, Celine L. St. Pierre, Lisa M. Tarantino, Samir N. P. Kelada, Karen L. Mohlke, Laura G. Reinholdt, Alessandra Livraghi-Butrico, Richard F. Loeser, Abraham A. Palmer, Robert S. Hagan, John R. Shorter, David W. Threadgill, Lori L. O'Brien, Kathleen M. Caron, Steve Rockwood, Kent Lloyd, Fernando Pardo-Manuel de Villena, Caroline E. Y. Murphy, A. Wesley Burks, Tal Kafri, Benjamin D. Philpot, David B. Darr, Avani Saraswatula, Ernest G. Heimsath, Richard E. Cheney, Allison R. Rogala, William Valdar, Dominic Ciavatta, Rachel C. McMullan, Ginger D. Shaw, Clare M. Smith, Frank L. Conlon, Barbara J. Vilen, John Sebastian Sigmon, Gudrun A. Brockmann, Anwica Kashfeen, Martin T. Ferris, Rachel M Lynch, Mauro Calabrese, Colton L. Linnertz, Timothy R. Gershon, J. Brennan, Lisa E. Gralinski, Mike Kulis
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well annotated genome, wealth of genetic resources and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d2895cb1fd85eea8a9b4a24d854cc2
https://doi.org/10.1101/2020.03.12.989400
https://doi.org/10.1101/2020.03.12.989400
Autor:
Yiyun Pan, Timothy A. Bell, Fernando Pardo-Manuel de Villena, Pablo Hock, Darla R. Miller, Katherine A Dalton, Lucy H. Williams, John R. Shorter, Benjamin D. Philpot, Bin Gu, Ginger D. Shaw
Publikováno v:
Epilepsia
OBJECTIVE: Animal studies remain essential for understanding mechanisms of epilepsy and identifying new therapeutic targets. However, existing animal models of epilepsy do not reflect the high level of genetic diversity found in the human population.
Autor:
Adam B. Burkholder, Karen Adelman, Christopher A. Lavender, Ginger W. Muse, David C. Fargo, Benjamin S. Scruggs, Telmo Henriques, Michiko O. Inouye, Lucy H. Williams
Publikováno v:
Genes & Development. 32:26-41
Regulation by gene-distal enhancers is critical for cell type-specific and condition-specific patterns of gene expression. Thus, to understand the basis of gene activity in a given cell type or tissue, we must identify the precise locations of enhanc
Autor:
Bin Gu, Shorter, Cooley Bc, Pablo Hock, Timothy A. Bell, Ginger D. Shaw, Pan Y, Katherine A Dalton, Benjamin D. Philpot, Darla R. Miller, Lucy H. Williams, de Villena Fp
Epilepsy is a neurological disorder with complex etiologies and genetic architecture. Animal models have a critical role in understanding the pathophysiology of epilepsy. Here we studied epilepsy utilizing a genetic reference population of Collaborat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c4f07a8db366c387d63de4e7172a95
Autor:
Darla R. Miller, Vishal Kumar Sarsani, Leonard McMillan, Paola Giusti-Rodríguez, John R. Shorter, Pablo Hock, Rachel C. McMullan, Anwica Kashfeen, Gary A. Churchill, Patrick F. Sullivan, Anuj Srivastava, Fernando Pardo-Manuel de Villena, Martin T. Ferris, Andrew P. Morgan, Maya L. Najarian, Lucy H. Williams, Timothy A. Bell, J. Sebastian Sigmon
Publikováno v:
Genetics
The Collaborative Cross (CC) is a multiparent panel of recombinant inbred (RI) mouse strains derived from eight founder laboratory strains. RI panels are popular because of their long-term genetic stability, which enhances reproducibility and integra
Autor:
Wei Sun, Lingyun Song, Gregory E. Crawford, Joshua Starmer, Piotr A. Mieczkowski, Della Yee, Terry Magnuson, Lucy H. Williams, J. Mauro Calabrese, Joshua W. Mugford
Publikováno v:
Cell. 151:951-963
Summary The inactive X chromosome's (Xi) physical territory is microscopically devoid of transcriptional hallmarks and enriched in silencing-associated modifications. How these microscopic signatures relate to specific Xi sequences is unknown. Theref
Autor:
Karen Adelman, Guang Hu, Lucy H. Williams, Ginger W. Muse, Adam B. Burkholder, George Fromm, Nolan G. Gokey, Telmo Henriques, David C. Fargo
Publikováno v:
Molecular cell. 58(2)
The remarkable capacity for pluripotency and self-renewal in embryonic stem cells (ESCs) requires a finely tuned transcriptional circuitry wherein the pathways and genes that initiate differentiation are suppressed, but poised to respond rapidly to d
Publikováno v:
Development (Cambridge, England). 138(10)
Repression of Xist RNA expression is considered a prerequisite to reversal of X-chromosome inactivation (XCI) in the mouse inner cell mass (ICM), and reactivation of X-linked genes is thought to follow loss of Xist RNA coating and heterochromatic mar
Autor:
Lucy H. Williams, Nicholas C. Kappas, M.E. Hartnett, Gefei Zeng, Sarah M. Taylor, Janet R. McColm, Victoria L. Bautch, Joseph B. Kearney
New blood vessel formation requires the coordination of endothelial cell division and the morphogenetic movements of vessel expansion, but it is not known how this integration occurs. Here, we show that endothelial cells regulate division orientation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874d23fdc52f89e4e617509694580182
https://europepmc.org/articles/PMC1794069/
https://europepmc.org/articles/PMC1794069/