Výsledky vyhledávání

Supplementary Tables S1-S8 from Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors

Autor: Ignacio I. Wistuba, Hilary McElwaine-Johnn, David Vining, Graciela M. Nogueras-Gonzalez, Elisabeth A. Bone, Helen Berryman, Lucy Coe, Franck A. Silva, Kemal Haque, James Dow, Alexander R.L. Cecil, Simin Kiany, Henry H. Vo, Cara Haymaker, Carrie A. Cartwright, Philip A. Beer, Apostolia M. Tsimberidou

Supplementary Tables

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317fa511ab6534bc011525e90147418f
https://doi.org/10.1158/1078-0432.22480343.v1

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Figures S1 - S6 from Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors

Supplementary Figures

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d26f8db429394eb60f6de8e2974307d
https://doi.org/10.1158/1078-0432.22480346

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Data from Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors

Purpose:Inhibition of histone deacetylase 6 (HDAC6) is predicted to deliver both direct antitumor activity and modulation of the antitumor immune response. This study describes the development of a novel HDAC6 inhibitor.Patients and Methods:KA2507 wa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19858b5e25a20b1e682ee91ab8838811
https://doi.org/10.1158/1078-0432.c.6530423

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Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors

Autor: Apostolia Maria Tsimberidou, Cara Haymaker, Franck Alexandre Silva, Simin Kiany, Kemal Haque, Lucy Coe, Carrie Cartwright, Helen Berryman, Graciela M. Nogueras-Gonzalez, James Dow, David Vining, Alexander Richard Liam Cecil, Henry H. Vo, Elisabeth A. Bone, Ignacio I. Wistuba, Philip A. Beer, Hilary McElwaine-Johnn

Publikováno v: Clinical Cancer Research. 27:3584-3594

Purpose: Inhibition of histone deacetylase 6 (HDAC6) is predicted to deliver both direct antitumor activity and modulation of the antitumor immune response. This study describes the development of a novel HDAC6 inhibitor. Patients and Methods: KA2507

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa6f156927db60cbf7c47ada3193d33
https://doi.org/10.1158/1078-0432.ccr-21-0238

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Dissertation/ Thesis

Redefining the role of 'non-professionally affiliated' workers in community mental health care : a qualitative exploration of co-worker and client relationships

Autor: Harrison, Deborah Lucy Coe

Recent changes to UK health care policy have led to a dramatic increase in the non-professionally affiliated (NPA) workforce. Despite the growing presence and importance of NPA roles as part of the ‘drive for better value’, until recently they ex

Externí odkaz: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.567060

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Akademický článek

Leguminosas e seus efeitos sobre propriedades físicas do solo e produtividade do mamoeiro 'Tainung 1' Leguminous plants and their effects on soil physical properties and productivity of papaya 'Tainung 1'

Autor: José Eduardo Borges de Carvalho, Lucy Coelho Lopes, Ana Maria de Amorim Araújo, Luciano da Silva Souza, Ranulfo Corrêa Caldas, Carlos Alberto Daltro Junior, Lícia Lemos de Carvalho, Antonio Alberto Rocha Oliveira, Rosane Cardoso dos Santos

Publikováno v: Revista Brasileira de Fruticultura, Vol 26, Iss 2, Pp 335-338 (2004)

Conduziu-se um experimento no período de junho 1998 a dezembro de 2000 na Escola de Agronomia da Universidade Federal da Bahia, em Cruz das Almas, em um Latossolo Amarelo álico coeso para avaliar o impacto do manejo de práticas melhoradoras sobre

Externí odkaz: https://doaj.org/article/579e1d73263d41fe9f4fa9301280b20c

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