Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lucy Freem"'
Autor:
Stephen J. Bush, Lucy Freem, Amanda J. MacCallum, Jenny O’Dell, Chunlei Wu, Cyrus Afrasiabi, Androniki Psifidi, Mark P. Stevens, Jacqueline Smith, Kim M. Summers, David A. Hume
Publikováno v:
BMC Genomics, Vol 19, Iss 1, Pp 1-19 (2018)
Abstract Background The domestic chicken (Gallus gallus) is widely used as a model in developmental biology and is also an important livestock species. We describe a novel approach to data integration to generate an mRNA expression atlas for the chic
Externí odkaz:
https://doaj.org/article/37c7943d6af743708adf60de70a96b41
Autor:
Lucy Freem, Kim M. Summers, Almas A. Gheyas, Androniki Psifidi, Kay Boulton, Amanda MacCallum, Rakhi Harne, Jenny O’Dell, Stephen J. Bush, David A. Hume
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
There is increasing recognition that the underlying genetic variation contributing to complex traits influences transcriptional regulation and can be detected at a population level as expression quantitative trait loci. At the level of an individual,
Externí odkaz:
https://doaj.org/article/461e7fcdfe1a4ffbbb1cc9261e7bcc17
Autor:
William K W Ho, Lucy Freem, Debiao Zhao, Kevin J Painter, Thomas E Woolley, Eamonn A Gaffney, Michael J McGrew, Athanasia Tzika, Michel C Milinkovitch, Pascal Schneider, Armin Drusko, Franziska Matthäus, James D Glover, Kirsty L Wells, Jeanette A Johansson, Megan G Davey, Helen M Sang, Michael Clinton, Denis J Headon
Publikováno v:
PLoS Biology, Vol 17, Iss 2, p e3000132 (2019)
Feathers are arranged in a precise pattern in avian skin. They first arise during development in a row along the dorsal midline, with rows of new feather buds added sequentially in a spreading wave. We show that the patterning of feathers relies on c
Externí odkaz:
https://doaj.org/article/eaeacd7112b1485b9555e43fb7a6f86d
Publikováno v:
PLoS Biology, Vol 16, Iss 4, p e2004162 (2018)
The vertebrate neuroepithelium is composed of elongated progenitors whose reciprocal attachments ensure the continuity of the ventricular wall. As progenitors commit to differentiation, they translocate their nucleus basally and eventually withdraw t
Externí odkaz:
https://doaj.org/article/ecf4f666cef94b3a8c2e85979e84e0ed
Autor:
Kim M. Summers, Lucy Freem, Lonneke Vervelde, Adam Balic, David A. Hume, Tuanjun Hu, Stephen J. Bush, Peter K. Kaiser, Zhiguang Wu
Publikováno v:
The Journal of Immunology. 202:1186-1199
The phosphatidylserine receptor TIM4, encoded by TIMD4, mediates the phagocytic uptake of apoptotic cells. We applied anti-chicken TIM4 mAbs in combination with CSF1R reporter transgenes to dissect the function of TIM4 in the chick (Gallus gallus). D
Autor:
Lucy Freem, Kay Boulton, Stephen J. Bush, Jenny O’Dell, Rakhi Harne, Androniki Psifidi, David A. Hume, Almas Gheyas, Kim M. Summers, Amanda MacCallum
Publikováno v:
Freem, L, Summers, K, Gheyas, A, Psifidi, A, Boulton, K, McCallum, A, O'Dell, J, Bush, S J & Hume, D 2019, ' Analysis of the progeny of sibling matings reveals regulatory variation impacting the transcriptome of immune cells in commercial chickens ', Frontiers in genetics . https://doi.org/10.3389/fgene.2019.01032
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)
Frontiers in Genetics
Frontiers in Genetics, Vol 10 (2019)
There is increasing recognition that the underlying genetic variation contributing to complex traits influences transcriptional regulation and can be detected at a population level as expression quantitative trait loci. At the level of an individual,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f80756afed5a4b3edf823b49bbe061ae
https://ora.ox.ac.uk/objects/uuid:ad260578-9304-4bbe-b419-a83189b9f9e7
https://ora.ox.ac.uk/objects/uuid:ad260578-9304-4bbe-b419-a83189b9f9e7
Autor:
David A. Hume, Stephen J. Bush, Jacqueline Smith, Lucy Freem, Jenny O’Dell, Chunlei Wu, Androniki Psifidi, Mark P. Stevens, Kim M. Summers, Cyrus Afrasiabi, Amanda MacCallum
Publikováno v:
Bush, S J, Freem, L, MacCallum, A J, O'Dell, J, Wu, C, Afrasiabi, C, Psifidi, A, Stevens, M P, Smith, J, Summers, K M & Hume, D A 2018, ' Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken ', BMC Genomics, vol. 19, no. 1, 594 (2018) . https://doi.org/10.1186/s12864-018-4972-7
BMC Genomics
BMC Genomics, Vol 19, Iss 1, Pp 1-19 (2018)
BMC Genomics
BMC Genomics, Vol 19, Iss 1, Pp 1-19 (2018)
BackgroundThe domestic chicken (Gallus gallus) is widely used as a model in developmental biology and is also an important livestock species. We describe a novel approach to data integration to generate an mRNA expression atlas for the chicken spanni
Publikováno v:
Journal of Anatomy. 217:651-664
Within the embryonic lung, intrinsic nerve ganglia, which innervate airway smooth muscle, are required for normal lung development and function. We studied the development of neural crest-derived intrinsic neurons within the embryonic mouse lung by c
Publikováno v:
Stem Cells in the Lung ISBN: 9783319210810
The respiratory system, comprising the lungs, trachea, vasculature, and associated neural tissues, carries out gas exchange essential for terrestrial life. During early embryonic development, the lung primordium, originating from the ventral foregut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e24fe7504f7a945fb246239d8e680d2
https://doi.org/10.1007/978-3-319-21082-7_4
https://doi.org/10.1007/978-3-319-21082-7_4
Publikováno v:
Organogenesis
Davey, M, McTeir, L, Barrie, A, Freem, L & Stephen, L 2014, ' Loss of cilia causes embryonic lung hypoplasia, liver fibrosis and cholestasis in the talpid3 ciliopathy mutant ', Organogenesis, vol. 10, no. 2, pp. 177-185 . https://doi.org/10.4161/org.28819
Davey, M, McTeir, L, Barrie, A, Freem, L & Stephen, L 2014, ' Loss of cilia causes embryonic lung hypoplasia, liver fibrosis and cholestasis in the talpid3 ciliopathy mutant ', Organogenesis, vol. 10, no. 2, pp. 177-185 . https://doi.org/10.4161/org.28819
Sonic hedgehog plays an essential role in maintaining hepatoblasts in a proliferative non-differentiating state during embryogenesis. Transduction of the Hedgehog signaling pathway is dependent on the presence of functional primary cilia and hepatobl