Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lucy Cassar"'
Publikováno v:
Protein & Cell, Vol 8, Iss 1, Pp 39-54 (2016)
ABSTRACT Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell proliferation, but it remains unclear how extracellular cues regulate telomerase lengthening of telomeres. Here we report that th
Externí odkaz:
https://doaj.org/article/ec2417c9aa2e4be2bbbeb97463a55165
Autor:
He Li, Alexander R. Pinto, Lucy Cassar, Craig Nicholls, Jun-Ping Liu, Lihui Wang, Ruping Chen
Publikováno v:
Protein & Cell, Vol 8, Iss 1, Pp 39-54 (2016)
Protein & Cell
Protein & Cell
Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell proliferation, but it remains unclear how extracellular cues regulate telomerase lengthening of telomeres. Here we report that the cytokin
Publikováno v:
Molecular and Cellular Endocrinology. 320:97-105
Recent studies suggest that transforming growth factor beta (TGF-beta) inhibits telomerase activity by repression of the telomerase reverse transcriptase (TERT) gene. In this report, we show that TGF-beta induces TERT repression-dependent apoptosis i
Publikováno v:
The FASEB Journal. 23
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(6)
Human telomerase reverse transcriptase (hTERT) is central to maintain telomeres for continuous cell proliferation, but it remains unknown how extracellular cues regulate telomerase maintenance of telomeres. Here we report that the cytokine bone morph
Publikováno v:
Cancer research. 68(22)
Telomere maintenance is critical in tumor cell immortalization. Here, we report that the cytokine bone morphogenetic protein-7 (BMP7) inhibits telomerase activity that is required for telomere maintenance in cervical cancer cells. Application of huma
Publikováno v:
Cell research. 16(10)
Nasopharyngeal carcinoma (NPC) is a common cancer in Southern China and Southeast Asia. The disease is a poorly differentiated carcinoma without effective cure, and the mechanism underlying its development remains largely unknown. Of several factors
Publikováno v:
The FASEB Journal. 23:1880-1880
Human telomerase reverse transcriptase (hTERT) is central to maintain telomeres for continuous cell proliferation, but it remains unknown how extracellular cues regulate telomerase maintenance of telomeres. Here we report that the cytokine bone morph